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Paediatrics and International Child Health Volume 35, 2015 - Issue 1
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Original Research Articles

Treatment of childhood tuberculosis: caregivers’ practices and perceptions in Cape Town, South Africa

Sabine BélardDepartment of Paediatrics and Child HealthRed Cross War Memorial Children’s Hospital, and;Institute of Infectious Disease and Molecular MedicineUniversity of Cape Town, South Africa;Centre for Tropical Medicine and Travel Medicine, Division of Internal Medicine, Academic Medical Centre, University of Amsterdam,The Netherlands
,
Washiefa IsaacsDepartment of Paediatrics and Child HealthRed Cross War Memorial Children’s Hospital, and
,
Faye BlackDepartment of Paediatrics and Child HealthRed Cross War Memorial Children’s Hospital, and
,
Lindy BatemanDepartment of Paediatrics and Child HealthRed Cross War Memorial Children’s Hospital, and
,
Lucia MadoloDepartment of Paediatrics and Child HealthRed Cross War Memorial Children’s Hospital, and
,
Jacinta MunroDepartment of Paediatrics and Child HealthRed Cross War Memorial Children’s Hospital, and
,
Lesley WorkmanDepartment of Paediatrics and Child HealthRed Cross War Memorial Children’s Hospital, and
,
Martin P. GrobuschInstitute of Infectious Disease and Molecular MedicineUniversity of Cape Town, South Africa;Centre for Tropical Medicine and Travel Medicine, Division of Internal Medicine, Academic Medical Centre, University of Amsterdam,The Netherlands
&
Heather J. ZarDepartment of Paediatrics and Child HealthRed Cross War Memorial Children’s Hospital, and;Institute of Infectious Disease and Molecular MedicineUniversity of Cape Town, South AfricaCorrespondence[email protected]
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Pages 24-28 | Received 03 Dec 2013, Accepted 24 Jun 2014, Published online: 18 Jul 2014

References

  • World Health Organization. Roadmap for childhood tuberculosis: towards zero deaths. Geneva: WHO, 2013. Available from: http://www.theunion.org/images/stories/news/ChildhoodTB-Roadmap_Final_1October2013.pdf
  • Marais BJ, Hesseling AC, Gie RP, Schaaf HS, Beyers N. The burden of childhood tuberculosis and the accuracy of community-based surveillance data. Int J Tuberc Lung Dis. 2006;10:259–63.
  • Zar HJ, Pai M. Childhood tuberculosis – a new era. Paediatr Respir Rev. 2011;12:1–2.
  • Craig SR, Adams LV, Spielberg SP, Campbell B. Pediatric therapeutics and medicine administration in resource-poor settings: a review of barriers and an agenda for interdisciplinary approaches to improving outcomes. Soc Sci Med. 2009;69:1681–90.
  • Zar HJ, Workman L, Isaacs W, Munro J, Black F, Eley B, et al. Rapid molecular diagnosis of pulmonary tuberculosis in children using nasopharyngeal specimens. Clin Infect Dis. 2012;55:1088–95.
  • Department of Health, South Africa. National Tuberculosis Management Guidelines, 2009.
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  • Pasipanodya JG, McIlleron H, Burger A, Wash PA, Smith P, Gumbo T. Serum drug concentrations predictive of pulmonary tuberculosis outcomes. J Infect Dis. 2013;208:1464–73.
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  • Donald PR, Ahmed A, Burman WJ, Cotton MF, Graham SM, Mendel C, et al. Requirements for the clinical evaluation of new anti-tuberculosis agents in children. Int J Tuberc Lung Dis. 2013;17:794–9.
  • Best BM, Capparelli EV, Diep H, Rossi SS, Farrell MJ, Williams E, et al. Pharmacokinetics of lopinavir/ritonavir crushed versus whole tablets in children. J Acquir Immun Defic Syndr. 2011;58:385–91.
  • Notterman DA, Nardi M, Saslow JG. Effect of dose formulation on isoniazid absorption in two young children. Pediatrics. 1986;77:850–2.
  • Kurth F, Belard S, Adegnika AA, Gaye O, Kremsner PG, Ramharter M. Do paediatric drug formulations of artemisinin combination therapies improve the treatment of children with malaria? A systematic review and meta-analysis. Lancet Infect Dis. 2010;10:125–32.
  • Waning B, Diedrichsen E, Jambert E, Barnighausen T, Li Y, Pouw M, et al. The global pediatric antiretroviral market: analyses of product availability and utilization reveal challenges for development of pediatric formulations and HIV/AIDS treatment in children. BMC Pediatr. 2010;10:74.

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