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Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 34, 2012 - Issue 3
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Original Article

Vascular, electrophysiological, and metabolic consequences of cortical spreading depression in a mouse model of simulated neurosurgical conditions

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Pages 223-231 | Published online: 12 Nov 2013

References

  • Lauritzen M, Dreier JP, Fabricius M, Hartings JA, Graf R, Strong AJ. Clinical relevance of cortical spreading depression in neurological disorders: migraine, malignant stroke, subarachnoid and intracranial hemorrhage, and traumatic brain injury. J Cereb Blood Flow Metab. 2011;31(1):17–35.
  • Leao AA. Further observations on the spreading depression of activity in the cerebral cortex. J Neurophysiol. 1947;10(6):409–14.
  • Leao AA. The slow voltage variation of cortical spreading depression of activity. Electroencephalogr Clin Neurophysiol. 1951;3(3):315–21.
  • Dreier JP, Major S, Manning A, Woitzik J, Drenckhahn C, Steinbrink J, et al.. Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage. Brain. 2009;132(Pt 7):1866–81.
  • Bosche B, Graf R, Ernestus RI, Dohmen C, Reithmeier T, Brinker G, et al.. Recurrent spreading depolarizations after subarachnoid hemorrhage decreases oxygen availability in human cerebral cortex. Ann Neurol. 2010;67(5):607–17.
  • Hartings J, Strong AJ, Fabricius M, Manning A, Bhatia R, Dreier JP, et al.. Spreading depolarizations and late secondary insults after traumatic brain injury. J Neurotrauma. 2009;26(11):1857–66.
  • Dohmen C, Sakowitz OW, Fabricius M, Bosche B, Reithmeier T, Ernestus RI, et al.. Spreading depolarizations occur in human ischemic stroke with high incidence. Ann Neurol. 2008;63(6):720–8.
  • Dreier JP, Woitzik J, Fabricius M, Bhatia R, Major S, Drenckhahn C, et al.. Delayed ischaemic neurological deficits after subarachnoid haemorrhage are associated with clusters of spreading depolarizations. Brain. 2006;129(Pt 12):3224–37.
  • Fabricius M, Fuhr S, Willumsen L, Dreier JP, Bhatia R, Boutelle MG, et al.. Association of seizures with cortical spreading depression and peri-infarct depolarisations in the acutely injured human brain. Clin Neurophysiol. 2008;119(9):1973–84.
  • Nakamura H, Strong AJ, Dohmen C, Sakowitz OW, Vollmar S, Sué M, et al.. Spreading depolarizations cycle around and enlarge focal ischaemic brain lesions. Brain. 2010;133(Pt 7):1994–2006.
  • Strong AJ, Hartings JA, Dreier JP. Cortical spreading depression: an adverse but treatable factor in intensive care? Curr Opin Crit Care. 2007;13(2):126–33.
  • Hadjikhani N, Sanchez Del Rio M, Wu O, Schwartz D, Bakker D, Fischl B, et al.. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc Natl Acad Sci USA. 2001;98(8):4687–92.
  • Olesen J, Larsen B, Lauritzen M. Focal hyperemia followed by spreading oligemia and impaired activation of rCBF in classic migraine. Ann Neurol. 1981;9(4):344–52.
  • Hartings JA, Rolli ML, Lu XC, Tortella FC. Delayed secondary phase of peri-infarct depolarizations after focal cerebral ischemia: relation to infarct growth and neuroprotection. J Neurosci. 2003;23(37):11602–10.
  • Hossmann KA. Periinfarct depolarizations. Cerebrovasc Brain Metab Rev. 1996;8(3):195–208.
  • Hartings JA, Watanabe T, Bullock MR, Okonkwo DO, Fabricius M, Woitzik J, et al.. Spreading depolarizations have prolonged direct current shifts and are associated with poor outcome in brain trauma. Brain. 2011;134(5):1529–40.
  • Feuerstein D, Manning A, Hashemi P, Bhatia R, Fabricius M, Tolias C, et al.. Dynamic metabolic response to multiple spreading depolarizations in patients with acute brain injury: an online microdialysis study. J Cerebr Blood Flow Metab. 2010;30(7):1343–55.
  • Piper RD, Lambert GA. Inhalational anesthetics inhibit spreading depression: relevance to migraine. Cephalalgia. 1996;16(2):87–92.
  • Kudo C, Nozari A, Moskowitz MA, Ayata C. The impact of anesthetics and hyperoxia on cortical spreading depression. Exp Neurol. 2008;212(1):201–6.
  • Alves HC, Valentim AM, Olsson IA, Antunes LM. Intraperitoneal anaesthesia with propofol, medetomidine and fentanyl in mice. Lab Anim. 2009;43(1):27–33.
