Advanced search
Publication Cover
Journal of Chemotherapy Volume 26, 2014 - Issue 5
Submit an article Journal homepage
91
Views
3
CrossRef citations to date
0
Altmetric
Brief Communications

Pharmacokinetics of a polyene antifungal agent, liposomal amphotericin B (L-AMB), in a severely burned patient

Junichi SasakiDepartment of Emergency and Critical Care MedicineSchool of Medicine, Keio University, Tokyo, JapanCorrespondence[email protected]
,
Kana MatsumotoDepartment of Clinical PharmaceuticsFaculty of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts, Kyoto, Japan
,
Seitaro FujishimaDepartment of Emergency and Critical Care MedicineSchool of Medicine, Keio University, Tokyo, Japan
,
Kunihiko MoritaDepartment of Clinical PharmaceuticsFaculty of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts, Kyoto, Japan
&
Shingo HoriDepartment of Emergency and Critical Care MedicineSchool of Medicine, Keio University, Tokyo, Japan
Pages 312-314 | Published online: 06 Dec 2013

References

  • Sasaki J, Yamanouchi S, Kudo D, Endo T, Nomura R, Takuma K, et al. Micafungin concentrations in the plasma and burn eschar of severely burned patients. Antimicrob Agents Chemother. 2012;56:1113–5.
  • Sasaki J, Yamanouchi S, Sato Y, Abe S, Shinozawa Y, Kishino S, et al. Penetration of micafungin into the burn eschar in patients with severe burns. Eur J Drug Metab Pharmacokinet. 2014;39:93–7.
  • Moore EC, Padiglione AA, Wasiak J, Paul E, Cleland H. Candida in burns: risk factors and outcomes. J Burn Care Res. 2010;31:257–63.
  • Jaehde U, Sörgel F. Clinical pharmacokinetics in patients with burns. Clin Pharmacokinet. 1995;29:15–28.
  • Weinbren MJ. Pharmacokinetics of antibiotics in burn patients. J Antimicrob Chemother. 1999;44:319–27.
  • Pea F, Viale P, Furlanut M. Antimicrobial therapy in critically ill patients: a review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability. Clin Pharmacokinet. 2005;44:1009–34.
  • Blanchet B, Jullien V, Vinsonneau C, Tod M. Influence of burns on pharmacokinetics and pharmacodynamics of drugs used in the care of burn patients. Clin Pharmacokinet. 2008;47:635–54.
  • Boucher BA, King SR, Wandschneider HL, Hickerson WL, Hanes SD, Herring VL, et al. Fluconazole pharmacokinetics in burn patients. Antimicrob Agents Chemother. 1998;42:930–33.
  • Santos SR, Campos EV, Sanches C, Gomez DS, Ferreira MC. Fluconazole plasma concentration measurement by liquid chromatography for drug monitoring of burn patients. Clinics 2010;65:237–43.
  • Ha JF, Italiano CM, Heath CH, Shih S, Rea S, Wood FM. Candidemia and invasive candidiasis: a review of the literature for the burns surgeon. Burns. 2011;37:181–95.
  • Takemoto K, Yamamoto Y, Ueda Y. Evaluation of antifungal pharmacodynamic characteristics of AmBisome against Candida albicans. Microbiol Immunol. 2006;50:579–86.
  • Watanabe A, Matsumoto K, Igari H, Uesato M, Yoshida S, Nakamura Y, et al. Comparison between concentrations of amphotericin B in infected lung lesion and in uninfected lung tissue in a patient treated with liposomal amphotericin B (AmBisome). Int J Infect Dis. 2010;14S:e220–23.
  • Regules JA, Andes D, Akers KS, D’avignon LC, Murray CK, Chung KC, et al. Pharmacokinetics of voriconazole in patients with severe burns. 48th ICAAC/46th IDSA annual meeting Abst A-021; 2008 Oct 25–28; Washington DC, USA.
  • Hartsel SC, Baas B, Bauer E, Foree LT Jr, Kindt K, Preis H, et al. Heat-induced superaggregation of amphotericin B modifies its interaction with serum proteins and lipoproteins and stimulation of TNF-alpha. J Pharm Sci. 2001;90:124–33.
  • Bekersky I, Fielding RM, Dressler DE, Lee JW, Buell DN, Walsh TJ. Plasma protein binding of amphotericin B and pharmacokinetics of bound versus unbound amphotericin B after administration of intravenous liposomal amphotericin B (AmBisome) and amphotericin B deoxycholate. Antimicrob Agents Chemother. 2002;46:834–40.
  • Proffitt RT, Adler-Moore J, Fujii G, Satorius A, Lee MJA, Bailey A. Stability and mode of action of Ambisome® (Liposomal Amphotericin B). J Controlled Release. 1994;28:342–3.
  • Izumikawa K, Kohno S. Lipid based formulations of amphotericin B. Kokyū. 2006;25:157–62.
  • Juliano RL. Factor affecting the clearance kinetics and tissue distribution of liposomes, microspheres and emulsions. Adv Drug Delivery Rev. 1988;2:31–54.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.