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Original Article

Effects of desloratadine and alcohol coadministration on psychomotor performance

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Pages 313-321 | Accepted 13 Dec 2006, Published online: 15 Jan 2007

References

  • Monroe EW. Chronic urticaria: review of non-sedating H1 antihistamines in treatment. J Am Acad Dermatol 1998;19(5 Pt 1):842–9
  • Simons FER. H1-receptor antagonists: safety issues. Ann Allergy Asthma Immunol 1999;83:481–8
  • Rosenzweig P, Patat A. Lack of behavioural toxicity of mizolastine: a review of the clinical pharmacology studies. Clin Exp Allergy 1999;29(Suppl 3):156–62
  • Simons FE. H1-receptor antagonists. Comparative tolerability and safety. Drug Saf 1994;10:350–80
  • Wilken JA, Berkowitz R, Kane R. Decrements in vigilance and cognitive functioning associated with ragweed-induced allergic rhinitis. Ann Allergy Asthma Immunol 2002;89:372–80
  • Verster JC, Volkerts ER. Antihistamines and driving ability: evidence from on-the-road driving studies during normal traffic. Ann Allergy Asthma Immunol 2004;92:294–304
  • Bradley CM, Nicholson AN. Studies on the central effects of the H1-antagonist, loratadine. Eur J Clin Pharmacol 1987;32:419–21
  • Nicholson AN, Stone BM, Turner C, et al. Antihistamines and aircrew: usefulness of fexofenadine. Aviat Space Environ Med 2000;71:2–6
  • Patat A, Stubbs D, Dunmore C, et al. Lack of interaction between two antihistamines, mizolastine and cetirizine, and ethanol in psychomotor and driving performance in healthy subjects. Eur J Clin Pharmacol 1995;48:143–50
  • Vermeeren A, O’Hanlon JF. Fexofenadine’s effects alone and with alcohol, on actual driving and psychomotor performance. J Allergy Clin Immunol 1998;101:306–11
  • Weiler JM, Bloomfield JR, Woodworth GG, et al. Effects of fexofenadine, diphenhydramine, and alcohol on driving performance: a randomized, placebo-controlled trial in the Iowa Driving Simulator. Ann Intern Med 2000;132:354–63
  • Vermeeren A. Ramaekers JG, O’Hanlon JF. Effects of emedastine and cetirizine, alone and with alcohol, on actual driving of males and females. J Psychopharmacol 2002;16:57–64
  • Ridout F, Shamsi Z, Meadows R, et al. A single-center, randomized, double-blind, placebo-controlled, crossover investigation of the effects of fexofenadine hydrochloride 180 mg alone and with alcohol, with hydroxyzine hydrochloride 50 mg as a positive internal control, on aspects of cognitive and psychomotor function related to driving a car. Clin Ther 2003;25:1518–38
  • Kreutner W, Hey JA, Chiu P, et al. Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication: lack of central nervous system and cardiovascular effects. Arzneimittelforschung 2000;50: 345–52
  • Berger WE. The safety and efficacy of desloratadine for the management of allergic disease. Drug Saf 2005;28:1101–18
  • Cayen M, Wang E, Clement RP, et al. Effect of desloratadine on p-glycoprotein transport system (MDR1). Allergy 2000;55\(Suppl 63):282. Abstract 1009
  • Geha RS, Meltzer EO. Desloratadine: a new, nonsedating, oral antihistamine. J Allergy Clin Immunol 2001;107:751–62
  • Wang E-J, Casciano CN, Clement RP, et al. Evaluation of the interaction of loratadine and desloratadine with P-glycoprotein. Drug Metab Disp 2001;29:1080–3
  • Nicholson AN, Handford AD, Turner C, et al. Studies on performance and sleepiness with the H1-antihistamine, desloratadine. Aviat Space Environ Med 2003;74:809–15
  • Wilken JA, Kane RL, Ellis AK, et al. A comparison of the effect of diphenhydramine and desloratadine on vigilance and cognitive function during treatment of ragweed-induced allergic rhinitis. Ann Allergy Asthma Immunol 2003;91:375–85
  • Scharf MB, Kay GC, Rikken G, et al. Desloratadine has no effect on wakefulness or psychomotor performance. Allergy 2000;55\(Suppl 63):280. Abstract 1001
  • Valk PJ, Van Roon DB, Simons RM, et al. Desloratadine shows no effect on performance during 6 h at 8,000 ft simulated cabin altitude. Aviat Space Environ Med 2004;75:433–8
  • Vuurman EFPM, Rikken GH, Muntjewerff ND, et al. Effects of desloratadine, diphenhydramine, and placebo on driving performance and psychomotor performance measurements. Eur J Clin Pharmacol 2004;60:307–13
  • Clarinex [prescribing information]. Kenilworth, NJ; Schering Corporation; 2005
  • Widmark EMP. Principles and Applications of Medicolegal Alcohol Determination. Foster City, Calif: Biomedical Publications, 1981
  • Kasnis A, Gokula RM. Romberg’s test. J Postgrad Med 2003;49:169–72
  • Hoddes E, Zarcone V, