Induction Chemotherapy to Weekly Paclitaxel Concurrent with Curative Radiotherapy in Stage IV (M0) Unresectable Head and Neck Squamous Cell Carcinoma: a Dose Escalation Study

REFERENCES

• Posner MR, Glisson B, Frenette G, et al. Multicenter phase I-II trial of docetaxel, cisplatin, and fluorouracil induction chemotherapy for patients with locally advanced squamous cell cancer of the head and neck. J Clin Oncol 2001; 19: 1096–1104.
   PubMed Web of Science ®Google Scholar
• Machtay M, Rosenthal DI, Hershock D, et al. Organ Preservation Therapy Using Induction Plus Concurrent Chemoradiation for Advanced Resectable Oropharyngeal Carcinoma: A University of Pennsylvania Phase II Trial. J Clin Oncol 2002; 20: 3964–3971.
   PubMed Web of Science ®Google Scholar
• Kies MS, Haraf DJ, Athanasiadis I, et al. Induction chemotherapy followed by concurrent chemoradiation for advanced head and neck cancer: Improved disease control and survival. J Clin Oncol 1998; 16: 2715–2721.
   PubMed Web of Science ®Google Scholar
• Mantz CA, Vokes EE, Stenson K, et al. Induction chemotherapy followed by concomitant chemoradiotherapy in the treatment of locoregionally advanced oropharyngeal can-cer. Cancer J 2001; 7: 140–148.
   PubMed Web of Science ®Google Scholar
• Geard CR, Jone JM, Schiff PB. Taxol and radiation. J Nati Cancer Inst 1993; 5: 89–94.
   Google Scholar
• Choy H, Rodriguez FF, Koester S, et al. Investigation of taxol as a potential radiation sensitizer. Cancer 1993; 71: 3774–3778.
   PubMed Web of Science ®Google Scholar
• Safran H, King T, Choy H, et al. p53 mutations do not predict response to paclitaxel/radiation for non-small cell lung cancer. Cancer 1996; 78: 1209-1216.
   Google Scholar
• Milas L, Hunter NR, Mason KA, et al. Role of reoxy-genation in induction of enhancement of tumor radioresponse by paclitaxel. Caner Res 1995; 55: 3564–3568.
   PubMed Web of Science ®Google Scholar
• Maisano R, Adamo V, Pergolizzi S, et al. Concurrent Carboplatin and Radiotherapy in the Treatment of Squamous Cell Carcinoma of the Head and Neck, Stage IV. Preliminary data of a phase II Study. J Chemother 1995; 7: 549–553.
   Google Scholar
• Russi EG, Pergolizzi S, Spadaro P, et al. Prevention of oral mucositis during radiation therapy of head and neck can-cer (preliminary study). Giorn It Oncol 1992; 2: 78–84.
   Google Scholar
• Spadaro P, Pergolizzi S, Russi EG, et al. Prophylaxis of chemotherapy-radiotherapy induced mucositis or oral fungal infection with vitamin E + Vitamin A and Fluconazolo. Eur J Cancer 1991; 27 (2): S288.
   Google Scholar
• Calais G, Alfonsi M, Bardet E, et al. Randomized trial of radiation therapy versus concomitant chemoradiotherapy and radiation therapy for advanced-stage oropharynx carcino-ma. J Nati Cancer Inst 1999; 91: 2081–2086.
   PubMed Web of Science ®Google Scholar
• Bourhis J, Pignon JP. Meta-analyses in head and neck squamous cell carcinoma. What is the role of chemotherapy? Hematol Oncol Clin North Am 1999; 13: 769–775.
   PubMed Web of Science ®Google Scholar
• Wendt TG, Grabenbauer CC, Rodel CM, et al. Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: a randomized multicenter study. J Clin Oncol 1998; 16: 1318–1324.
   PubMed Web of Science ®Google Scholar
• Garden AS, Glisson BS, Ang KK, et al. Phase I/II Trial of Radiation With Chemotherapy “Boost” for Advanced Squamous Cell Carcinomas of the Head and Neck: Toxicities and Responses. J Clin Oncol 1999; 17: 2390–2395.
   PubMed Web of Science ®Google Scholar
• Forastiere AA, Metch B, Schuller DE, et al. Randomized comparison of cisplatin plus fluorouracil and car-boplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: A Southwest Oncology Group study. J Clin Oncol 1992; 10: 1245–1251.
   PubMed Web of Science ®Google Scholar
• Jacobs C, Lyman G, Velez-Garcia E, et al. A phase III randomized study comparing cisplatin and fluorouracil as sin-gle agents and in combination for advanced squamous cell carcimona of the head and neck. J Clin Oncol 1992; 10: 257–263.
   PubMed Web of Science ®Google Scholar
• Murphy B, Li Y, Cella D, et al. Phase III study compar-ing cisplatin (C) and 5-fluorouracil (F) versus cisplatin and paclitaxel (T) in metastatic/recurrent head and neck cancer (MHNC). Proc Am Soc Clin Oncol 2001; 20: 894.
   Google Scholar
• Flood WA, Lee DJ, Trotti A, et al. A phase I study of weekly paclitaxel and cisplatin concurrent with postoperative radiation therapy for treatment of high-risk patients with squa-mous cell cancer of the head and neck. Proc Am Soc Clin Oncol 1996; 15: 314.
   Google Scholar
• Hoffmann W, Belka C, Schmidberg H, et al. Radiotherapy and concomitant weekly 1-hour infusion of paclitaxel in the treatment of head and neck cancer. Results of a phase I study. Int J Radiat Oncol Biol Phys 1997; 38: 691–696.
   PubMed Web of Science ®Google Scholar
• Machtay M, Rosenthal DI, Algazy KM, et al. Pilot study of organ preservation multimodality therapy for locally advanced resectable oropharyngeal carcinoma. Am J Clin Oncol 2000; 23: 509–515.
   PubMed Web of Science ®Google Scholar
• Plasswilm L, Kirschner M, Sauer R. Concurrent Taxol and split-course accelerated radiotherapy for advanced head and neck cancer. Strahlenther Onkol 1996; 172: 573–579.
   PubMedGoogle Scholar
• Suntharalingam M, Haas ML, Conley BA, et al. The use of carboplatin and paclitaxel with daily radiotherapy in patients with locally advanced squamous cell carcinomas of the head and neck. Int J Radiat Oncol Biol Phys 2000; 47: 49–56.
   PubMed Web of Science ®Google Scholar
• Conley B, Jacobs M, Suntharalingam M, et al. A pilot trial of Paclitaxel, carboplatin, and concurrent radiotherapy for unresectable squamous cell carcinoma of the head and neck. Semin Oncol 1997; 24 (2): 78–80.
   Google Scholar
• Eckhardt A, Wildfang I, Karstens J. Simultaneous radiochemotherapy with Taxol/carboplatin in advanced opera-ble head and neck tumors. Preliminary results. Strahlenther Onkol 1999; 175 (3): 11–13.
   PubMed Web of Science ®Google Scholar
• Chougule P, Akhtar M, Akerley W et al. Chemoradiotherapy for advanced inoperable head and neck cancer. A phase II study. Semin Radiat Oncol 1999; 9 (1): 58–63.
   Google Scholar