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Original Articles

Succimer (Meso-2,3-Dimercaptosuccinic Acid (DMSA)) Treatment of Andean Children with Environmental Lead Exposure

Pages 164-168 | Published online: 19 Jul 2013

References

  • Adams RD, Victor M ( eds). Principles of Neurology. New York: McGraw-Hill, 1993.
  • Anderson AC, Pueschel SM, Linakis JG. Pathophysiology of lead poisoning. In: Pueschel SM, Linakis JG, Anderson AC ( eds). Lead Poisoning in Childhood. Baltimore, MD: Paul H. Brookes, 1996: 75-96.
  • Shannon MW, Townsend MK. Adverse effects of reduced-dose D-penicillamine in children with mild-to-moderate lead poison-ing. Ann Pharmacother. 2000; 34: 15–8.
  • Rifai N, Cohen G, Wolf M, et al. Incidence of lead poisoning in young children from inner-city, suburban and rural communi-ties, Ther Drug Monit. 1993; 15: 71–4.
  • National Research Council. Measuring lead exposure in infants, children, and other sensitive populations. Washington, DC: National Academy Press, 1993.
  • Brody DJ, Pirkle JL, Kramer RA, et al. Blood lead levels in the US population. Phase 1 of the Third National Health and Nutri-tion Examination Survey (NHANES III, 1988 to 1991), JAMA. 1994; 272: 227–83.
  • Aschengrau A, Beiser A, Bellinger D, Copenhafer D, Weitzman M. Residential lead-based-paint hazard remediation and soil lead abatement: their impact among children with mildly ele-vated blood lead levels. Am J Public Health. 1997; 87: 1698–702.
  • Matte TD, Figueroa PJ, Ostrowski S, et al. Lead poisoning among household members exposed to lead-acid battery repair shops in Kingston, Jamaica. Int J Epidemiol. 1989; 18: 874–81.
  • Counter SA, Buchanan LH, Ortega F, Amarisiriwardena C, Hu H. Environmental lead contamination and pediatric lead intox-ication in an Ecuadorian Andean village, Int J Occup Environ Health. 2000; 6: 169–76.
  • Needleman HL, Gunnoe C, Leviton A, et at. Deficits in psycho-logic and classroom performance of children with elevated dentin lead levels. N Engl J Med. 1979; 300: 689–95.
  • Bellinger D, Leviton A, Waternaux C, Needleman HL, Rabi-nowitz M. Longitudinal analysis of prenatal and postnatal lead exposure and early cognitive development. N Engl J Med. 1987; 316: 1037–43.
  • Dietrich KN, Succop PA, Bornschein RL, et at. Lead exposure and neurobehavioral development in later infancy. Environ Health Perspect. 1990; 89: 13–9.
  • Dietrich RN, Succop PA, Berger OG, Keith RW. Lead exposure and the central auditory processing abilities and cognitive development of urban children: the Cincinnati lead study cohort at age 5 years. Neurotoxicol Teratol. 1992; 14: 51–6.
  • Shannon MW, Graef JW. Lead intoxication in infancy. Pedi-atrics. 1992; 89: 87–90.
  • Isselbacher KJ, Braunwald E, Wilson JD, Martin JB, Fauci AS, Kasper DL (eds). Harrison's Principles of Internal Medicine. 13th ed. New York: McGraw-Hill 1994.
  • Banks EC, Ferretti LE, Shucard DW. Effects of low level lead exposure on cognitive function in children: a review of behav-ioral, neuropsychological and biological evidence. Neuroto3d-cology. 1997; 18: 237–81.
  • Pirkle JL, Brody, DJ, Gunter EW, et al. The decline in blood lead levels in the United States. JAMA. 1994; 272: 284–91.
  • Ruff HA, Markowitz ME, Bijur PE, Rosen JF. Relationships among blood lead levels, iron deficiency, and cognitive devel-opment in two year-old children. Environ Health Perspect. 1996; 104: 180–5.
  • Wasserman GA, Liu X, Popavac D, et al. The Yugoslavia prospec-tive lead study: contributions of prenatal and postal lead expo-sure to early intelligence. Neurotoxicol Teratol. 2000; 22: 811–8.
  • Counter SA, Buchanan LH, Rosas HD, Ortega F. Neurocogni-tive effects of chronic elevated blood lead levels in Andean chil-dren. J Neurol Sci. 1998; 160: 47–53.
  • Counter SA, Buchanan LH, Ortega F, Rifia N., Blood lead and hemoglobin levels in Andean children with chronic lead intox-ication. Neurotoxicology. 2000; 21: 301–8.
  • Wegmann K. Chelation therapy to treat lead toxicity in chil-dren. Minn Med. 1992; 75: 25–7.
  • Graziano JH. Conceptual and practical advances in the meas-urement and clinical management of lead toxicity. Neurotoxi-cology. 1993; 14: 219–23.
  • Liebelt EL, Shannon MW. Oral chelators for childhood lead poisoning. Pediatr Ann. 1994; 23: 616–9.
  • Chisolm 11. Mobilization of lead by calcium disodium edetate: a reappraisal. Arch Pediatr Med. 1987; 141: 1256-7.
  • Chisolm JJ. Evaluation of the potential role of chelation therapy in treatment of low to moderate lead exposures. Environ Health Perspect. 1990; 89: 67–74.
  • Lin JL, Ho HH, Yu CC. Chelation therapy for patients with ele-vated body lead burden and progressive renal insufficiency. A randomized, controlled trial. Ann Intern Med. 1999; 130: 7–13.
  • Chisolm JJ. BAL, EDTA, DMSA and DMPS in the treatment of lead poisoning in children. J Pharmacol Clin Toxicol. 1992: 30: 493–504.
  • Glotzer DE. The current role of 2,3-dimercaptosuccinic acid (DMSA) in the management of childhood lead poisoning. Drug Saf. 1993; 9: 85–92.
  • Anderson RL, Super DM. Short-term efficacy of oral dimercap-tosuccinic acid in children with low to moderate lead intoxica-tion. Pediatrics. 1995; 96: 683–7.
  • Besunder JB, Super DM, Anderson RL Comparison of dimer-captosuccinic acid and calcium disodium ethylenediaminete-traacetic acid versus dimercaptopropanol and ethylenedi-aminetetraacetic acid in children with lead poisoning. J Pediatr. 1997; 130: 966–71.
  • O'Connor ME, Rich D. Children with moderately elevated lead levels: is chelation with DMSA helpful? Clin Pediatr. 1999; 38: 325–31.
  • Bornschein RL, Chisolm JJ, Damokosh Al, et al. Safety and effi-cacy of succimer in toddlers with blood lead levels of 20-44 pg/dL. Treatment of lead exposed children (TLC) trial group. Pediatr Res. 2000; 48: 593–9.
  • Cremin JJ, Luck M, Laughlin N, Smith DR. Efficacy of succimer chelation for reducing brain lead in a primate model of human lead exposure. Toxicol Appl Pharmacol. 1999; 161: 283–93.
  • Smith D, Bayer L, Strupp BJ. Efficacy of succimer chelation for reducing brain Pb levels in a rodent model. Environ Res. 78: 1998; 168–76.
  • Smith DR, Calacsan C, Woolard D, Luck M, Cremin J, Laughlin NE. Succimer and the urinary excretion of essential elements in a primate model of childhood lead exposure. Toxicol Sci. 2000; 54: 473–80.
  • Chisolm JJ. Safety and efficacy of meso-2,3-dimercaptosuccinic acid (DMSA) in children with elevated blood lead concentra-tions. J Pharmacol Clin Toxicol. 38: 2000; 365–75.

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