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Original Article

Effect of growth hormone treatment on trunk fat accumulation in adult GH‐deficient Japanese patients:a randomised, placebo-controlled trial

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Pages 1973-1979 | Accepted 15 Aug 2006, Published online: 05 Sep 2006

References

  • Carroll PV, Christ ER, the Growth Hormone Research Society Scientific Committee. Growth hormone deficiency in adulthood and the effects of growth hormone replacement: a review. J Clin Endocrinol Metab 1998;83:382–95
  • Shalet SM, Toogood A, Rahim A, Brennan BM. The diagnosis of growth hormone deficiency in children and adults. Endocrine Rev 1998;19:203–23
  • Bengtsson B-A, Eden S, Lonn L, Kvist H, et al. Treatment of adults with growth hormone (GH) deficiency with recombinant human GH. J Clin Endocrinol Metab 1993;76:309–17
  • Larsson B, Svardsudd K, Welin L, Wilhemsen L, et al. Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: follow-up of participants in the study of men born in 1913. Br Med J 1984;288:1401–4
  • Empana JP, Ducimetiere P, Charles MA, Jouveon X. Sagittal abdominal diameter and risk of sudden death in asymptomatic middle-aged men: the Paris Prospective Study. Circulation 2004;110:2581–5
  • Tomlinson JW, Holden N, Hills RK, Wheatley K, et al. Association between premature mortality and hypopituitarism. Lancet 2001;357:425–31
  • Beshyah SA, Johnston DG. Cardiovascular disease and risk factors in adults with hypopituitarism. Clin Endocrinol 1999;50:1–15
  • Bülow B, Hagmar L, Mikoczy Z, Nordstöm CH, et al. Increased cerebrovascular mortality in patients with hypopituitarism. Clin Endocrinol 1997;46:75–81
  • Murakami Y, Yokoyama T, Oiso Y, Kato Y. Clinical features of adult hypopituitary patients in a national survey. In: Kato Y, editor. Annual report of the Japan Study Group on Hypothalamo-Pituitary Disorders. 2002. p. 170–6 [in Japanese]
  • Murakami Y, Kato Y. Hypercholesterolemia and obesity in adult patients with hypopituitarism: a report of a nation-wide survey in Japan. Endocr J 2003;50:759–65
  • Irie M, Itoh Y, Miyashita Y, Tsushima T, et al. Complications in adults with growth hormone deficiency – a survey study in Japan. Endocr J 2004;51:479–85
  • Ito H, Nakasuga K, Ohshima A, Maruyama T, et al. Detection of cardiovascular risk factors by indices of obesity obtained from anthropometry and dual-energy x-ray absorptiometry in Japanese individuals. Int J Obesity 2003;27:232–7
  • Growth Hormone Research Society. Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency: summary statement of the Growth Hormone Research Society workshop on adult growth hormone deficiency. J Clin Endocrinol Metab 1998;83:379–81
  • Shimatsu A, Fujieda K, Haniu K, Tanaka T, et al. Clinical study of measurements of IGF-I, IGF-II and IGFBP-3 using an IRMA kit. Report No 1. Study in adults. Horumon to Rinsho 1996;44:1129–38 [in Japanese]
  • Yoshiike N, Matsumura Y, Zaman MM, Yamaguchi M. Descriptive epidemiology of body mass index in Japanese adults in a representative sample from the National Nutrition Survey 1990–1994. Int J Obesity 1998;22:684–7
  • The Examination Committee of Criteria for ‘Obesity Disease’ in Japan, Japan Society for the Study of Obesity. New criteria for ‘obesity disease’ in Japan. Circulation J 2002;66:987–92
  • Chihara K, Koledova E, Shimatsu A, Kato Y, et al. Adult GH deficiency in Japanese patients: effects of GH treatment in a randomised, placebo-controlled trial. Eur J Endocrinol 2004;151:343–50
  • World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO Consultation on Obesity. WHO Geneva: WHO Technical Report Series No 894; 1998
  • Ito H, Ohshima A, Ohto N, Ogasawara M, et al. Relation between body composition and age in healthy Japanese subjects. Eur J Clin Nutr 2001;55:462–70
  • Irie M, Shizume K, Takano K, Kato Y, et al. Growth hormone replacement therapy in adults with growth hormone deficiency: a double-blind, placebo-controlled crossover trial in Japan. Endocrinol Metab 1995;2(Suppl B):17–23
  • Chihara K, Kato Y, Kohno H, Takano K, et al. Efficacy and safety of growth hormone (GH) in the treatment of adult Japanese patients with GH deficiency: a randomised, placebo-controlled study. Growth Horm IGF Res 2006;16:132–42
  • Attanasio AF, Lamberts SWJ, Matranga AMC, Birkett MA, et al. Adult growth hormone (GH)-deficient patients demonstrate heterogeneity between childhood onset and adult onset before and during human GH treatment. J Clin Endocrinol Metab 1997;82:82–8
  • Kehely A, Bates PC, Frewer P, Birkett M, et al. Short-term safety and efficacy of human GH replacement in 595 adults with GH deficiency: a comparison of two dosage algorithms. J Clin Endocrinol Metab 2002;87:1974–9

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