REFERENCES
- Salcman M. Glioblastoma and malignant astrocytoma. In: Kaye AH and Laws ER, eds. Brain Tumors, Edinburgh: Churchill Livingstone, 1995: pp. 449-479
- Bello L, Carrabba G, Giussani C, et al. Low-dose chemotherapy combined with an antiangiogenic drug reduces human glioma growth in vivo. Cancer Res 2001; 61: 7501–7506
- Ito N, Sawa H, Nagane M, et al. Inhibitory effects of sodium butyrate on proliferation and invasiveness of human glioma cells. Neurosurgery 2001; 49: 430–437
- Nagane M, Huang HJS, Cavenee WK. Causes of drug resistance and novel therapeutic opportunities for the treatment of gl ioblas-toma. Drug Resist Updat 1999; 2: 30–37
- Linskey ME, Gilbert MR. A review with implications for new directions in neuro-oncology. Neurosurgery 1995; 36: 1–22
- Engelhard HH, Duncan HA, Kim S, et al. Therapeutic effects of sodium butyrate on gliomas cells in vitro and in the rat C6 glioma model. Neurosurgery 2001; 48: 616–625
- Li XN, Du ZW, Huang Q. Modulation effects of hexamethylene bisacetamide on growth and differentiation of cultured human malignant gliomas cells. ] Neurosurg 1996; 84: 831–838
- Li XN, Du ZW, Huang Q, et al. Growth-inhibitory and differentiation-inducing activity of dimethyformamide in cultured human malignant gliomas cells. Neurosurgery 1997; 40: 1250–1259
- Li XN, Parikh S, Shu Q, et al. Phenybutyrate and phenylacetate induce differentiation and inhibit proliferation of human medullo-blastoma cells. Clin Cancer Res 2004; 10: 1150–1159
- Stockhammer G, Manley GT, Johnson R, et al. Inhibition of proliferation and induction of differentiation in medulloblastoma-and astrocytoma-derived cell lines with phenylacetate. I Neurosurg 1995; 83: 672–681
- Parker KK, Norenberg MD, Vernadakis A. Transdifferentiation of C6 glial cells in culture. Science 1980; 208: 179–181
- Segovia J, Lawless GM, Tillakaratne NJK, et al. Cyclic AMP decreases the expression of a neuronal marker (GAD67) and increases the expression of an astroglial marker (GFAP) in C6 cells. I Neurochem 1994; 63: 1218–1225
- Hai J, Lin Q, Lu Y, et al. Growth inhibition and induction of differentiation by panaxydol in rat C6 glioma cells. Neurol Res 2008; 30: 99–105
- Anciaux K, Dommelen KV, Nicolg S, et al. Cyclic AMP-mediated induction of the glial fibrillary acidic protein is independent of protein kinase A activation in rat C6 glioma. I Neurosci Res 1997; 48: 324–333
- Chen TC, Hinton DR, Zidovetzki R, et al. Up-regulation of the cAMP/PKA pathway inhibits proliferation, induces differentiation and leads to apoptosis in malignant gliomas. Lab Invest 1998; 78: 165–174
- Claes P, Kolen KV, Roymans D, et al. Reactive blue 2 inhibition of cyclic AMP-dependent differentiation of rat C6 glioma cells by purinergic receptor-independent inactivation of phosphatidylino-sitol 3-kinase. Biochem Pharmacol 2004; 67: 1489–1498
- Nakagawa M, Nakashima S, Banno Y, et al. Increased expression and secretion of r-Gsp protein, rat counterpart of complement C1s precursor, during cyclic AMP-induced differentiation in rat C6 glioma cells. Mol Brain Res 2002; 106: 12–21
- Roymans D, Grobben B, Class P, et al. Protein tyrosine kinase-dependent regulation of adenylate cyclase and phosphatidylino-sitol 3-kinase activates the expression of glial fibrillary acidic protein upon induction of differentiation in rat C6 glioma. Cell Biol Int 2001; 25: 467–474
- Hai J, Lin Q, Lu Y, et al. Induction of apoptosis in rat C6 glioma cells by panaxydol. Cell Biol Int 2007; 31: 711–715
- Lin Q, Zhao X, Lu Y, et al. Study on the lipophilic components of Panax notoginseng. Chin Tradit Herbal Drugs 2002; 33: 490–492
- Mosman T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol 1983; 65: 55–63
- Takanaga H, Yoshitake T, Hara S, et al. cAMP-induced astrocytic differentiation of C6 glioma cells is mediated by autocrine interleukin-6. J Biol Chem 2004; 279: 15441–15447
- Eng LF, Ghirnikar RS, Lee YL. GI ial fibrillary acidic protein: GFAP-thirty-one years (1969-2000). Neurochem Res 2000; 25: 1439–1451
- Engelhard HH, Duncan HA, Canto MD. Molecular characteriza-tion of glioblastoma cell differentiation. Neurosurgery 1997; 41: 886–897
- Rutka JT, Hubbard SL, Fukuyama K, et al. Effects of antisense glial fibrillary acidic protein complementary DNA on the growth, invasion, and adhesion of human astrocytoma cells. Cancer Res 1994; 54: 3267–3272
- Shirsat NV, Kayal JJ, Shaikh S, et al. Growth inhibition and differentiation of C6 glioma cells on treatment with HMBA. Cell Biol Int 2001; 25: 621–627
- Kajiwara K, Orita T, Nishizaki T, et al. Glial fibrillary acidic protein (GFAP) expression and nucleolar organizer regions (NORs) in human gliomas. Brain Res 1992; 572: 314–318
- Roger PP, Reuse S, Maehaut C, et al. Multiple facets of the modulation of growth by cAMP. Vitam Horm 1995; 51: 59–191
- Brenner M. Structure and transcriptional regulation of the GFAP gene. Brain Pathol 1994; 4: 245–257