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Original Article

Efficacy, tolerability, and parent reported outcomes for cefdinir vs. high-dose amoxicillin/clavulanate oral suspension for acute otitis media in young children*

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Pages 1839-1847 | Accepted 24 Jul 2006, Published online: 16 Aug 2006

References

  • American Academy of Pediatrics and American Academy of Family Physicians. Subcommittee on Management of Acute Otitis Media. Clinical practice guideline: diagnosis and management of acute otitis media. Pediatrics 2004;113:1451–65
  • Antimicrobial agents and related therapy: principles of appropriate use for upper respiratory tract infections. In: Pickering LK, Baker CJ, McMillan J, et al., editors. Red Book: 2006 Report of the Committee on Infectious Diseases. 27th edn. Elk Grove Village, IL: American Academy of Pediatrics, 2006. pp.531–2
  • Pichichero ME, Casey JR. Acute otitis media: making sense of recent guidelines on antimicrobial treatment. J Fam Pract 2005;54:313–22
  • Center for Drug Evaluation and Research, U.S. Food and Drug Administration. Guidance for industry: acute otitis media – developing antimicrobial drugs for treatment, draft guidance. July 1998
  • Dowell SF, Butler JC, Giebink GS, et al. Acute otitis media: management and surveillance in an era of pneumococcal resistance – a report from the Drug-resistant Streptococcus pneumoniae Therapeutic Working Group. Pediatr Infect Dis J 1999;18:1–9
  • Pichichero ME, Reiner SA, Brook I, et al. Controversies in the medical management of persistent and recurrent acute otitis media. Recommendations of a clinical advisory committee. Ann Otol Rhinol Laryngol Suppl 2000;183:1–12
  • Omnicef® Prescribing Information. Abbott Laboratories ©2005. Available from http://www.abbott.com [Last accessed 16 May 2006]
  • Block SL, McCarty JM, Hedrick JA, et al. Comparative safety and efficacy of cefdinir vs amoxicillin/clavulanate for treatment of suppurative acute otitis media in children. Pediatr Infect Dis J 2000;19(Suppl):S159–65
  • Block SL, Busman TA, Paris MM, et al. Comparison of five-day cefdinir treatment with ten-day low dose amoxicillin/clavulanate treatment for acute otitis media. Pediatr Infect Dis J 2004;23:834–8
  • Block SL, Kratzer J, Nemeth MA, et al. Five-day cefdinir course vs. ten-day cefprozil course for treatment of acute otitis media. Pediatr Infect Dis J 2000;19(Suppl):S147–52
  • Block SL, Cifaldi M, Gu Y, et al. A comparison of 5 days of therapy with cefdinir or azithromycin in children with acute otitis media: a multicenter, prospective, single-blind study. Clin Ther 2005;27:786–94
  • Block SL, Hedrick J, Harrison CJ, et al. Community-wide vaccination with the heptavalent pneumococcal conjugate significantly alters the microbiology of acute otitis media. Pediatr Infect Dis J 2004;23:829–33
  • Eskola J, Kilpi T, Palmu A, et al. Efficacy of a pneumococcal conjugate vaccine against acute otitis media. N Engl J Med 2001;344:403–9
  • Casey JR, Pichichero ME. Changes in frequency and pathogens causing acute otitis media in 1995–2003. Pediatr Infect Dis J 2004;23:824–8
  • Iwai N. Drug compliance of children and infants with oral antibiotics for pediatric use. Acta Paediatr Jpn 1997;39: 132–42
  • Ramgoolam A, Steele R. Formulations of antibiotics for children in primary care: effects on compliance and efficacy. Paediatr Drugs 2002;4:323–33
  • Dagan R, Shvartzman P, Liss Z. Variation in acceptance of common oral antibiotic suspensions. Pediatr Infect Dis J 1994;13:686–90
  • Steele RW, Thomas MP, Begue RE. Compliance issues related to the selection of antibiotic suspensions for children. Pediatr Infect Dis J 2001;20:1–5
  • Block SL. Short-course antimicrobial therapy of streptococcal pharyngitis. Clin Pediatr 2003;42:663–71
  • Powers JL, Gooch WM 3rd, Oddo LP. Comparison of the palatability of the oral suspension of cefdinir vs. amoxicillin/ clavulanate potassium, cefprozil and azithromycin in pediatric patients. Pediatr Infect Dis J 2000;19(Suppl):S174–80
  • Wandstrat TL, Kaplan B. Pharmacoeconomic impact of factors affecting compliance with antibiotic regimens in the treatment of acute otitis media. Pediatr Infect Dis J 1997;16(Suppl):S27–9
  • D’Agostino RB, Massaro JM, Sullivan LM. Non-inferiority trials: design concepts and issues – the encounters of academic consultants in statistics. Statist Med 2003;22:169–86
  • Brittain E, Lin D. A comparison of intent-to-treat and per-protocol results in antibiotic inferiority studies. Statist Med 2005;24:1–10
  • Augmentin ES-600® Prescribing Information. GlaxoSmithKline ©2005. Available from http://www.gsk.com [Last accessed 16 May 2006]
  • Cifaldi MA, Paris MM, Devcich KJ, et al. Parent-reported outcomes for treatment of acute otitis media with cefdinir or amoxicillin/clavulanate oral suspensions. Paediatr Drugs 2004;6:387–93
  • Schmier JK, Cifaldi MA, Halpern MT. Validation of the otitis parent questionnaire (OPQ). International Society for Quality of Life Research Symposium; Boston, MA. June 27–29, 2004 [abstract 129]
  • Sanchez MM, Chen X. Choosing the analysis population in non-inferiority studies: per-protocol or intent-to-treat. Statist Med 2006;25:1169–81
  • Carlin SA, Marchant CD, Shurin PA, et al. Host factors and early therapeutic response in acute otitis media. J Pediatr 1991;118:178–83
  • Hoberman A, Paradise JL, Burch DJ, et al. Equivalent efficacy and reduced occurrence of diarrhea from a new formulation of amoxicillin/clavulanate potassium (Augmentin) for treatment of acute otitis media in children. Pediatr Infect Dis J 1997;16: 463–70
  • Cohen R, Levy C, Boucherat M, et al. Five vs. ten days of antibiotic therapy for acute otitis media in young children. Pediatric Infect Dis J 2000;19:458–63
  • Leibovitz E, Greenberg D, Piglansky L, et al. Recurrent acute otitis media occurring within one month from completion of antibiotic therapy: relationship to the original pathogen. Pediatr Infect Dis J 2003;22:209–16

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