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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 17, 2014 - Issue 5
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Original Research Papers

Modulation of oxidative stress, apoptosis, and calcium entry in leukocytes of patients with multiple sclerosis by Hypericum perforatum

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References

  • Naegele M, Tillack K, Reinhardt S, Schippling S, Martin R, Sospedra M. Neutrophils in multiple sclerosis are characterized by a primed phenotype. J Neuroimmunol 2012;18:242:60–71
  • Amor S, Puentes F, Baker D, van der Valk P. Inflammation in neurodegenerative diseases. Immunology 2010;129:154–69.
  • Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH. Mechanisms underlying inflammation in neurodegeneration. Cell 2010;140:918–34.
  • Feisst C, Werz O. Suppression of receptor-mediated Ca2+ mobilization and functional leukocyte responses by hyperforin. Biochem Pharmacol 2004;67(8):1531–9.
  • Nazıroğlu M. New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose. Neurochem Res 2007;32:1990–2001.
  • Puertollano MA, Puertollano E, de Cienfuegos GÁ, de Pablo MA. Dietary antioxidants: immunity and host defense. Curr Top Med Chem 2011;11:1752–66.
  • Kayan M, Nazıroğlu M, Ovey IS, Aykur M, Uğuz AC, Yürekli VA. Non-ionic contrast media induces oxidative stress and apoptosis through Ca(2+) influx in human neutrophils. J Membr Biol 2012;245(12):833–40.
  • Koch M, Mostert J, Arutjunyan AV, Stepanov M, Teelken A, Heersema D, et al. Plasma lipid peroxidation and progression of disability in multiple sclerosis. Eur J Neurol 2007;14(5):529–33.
  • Lutskii MA, Esaulenko IE. Oxidant stress in the pathogenesis of multiple sclerosis. Neurosci Behav Physiol 2007;37:209–13.
  • Gonsette RE. Neurodegeneration in multiple sclerosis: the role of oxidative stress and excitotoxicity. J Neurol Sci 2008;274(1–2):48–53.
  • Ghabaee M, Jabedari B, Al-E-Eshagh N, Ghaffarpour M, Asadi F. Serum and cerebrospinal fluid antioxidant activity and lipid peroxidation in Guillain-Barre syndrome and multiple sclerosis patients. Int J Neurosci 2010;120(4):301–4.
  • Sahin M, Uğuz AC, Demirkan H, Nazıroğlu M. Colchicine modulates oxidative stress in serum and leucocytes from remission patients with Family Mediterranean Fever through regulation of Ca2+ release and the antioxidant system. J Membr Biol 2011;240:55–62.
  • Ruiz A, Matute C, Alberdi E. Intracellular Ca2+ release through ryanodine receptors contributes to AMPA receptor-mediated mitochondrial dysfunction and ER stress in oligodendrocytes. Cell Death Dis 2010;15;1:e54.
  • Espino J, Mediero M, Bejarano I, Lozano GM, Ortiz A, García JF, et al. Reduced levels of intracellular calcium releasing in spermatozoa from asthenozoospermic patients. Rep Biol Endocrinol 2009;7:11.
  • Espino J, Bejarano I, Redondo PC, Rosado JA, Barriga C, Reiter RJ, et al. Melatonin reduces apoptosis induced by calcium signaling in human leukocytes: Evidence for the involvement of mitochondria and Bax activation. J Membr Biol 2010;233:105–118.
  • Espino J, Bejarano I, Paredes SD, Barriga C, Reiter RJ, Pariente JA, et al. Melatonin is able to delay endoplasmic reticulum stress-induced apoptosis in leukocytes from elderly humans. Age (Dordr) 2011;33(4):497–507.
  • Zou YP, Lu YH, Wei DZ. Protective effects of a flavonoid-rich extract of Hypericum perforatum L. against hydrogen peroxide-induced apoptosis in PC12 cells. Phytother Res. 2010;24( Suppl 1):S6–10.
  • Liu JY, Liu Z, Wang DM, Li MM, Wang SX, Wang R, et al. Induction of apoptosis in K562 cells by dicyclohexylammonium salt of hyperforin through a mitochondrial-related pathway. Chem Biol Interact 2011;190(2–3):91–101.
  • Albert D, Zündorf I, Dingermann T, Müller WE, Steinhilber D, Werz O. Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase. Biochem Pharmacol 2002;64:1767–75.
  • Leuner K, Li W, Amaral MD, Rudolph S, Calfa G, Schuwald AM, et al. Hyperforin modulates dendritic spine morphology in hippocampal pyramidal neurons by activating Ca(2+)-permeable TRPC6 channels. Hippocampus 2013;23:40–52.
  • Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227–31.
  • Uğuz AC, Cig B, Espino J, Bejarano I, Nazıroğlu M, Rodríguez AB, et al. Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells. J Pineal Res 2012;53:91–8.
  • Uğuz AC, Naziroğlu M, Espino J, Bejarano I, González D, Rodríguez AB, et al. Selenium modulates oxidative stress-induced cell apoptosis in human myeloid HL-60 cells through regulation of calcium release and caspase-3 and -9 activities. J Membr Biol 2009;232(1–3):15–23.
  • Grynkiewicz C, Poenie M, Tsien RY. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985;260:3440–50.
