The Evaluation of iron overload through hepcidin level and its related factors in myelodysplastic syndromes

References

• Tefferi A, Vardiman JV. Myelodysplastic syndromes. N Engl J Med. 2009;361(19):1872–85.
   PubMed Web of Science ®Google Scholar
• Mahesh S, Ginzburg Y, Verma A. Iron overload in myelodysplastic syndromes. Leuk Lymphoma 2008;49(3):427–38.
   PubMed Web of Science ®Google Scholar
• Tanno T, Miller JL. Iron loading and overloading due to ineffective erythropoiesis. Adv Hematol. 2010;2010:358283.
   PubMedGoogle Scholar
• Gattermann N, Rachmilewitz EA. Iron overload in MDS-pathophysiology, diagnosis, and complications. Ann Hematol. 2011;90(1):1–10.
   PubMed Web of Science ®Google Scholar
• Ganz T, Nemeth E. Hepcidin and disorders of iron metabolism. Annu Rev Med. 2011;62:347–60.
   PubMed Web of Science ®Google Scholar
• Nemeth E. Iron regulation and erythropoiesis. Curr Opin Hematol. 2008;15(3):169–75.
   PubMed Web of Science ®Google Scholar
• Tanno T, Noel P, Miller JL. Growth differentiation factor 15 in erythroid health and disease. Curr Opin Hematol. 2010;17(3):184–90.
   PubMed Web of Science ®Google Scholar
• Tanno T, Bhanu NV, Oneal PA, Goh SH, Staker P, Lee YT. High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nat Med. 2007;13(9):1096–101
   PubMed Web of Science ®Google Scholar
• Tanno T, Porayette P, Sripichai O, Noh SJ, Byrnes C, Bhupatiraju A. Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells. Blood. 2009;114(1):181–6.
   PubMed Web of Science ®Google Scholar
• Pinto JP, Dias V, Zoller H, Porto G, Carmo H, Carvalho F. Hepcidin messenger RNA expression in human lymphocytes. Immunology. 2009;130(2):217–30.
   Web of Science ®Google Scholar
• Fragasso A, Ciancio A, Mannarella C. Myocardial iron overload assessed by magnetic resonance imaging (MRI)T2* in multi-transfused patients with thalassemia and acquired anemias. Eur J Intern Med. 2011;22(1):62–5.
   PubMed Web of Science ®Google Scholar
• Cheng HL, Holowka S, Moineddin R, Odame I. Liver iron overload assessment by T2* magnetic resonance imaging in pediatric patients: an accuracy and reproducibility study. Am J Hematol. 2012;87(4):435–7.
   PubMed Web of Science ®Google Scholar
• Brunning R, Orazi A, Germing U, Porwit A, Baumann I. Myelodysplastic syndromes. In: , Swerdlow S, Campo E, Harris NL, et al.(eds.) World Health Organization classification of tumours of haematopoietic and lymphoid tissue, 4th ed. Lyon, France: IARC Press; 2008. p. 88–103.
   Google Scholar
• Greenberg P, Cox C, LeBeau MM, Fenaux P, Morel P, Sanz G, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood. 1997;89(6):2079–88.
   PubMed Web of Science ®Google Scholar
• Malcovati L, Germing U, Kuendgen A, Della Porta MG, Pascutto C, Invernizzi R. Time-dependent prognostic scoring system for predicting survival and leukemic evolution in myelodysplastic syndromes. J Clin Oncol. 2007;25(23):3503–10.
   PubMed Web of Science ®Google Scholar
• Greenberg PL, Attar E, Bennett JM, Bloomfield CD, De Castro CM, Deeg HJ. NCCN clinical practice guidelines in oncology: myelodysplastic syndromes. J Natl Compr Cancer Netw. 2011;9(1):30–56.
   PubMed Web of Science ®Google Scholar
• Li X, Xu F, He Q, Wu L, Zhang Z, Chang C. Comparison of immunological abnormalities of lymphocytes in bone marrow in myelodysplastic syndrome (MDS) and aplastic anemia (AA). Intern Med. 2010;49(14):1349–55.
   PubMed Web of Science ®Google Scholar
• Ghoti H, Rachmilewitz EA, Simon-Lopez R, Gaber R, Katzir Z, Konen E. Evidence for tissue iron overload in long-term hemodialysis patients and the impact of withdrawing parenteral iron. Eur J Haematol. 2012;89(1):87–93.
   PubMed Web of Science ®Google Scholar
• Malcovati L, Della Porta MG, Pascutto C, Invernizzi R, Boni M, Travaglino E. Prognostic factors and life expectancy in myelodysplastic syndromes classified according to WHO criteria: a basis for clinical decision making. J Clin Oncol. 2005;23(30):7594–603.
   PubMed Web of Science ®Google Scholar
• Malcovati L, Della Porta MG, Cazzola M. Predicting survival and leukemic evolution in patients with myelodysplastic syndrome. Haematologica. 2006;91(12):1588–90.
   PubMed Web of Science ®Google Scholar
• Platzbecker U, Hofbauer LC, Ehninger G, Hölig K. The clinical, quality of life, and economic consequences of chronic anemia and transfusion support in patients with myelodysplastic syndromes. Leuk Res. 2012;36(5):525–36.
   PubMed Web of Science ®Google Scholar
• Park CH, Valore EV, Waring AJ, Ganz T. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem. 2001;276(11):7806–10.
   PubMed Web of Science ®Google Scholar
• Santini V, Girelli D, Sanna A, Martinelli N, Duca L, Campostrini N. Hepcidin levels and their determinants in different types of myelodysplastic syndromes. PLoS One. 2011;6(8):e23109.
   PubMed Web of Science ®Google Scholar
• Ramirez JM, Schaad O, Durual S, Cossali D, Docquier M, Beris P. Growth differentiation factor 15 production is necessary for normal erythroid differentiation and is increased in refractory anaemia with ring-sideroblasts. Br J Haematol. 2009;144(2):251–62.
   PubMed Web of Science ®Google Scholar
• Finkenstedt A, Bianchi P, Theurl I, Vogel W, Witcher DR, Wroblewski VJ. Regulation of iron metabolism through GDF15 and hepcidin in pyruvate kinase deficiency. Br J Haematol. 2008;144(5):789–93.
   PubMed Web of Science ®Google Scholar
• Tamary H, Shalev H, Perez-Avraham G, Zoldan M, Levi I, Swinkels DW. Elevated growth differentiation factor 15 expression in patients with congenital dyserythropoietic anemia type I. Blood. 2008;112(13):5241–4.
   PubMed Web of Science ®Google Scholar
• van Deuren M, Kroot JJ, Swinkels DW. Time-course analysis of serum hepcidin, iron and cytokines in a C282Y homozygous patient with Schnitzler's syndrome treated with IL-1 receptor antagonist. Hematologica. 2009;94(9):1297–300.
   PubMed Web of Science ®Google Scholar
• Gorak-Stolinska P, Truman JP, Kemeny DM, Noble A. Activation-induced cell death of human T-cell subsets is mediated by Fas and granzyme B but is independent of TNF-alpha. J Leukoc Biol. 2001;70(5):756–66.
   PubMed Web of Science ®Google Scholar
• Tsuda H, Yamasaki H. Type I and type II T-cell profiles in aplastic anemia and refractory anemia. Am J Hematol. 2000;64(4):271–4.
   PubMed Web of Science ®Google Scholar
• Agius E, Lacy KE, Vukmanovic-Stejic M, Jagger AL, Papageorgiou AP, Hall S. Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging. J Exp Med. 2009;206(9):1929–40.
   PubMed Web of Science ®Google Scholar