PLASMA VITAMIN C FOR PREDICTING CARDIOVASCULAR DISEASE: MORE THAN A NUTRITIONAL BIOMARKER

REFERENCES

• Kris-Etherson PM, Lichtenstein AH, Howard By, Steinberg D, Witztum JL for the Nutrition Committee of the American Heart Association Council on Nutrition, Physical Activity, and Metabolism. Antioxidant vitamin supplements and cardiovas-cular disease. Circulation 2004;110:637–41.
   Web of Science ®Google Scholar
• Nyyssonen K, Parviainen MT, Salonen R, Tuomilehto J, Salonen JT. Vitamin C deficiency and risk of myocardial infarction: Pro-spective population study of men from eastern Finland. BMJ 1997;314:634–8.
   PubMed Web of Science ®Google Scholar
• Deicher R, Ziai F, Bieglmayer C, Schillinger M, Hörl WH. Low total vitamin C plasma level is a risk factor for cardiovascu-lar morbidity and mortality in hemodialysis patients. J Am Soc Nephrol 2005;16:1811–8.
   PubMed Web of Science ®Google Scholar
• Myint PK, Luben RN, Welch AA, Bingham SA, Wareham NJ, Khaw K-T. Plasma vitamin C concentrations predict risk of in-cident stroke over 10 y in 20649 participants of the European Prospective Investigation into Cancer-Norfolk prospective population study. Am] Clin Nutr 2008;87:64–9.
   PubMed Web of Science ®Google Scholar
• Padayatty Si, Levine M. Fruit and vegetables: think variety, go ahead, eat! (editorial) Am] Clin Nutr 2008;87: 5–7.
   PubMed Web of Science ®Google Scholar
• Hampl JS, Taylor CA, Johnston CS. Vitamin C Deficiency and Depletion in the United States: The Third National Health and Nutrition Examination Survey, 1988 to 1994. Am J Public Health 2004;94:870–5.
   PubMed Web of Science ®Google Scholar
• Delanghe JR, Langlois MR, De Buyzere ML, Torck M. Vitamin C deficiency and scurvy are not only a dietary problem but are codetermined by the haptoglobin polymorphism. Clin Chem 2007;53:1397–400.
   PubMed Web of Science ®Google Scholar
• Langlois M, Duprez D, Delanghe J, De Buyzere M, Clement DL. Serum vitamin C concentration is low in peripheral arterial disease and is associated with inflammation and severity of atherosclerosis. Circulation 2001103: 1863–81.
   Google Scholar
• Engstrom G, Lind P, Hedblad B, Stavenow L, Janzon L, Lindgärde F. Effects of cholesterol and inflammation-sensitive plasma proteins on incidence of myocardial infarction and stroke in men. Circulation 2002;105:2632–7.
   PubMed Web of Science ®Google Scholar
• Everett BM, Kurth T, Buring JE, Ridker PM. The relative strength of C-reactive protein and lipid levels as determinants of isch-emic stroke compared with coronary heart disease in women. J Am Coll Card 2006;48:2235–42.
   PubMed Web of Science ®Google Scholar
• Devriese AS, Borrey D, Mahieu E, et al. Oral vitamin C admin-istration increases lipid oxidation in hemodialysis patients. Nephron Clin Pract 2008;108:28–34.
   Web of Science ®Google Scholar
• Lee D-H, Folsom AR, Harnack L, Halliwell B, Jacobs Jr DR. Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes? Am] Clin Nutr 2004;80: 1194–200.
   PubMed Web of Science ®Google Scholar
• Livrea MA, Tesoriere L, Pintaudi AM et al. Oxidative stress and antioxidant status in I3-thalassemia major: iron overload and depletion of lipid-soluble antioxidants. Blood 1996;88:3608–14.
   PubMed Web of Science ®Google Scholar
• Langlois MR, Delanghe JR, De Buyzere ML, Bernard DR, Ouyang J. Effect of haptoglobin on the metabolism of vitamin C. Am] Clin Nutr 1997;66:606–10.
   PubMed Web of Science ®Google Scholar
• Na N, Delanghe JR, Taes YE, Torck M, Baeyens WR, Ouyang J. Serum vitamin C concentration is influenced by haptoglobin polymorphism and iron status in Chinese. Clin Chim Acta 2006;365:319–24.
   PubMed Web of Science ®Google Scholar
• Van Vlierberghe H, Langlois M, Delanghe J. Haptoglobin poly-morphisms and iron homeostasis in health and in disease. Clin Chim Acta 2004;345:35–42.
   PubMed Web of Science ®Google Scholar
• Chaichana KL, Levy AP, Miller-Lotan R, Shakur S, Tamargo RJ. Haptoglobin 2-2 genotype determines chronic vasospasm after experimental subarachnoid hemorrhage. Stroke 2007;38:3266–71.
   PubMed Web of Science ®Google Scholar
• Sadrzadeh SM, Saffari Y, Bozorgmehr J. Haptoglobin pheno-types in epilepsy. Clin Chem 2004;50:1095–7.
   PubMed Web of Science ®Google Scholar
• Saccucci P, Verdecchia M, Piciullo A et al. Convulsive disorder and genetic polymorphism. Association of idiopathic general-ized epilepsy with haptoglobin polymorphism. Neurogenetics 2004;5:245–8.
   Web of Science ®Google Scholar
• Sadrzadeh SMH, Eaton JW. Hemoglobin-mediated oxidant damage to the central nervous system requires endogenous ascorbate. J Clin Invest 1988;82:1510–5.
   PubMed Web of Science ®Google Scholar
• Levy AP, Levy JE, Kalet-Litman S et al. Haptoglobin genotype is a determinant of iron, lipid peroxidation and macrophage ac-cumulation in the atherosclerotic plaque. Arterioscler Thromb Vasc Biol 2007;27:134–40.
   PubMed Web of Science ®Google Scholar
• Milman U, Blum S, Shapira C et al. Vitamin E supplementation reduces cardiovascular events in a subgroup of middle-aged individuals with both type 2 diabetes mellitus and the hapto-globin 2-2 genotype.A prospective double-blinded clinical Arterioscler Thromb Vasc Biol 2008;28:341–7.
   PubMed Web of Science ®Google Scholar
• Willcox BJ, Curb DJ, Rodriguez BL. Antioxidants in cardiovascu-lar health and disease: key lessons from epidemiological stud-ies. Am] Cardiol 2008;101(Suppl) :75D–86D.
   Google Scholar
• Li Y, Schellhorn HE. New developments and novel therapeutic perspectives for vitamin C. J Nutr 2007;137:2171–84.
   PubMed Web of Science ®Google Scholar