  • Heemskerk JW, Feijge MA, Henneman L, Rosing J, Hemker HC. The Ca2+-mobilizing potency of alpha-thrombin and thrombin receptor-activating peptide on human platelets concentration and time effects of thrombin-induced Ca2+ signalling. Eur J Biochem 1997;249:547–55.
  • Placer ZA, Cushman L, Johnson BC. Estimation of products of lipid peroxidation (malonyldialdehyde) in biological fluids. Anal Biochem 1966;16:359–64.
  • Sedlak J, Lindsay RHC. Estimation of total, protein bound and non-protein sulfhydryl groups in tissue with Ellmann's reagent. Anal Biochem 1968;25:192–205.
  • Lawrence RA, Burk RF. Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun 1976;71:952–8.
  • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin- Phenol reagent. J Biol Chem 1951;193:265–75.
  • Desai ID. Vitamin E analysis methods for animal tissues. Methods Enzymol 1984;105:138–47.
  • Suzuki J, Katoh N. A simple and cheap method for measuring vitamin A in cattle using only a spectrophotometer. Jpn J Vet Sci 1990;52:1282–4.
  • Nazıroğlu M, Karaoğlu A, Aksoy AO. Selenium and high dose vitamin E administration protects cisplatin-induced oxidative damage to renal, liver and lens tissues in rats. Toxicology 2004;195(2–3):221–30.
  • Jagota SK, Dani HM. A new colorimetric technique for the estimation of vitamin C using Folin phenol reagent. Anal Biochem 1982;127:178–82.
  • Uğuz AC, Nazıroğlu M. Effects of selenium on calcium signaling and apoptosis in rat dorsal root ganglion neurons induced by oxidative stress. Neurochem Res 2012;37:1631–8.
  • Nazıroğlu M, Dikici DM, Dursun S. Role of oxidative stress and Ca2+ signaling on molecular pathways of neuropathic pain in diabetes: focus on TRP channels. Neurochem Res 2012;37:2065–75.
  • Nazıroğlu M. Molecular role of catalase on oxidative stress-induced Ca(2+) signaling and TRP cation channel activation in nervous system. J Recept Signal Transduct Res 2012;32:134–41.
  • Heilmann J, Winkelmann K, Sticher O. Studies on the antioxidative activity of phloroglucinol derivatives isolated from hypericum species. Planta Med 2003;69:202–6.
  • Meinke MC, Schanzer S, Haag SF, Casetti F, Müller ML, Wölfle U, et al. In vivo photoprotective and anti-inflammatory effect of hyperforin is associated with high antioxidant activity in vitro and ex vivo. Eur J Pharm Biopharm 2012;81(2):346–50.
  • Jang MH, Lee TH, Shin MC, Bahn GH, Kim JW, Shin DH, et al. Protective effect of Hypericum perforatum Linn (St. John's wort) against hydrogen peroxide-induced apoptosis on human neuroblastoma cells. Neurosci Lett 2002;329:177–80.
  • Karg E, Klivenyi P, Bencsik K, Turi S, Vecsei L. Alpha-tocopherol and NADPH in the erythrocytes and plasma of multiple sclerosis patients. Effect of interferon-beta-1b treatment. Eur Neurol 2003;50:215–19.
  • Salemi G, Gueli MC, Vitale F, Battaglieri F, Guglielmini E, Ragonese P, et al. Blood lipids, homocysteine, stress factors, and vitamins in clinically stable multiple sclerosis patients. Lipids Health Dis 2010;9:19.
  • Jiménez-Jiménez FJ, de Bustos F, Molina JA, de Andrés C, Gasalla T, Ortí-Pareja M, et al. Cerebrospinal fluid levels of alpha-tocopherol in patients with multiple sclerosis. Neurosci Lett 1998;249:65–7.
  • Tasset I, Agüera E, Sánchez-López F, Feijóo M, Giraldo AI, Cruz AH, et al. Peripheral oxidative stress in relapsing-remitting multiple sclerosis. Clin Biochem 2012;45:440–4.
  • Korkmaz S, Erturan I, Nazıroğlu M, Uğuz AC, Ciğ B, Övey IS. Colchicine modulates oxidative stress in serum and neutrophil of patients with Behçet disease through regulation of Ca2+ release and antioxidant system. J Membr Biol 2011;244:113–20.
  • Di Ilio C, Arduini A, Del Boccio G, La Rovere G, Federici G. Glutathione redox cycle enzyme activities in erythrocytes of multiple sclerosis patients. Clin Physiol Biochem 1986;4:120–4.
  • Heiner I, Eisfeld J, Luckhoff A. Role and regulation of TRP channels in neutrophil granulocytes. Cell Calcium 2003;33:533–40.
  • Krishtal O, Lozovaya N, Fisunov A, Tsintsadze T, Pankratov Y, Kopanitsa M, et al. Modulation of ion channels in rat neurons by the constituents of Hypericum perforatum. Pharmacopsychiatry 2001;34( Suppl 1):S74–82.
  • Chatterjee S, Filippov V, Lishko P, Maximyuk O, Nöldner M, Krishtal O. Hyperforin attenuates various ionic conductance mechanisms in the isolated hippocampal neurons of rat. Life Sci 1999;65:2395–405.
  • Lin Y, Zhang JC, Fu J, Chen F, Wang J, Wu ZL, et al. Hyperforin attenuates brain damage induced by transient middle cerebral artery occlusion (MCAO) in rats via inhibition of TRPC6 channels degradation. J Cereb Blood Flow Metab 2013;33(2):253–62.

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