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Plenary Sessions

New Microtubule / Tubulin-Targeted Anticancer Drugs and Novel Chemotherapeutic Strategies

  • Hyams J, Lloyd C, Microtubules, John Wiley and Sons, Inc., New York, 1994: 59-84.
  • Jordan MA. Mechanism of action of antitumor drugs that interact with microtubules and tubulin. Curr Med Chem-Anti-Cancer Agents 2002; 2: 1–17.
  • Jordan MA, Wilson L. Microtubules as targets for anti-cancer drugs. Nature Rev Cancer 2004; 4: 253–265.
  • Giannakakou P, Sackett D, Fojo T. Tubulin/micro-tubules: still a promising target for new chemotherapeutic agents. J Natl Cancer Inst 2000; 92: 182–183.
  • Cassimeris L. The oncoprotein 18/stathmin family of microtubule destabilizers. Curr Opin Cell Biol 2002; 14: 18–24.
  • Wilson L, Panda D, Jordan MA. Modulation of micro-tubule dynamics by drugs: a paradigm for the actions of cellu-lar regulators. Cell Struct Function 1999; 24: 329–335.
  • Derry WB, Wilson L, Jordan MA. Substoichiometric binding of taxol suppresses microtubule dynamics. Biochemistry 1995; 34: 2203–2211.
  • Nogales E. Structural insights into microtubule function, Annu Rev Biophys Biomol Struct 2001; 30: 397–420.
  • Honore S, Kamath K, Brauger D et al. Synergistic sup-pression of microtubule dynamics by discodermolide and pacli-taxel in non-small cell lung cancer. Cancer Res. In Press, 2004.

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