  • Ayata C, Dunn AK, Gursoy OY, Huang Z, Boas DA, Moskowitz MA, et al.. Laser speckle flowmetry for the study of cerebrovascular physiology in normal and ischemic mouse cortex. J Cereb Blood Flow Metab. 2004;24(7):744–55.
  • Spitzer MW, Calford MB, Clarey JC, Pettigrew JD, Roe AW. Spontaneous and stimulus-evoked intrinsic optical signals in primary auditory cortex of the cat. J Neurophysiol. 2001;85(3):1283–98.
  • Lauritzen M, Dreier JP, Fabricius M, Hartings JA, Graf R, Strong AJ. Clinical relevance of cortical spreading depression in neurological disorders: migraine, malignant stroke, subarachnoid and intracranial hemorrhage, and traumatic brain injury. J Cerebr Blood Flow Metab. 2011;31(1):17–35.
  • Ba AM, Guiou M, Pouratian N, Muthialu A, Rex DE, Cannestra AF, et al.. Multiwavelength optical intrinsic signal imaging of cortical spreading depression. J Neurophysiol. 2002;88(5):2726–35.
  • Takano T, Tian GF, Peng W, Lou N, Lovatt D, Hansen AJ, et al.. Cortical spreading depression causes and coincides with tissue hypoxia. Nat Neurosci. 2007;10(6):754–62.
  • Shuttleworth CW. Use of NAD(P)H and flavoprotein autofluorescence transients to probe neuron and astrocyte responses to synaptic activation. Neurochem Int. 2010;56(3):379–86.
  • Dreier JP. The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease. Nat Med. 2011;17(4):439–47.
  • Hartings JA, Watanabe T, Dreier JP, Major S, Vendelbo L, Fabricius M. Recovery of slow potentials in AC-coupled electrocorticography: application to spreading depolarizations in rat and human cerebral cortex. J Neurophysiol. 2009;102(4):2563–75.
  • Lavine SD, Masri LS, Levy ML, Giannotta SL. Temporary occlusion of the middle cerebral artery in intracranial aneurysm surgery: time limitation and advantage of brain protection. J Neurosurg. 1997;87(6):817–24.
  • Lauritzen M, Jorgensen MB, Diemer NH, Gjedde A, Hansen AJ. Persistent oligemia of rat cerebral cortex in the wake of spreading depression. Ann Neurol. 1982;12(5):469–74.
  • Offenhauser N, Windmuller O, Strong AJ, Fuhr S, Dreier JP. The gamut of blood flow responses coupled to spreading depolarization in rat and human brain: from hyperemia to prolonged ischemia. Acta Neurochirurg Suppl. 2011;110(Pt 1):119–24.
  • Mayevsky A, Doron A, Manor T, Meilin S, Zarchin N, Ouaknine GE. Cortical spreading depression recorded from the human brain using a multiparametric monitoring system. Brain Res. 1996;740(1–2):268–74.
  • Rogatsky GG, Sonn J, Kamenir Y, Zarchin N, Mayevsky A. Relationship between intracranial pressure and cortical spreading depression following fluid percussion brain injury in rats. J Neurotrauma. 2003;20(12):1315–25.
  • Mayevsky A, Rogatsky GG. Mitochondrial function in vivo evaluated by NADH fluorescence: from animal models to human studies. Am J Physiol Cell Physiol. 2007;292(2):C615–40.
  • Zhou N, Gordon GR, Feighan D, MacVicar BA. Transient swelling, acidification, and mitochondrial depolarization occurs in neurons but not astrocytes during spreading depression. Cereb Cortex. 2010;20(11):2614–24.
  • Dietz RM, Weiss JH, Shuttleworth CW. Zn2+ influx is critical for some forms of spreading depression in brain slices. J Neurosci. 2008;28(32):8014–24.
  • Dreier JP, Windmuller O, Petzold G, Lindauer U, Einhaupl KM, Dirnagl U. Ischemia triggered by red blood cell products in the subarachnoid space is inhibited by nimodipine administration or moderate volume expansion/hemodilution in rats. Neurosurgery. 2002;51(6):1457–1465; discussion 1457–1465.
  • Allen GS, Ahn HS, Preziosi TJ, Battye R, Boone SC, Boone SC, et al.. Cerebral arterial spasm — a controlled trial of nimodipine in patients with subarachnoid hemorrhage. N Engl J Med. 1983;308(11):619–24.
  • Sakowitz OW, Kiening KL, Krajewski KL, Sarrafzadeh AS, Fabricius M, Strong AJ, et al.. Preliminary evidence that ketamine inhibits spreading depolarizations in acute human brain injury. Stroke. 2009;40(8):e519–22.
  • Ayata C, Jin H, Kudo C, Dalkara T, Moskowitz MA. Suppression of cortical spreading depression in migraine prophylaxis. Ann Neurol. 2006;59(4):652–61.
  • Yanamoto H, Xue JH, Miyamoto S, Nagata I, Nakano Y, Murao K, et al.. Spreading depression induces long-lasting brain protection against infarcted lesion development via BDNF gene-dependent mechanism. Brain Res. 2004;1019(1–2):178–88.

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