Reversal of neurobehavioral and neurochemical alterations in STZ-induced diabetic rats by FeTMPyP, a peroxynitrite decomposition catalyst and 1,5-Isoquinolinediol a poly(ADP-ribose) polymerase inhibitor

References

• Aragno M, Mastrocola R, Medana C, Restivo F, Catalano MG, Pons N, et al. Up-regulation of advanced glycated products receptors in the brain of diabetic rats is prevented by antioxidant treatment. Endocrinology. 2005;146:5561–7.
   PubMed Web of Science ®Google Scholar
• Biessels GJ, Kappelle AC, Bravenboer B, Erkelens DW, Gispen WH. Cerebral function in diabetes mellitus. Diabetologia. 1994;37:643–50.
   PubMed Web of Science ®Google Scholar
• Aragno M, Parola S, Brignardello E, Mauro A, Tamagno E, Manti R, et al. Dehydroepiandrosterone prevents oxidative injury induced by transient ischemia/reperfusion in the brain of diabetic rats. Diabetes. 2000;49:1924–31.
   PubMed Web of Science ®Google Scholar
• Aragno M, Parola S, Tamagno E, Brignardello E, Manti R, Danni O, et al. Oxidative derangement in rat synaptosomes induced by hyperglycaemia: restorative effect of dehydroepiandrosterone treatment. Biochem Pharmacol. 2000;60:389–95.
   PubMed Web of Science ®Google Scholar
• Mastrocola R, Restivo F, Vercellinatto I, Danni O, Brignardello E, Aragno M, et al. Oxidative and nitrosative stress in brain mitochondria of diabetic rats. J Endocrinol. 2005;187:37–44.
   PubMed Web of Science ®Google Scholar
• Kuhad A, Chopra K. Effect of sesamol on diabetes-associated cognitive decline in rats. Exp Brain Res. 2008;185:411–20.
   PubMed Web of Science ®Google Scholar
• Kuhad A, Sethi R, Chopra K. Lycopene attenuates diabetes-associated cognitive decline in rats. Life Sci. 2008;83:128.
   PubMed Web of Science ®Google Scholar
• Radi R, Peluffo G, Alvarez MN, Naviliat M, Cayota A. Unraveling peroxynitrite formation in biological systems. Free Radic Biol Med. 2001;30:463–88.
   PubMed Web of Science ®Google Scholar
• Marla SS, Lee J, Groves JT. Peroxynitrite rapidly permeates phospholipid membranes. Proc Natl Acad Sci U S A. 1997;94:14243–8.
   PubMed Web of Science ®Google Scholar
• Bartesaghi S, Valez V, Trujillo M, Peluffo G, Romero N, Zhang H, et al. Mechanistic studies of peroxynitrite-mediated tyrosine nitration in membranes using the hydrophobic probe Nt-BOC-L-tyrosine tert-butyl ester. Biochemistry. 2006;45:6813–25.
   PubMed Web of Science ®Google Scholar
• Szabo C. Multiple pathways of peroxynitrite cytotoxicity. Toxicol Lett. 2003;140:105–12.
   PubMed Web of Science ®Google Scholar
• Szabo C. Roles of poly (ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications. Pharmacol Res. 2005;52:60–71.
   PubMed Web of Science ®Google Scholar
• Negi G, Kumar A, Sharma SS. Concurrent targeting of nitrosative stress-PARP pathway corrects functional, behavioral and biochemical deficits in experimental diabetic neuropathy. Biochem Biophys Res Commun. 2010;391:102–6.
   PubMed Web of Science ®Google Scholar
• Irwin S. Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse. Psychopharmacology. 1968;13:222–57.
   PubMed Web of Science ®Google Scholar
• Mattsson JL, Spencer PJ, Albee RR. A performance standard for clinical and functional observational battery examinations of rats. Int J Toxicol. 1996;15:239–54.
   Web of Science ®Google Scholar
• Sharma SS, Srinivasan SK, Krishnamoorthy S, Kaushal AM, Bansal AK. Preclinical safety pharmacological studies on the amorphous formulation of celecoxib. Arzneim-Forsch. 2011;59:254–62.
   Web of Science ®Google Scholar
• Kumar P, Kaundal RK, More S, Sharma SS. Beneficial effects of pioglitazone on cognitive impairment in MPTP model of Parkinson's disease. Behav Brain Res. 2009;197:398–403.
   PubMed Web of Science ®Google Scholar
• Ohkawa H. Assay for lipid peroxide in animal tissue by thiobarbituric acid reaction. Anal Biochem. 1979;95:351–8.
   PubMed Web of Science ®Google Scholar
• Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265–75.
   PubMed Web of Science ®Google Scholar
• Nisselbaum JS, Green S. A simple ultramicro method for determination of pyridine nucleotides in tissues. Anal Biochem. 1969;27:212–7.
   PubMed Web of Science ®Google Scholar
• Negi G, Kumar A, Kaundal RK, Gulati A, Sharma SS. Functional and biochemical evidence indicating beneficial effect of Melatonin and Nicotinamide alone and in combination in experimental diabetic neuropathy. Neuropharmacology. 2010;58:585–92.
   PubMed Web of Science ®Google Scholar
• Lakshmana MK, Rao S, Dhingra NK, Ravikumar R, Meti BL, Raju TR. Chronic (−) deprenyl administration increases dendritic arborization in CA3 neurons of hippocampus and AChE activity in specific regions of the primate brain. Brain Res. 1998;796:38–44.
   PubMed Web of Science ®Google Scholar
• Rao BSS, Raju TR, Meti BL. Self-stimulation of lateral hypothalamus and ventral tegmentum increases the levels of noradrenaline, dopamine, glutamate, and AChE activity, but not 5-hydroxytryptamine and GABA levels in hippocampus and motor cortex. Neurochem Res. 1998;23:1053–9.
   PubMed Web of Science ®Google Scholar
• Bonnefont-Rousselot D. Glucose and reactive oxygen species. Curr Opin Clin Nutr Metab Care. 2002;5:561–8.
   PubMed Web of Science ®Google Scholar
• Lee AYW, Chung SSM. Contributions of polyol pathway to oxidative stress in diabetic cataract. FASEB J. 1999;13:23–30.
   PubMed Web of Science ®Google Scholar
• Ryle C, Leow CK, Donaghy M. Nonenzymatic glycation of peripheral and central nervous system proteins in experimental diabetes mellitus. Muscle Nerve. 1998;20:577–84.
   Web of Science ®Google Scholar
• Kumar JS, Menon VP. Effect of diabetes on levels of lipid peroxides and glycolipids in rat brain. Metabolism. 1993;42:1435–9.
   PubMed Web of Science ®Google Scholar
• Baynes JW, Thorpe SR. Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes. 1999;48:1–9.
   PubMed Web of Science ®Google Scholar
• Murray J, Taylor SW, Zhang B, Ghosh SS, Capaldi RA. Oxidative damage to mitochondrial complex I due to peroxynitrite. J Biol Chem. 2003;278:37223–30.
   PubMed Web of Science ®Google Scholar
• Massaad CA, Klann E. Reactive oxygen species in the regulation of synaptic plasticity and memory. Antioxid Redox Signal. 2011;14:2013–54.
   PubMed Web of Science ®Google Scholar
• Sharma SS, Munusamy S, Thiyagarajan M, Kaul CL. Neuroprotective effect of peroxynitrite decomposition catalyst and poly (adenosine diphosphate-ribose) polymerase inhibitor alone and in combination in rats with focal ischemia. J Neurosurg. 2004;101:669–75.
   PubMed Web of Science ®Google Scholar
• Arora M, Kumar A, Kaundal RK, Sharma SS. Amelioration of neurological and biochemical deficits by peroxynitrite decomposition catalysts in experimental diabetic neuropathy. Eur J Pharmacol. 2008;596:77–83.
   PubMed Web of Science ®Google Scholar
• Drel VR, Xu W, Zhang J, Pavlov IA, Shevalye H, Slusher B, et al. Poly (adenosine 5-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy. Endocrinology. 2009;150:5273–83.
   PubMed Web of Science ®Google Scholar
• Chaitanya GV, Steven AJ, Babu PP. PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration. Cell Commun Signal. 2010;8:31–41.
   PubMed Web of Science ®Google Scholar
• Kamboj SS, Chopra K, Sandhir R. Neuroprotective effect of N-acetylcysteine in the development of diabetic encephalopathy in streptozotocin-induced diabetes. Metab Brain Dis. 2008;23:427–43.
   PubMed Web of Science ®Google Scholar
• Sales I, Freitas R, Saldanha G, Souza G, Freitas R. Choline acetyltransferase and acetylcholinesterase activities are reduced in rat striatum and frontal cortex after pilocarpine-induced seizures. Neurosci Lett. 2010;469:81–3.
   PubMed Web of Science ®Google Scholar
• Das A, Rai D, Dikshit M, Palit G, Nath C. Nature of stress: differential effects on brain acetylcholinesterase activity and memory in rats. Life Sci. 2005;77:2299–311.
   PubMed Web of Science ®Google Scholar
• Sandhir R, Julka D, Gill K. Lipoperoxidative damage on lead exposure in rat brain and its implications on membrane bound enzymes. Pharmacol Toxicol. 2009;74:66–71.
   Google Scholar
• Ashok kumar N, Pari L, Ramkumar KM. N-Benzoyl-D-phenylalanine attenuates brain acetylcholinesterase in neonatal streptozotocin-diabetic rats. Basic Clin Pharm Toxicol. 2006;99:246–50.
   PubMed Web of Science ®Google Scholar
• Tsakiris S. Effects of l-phenylalanine on acetylcholinesterase and Na(+)/K(+)-ATPase activities in adult and aged rat brain. Mech Ageing Dev. 2001;122:491–501.
   PubMed Web of Science ®Google Scholar
• Riedel G, Reymann KG. Metabotropic glutamate receptors in hippocampal long-term potentiation and learning and memory. Acta Physiol Scand. 1996;157:1–19.
   PubMedGoogle Scholar
• Cruz-Morales SE, Quirarte GL, Diaz del Guante MA, Prado-Alcalá RA. Effects of GABA antagonists on inhibitory avoidance. Life Sci. 1993;53:1325–30.
   PubMed Web of Science ®Google Scholar
• Flood JF, Morley JE, Roberts E. Memory-enhancing effects in male mice of pregnenolone and steroids metabolically derived from it. Proc Natl Acad Sci U S A. 1992;89:1567–71.
   PubMed Web of Science ®Google Scholar
• Brioni JD. Role of GABA during the multiple consolidation of memory. Drug Dev Res. 2004;28:3–27.
   Google Scholar
• Sickmann HM, Waagepetersen HS, Schousboe A, Benie AJ, Bouman SD. Brain glycogen and its role in supporting glutamate and GABA homeostasis in a type 2 diabetes rat model. Neurochem Int. 2012;60:267–75.
   PubMed Web of Science ®Google Scholar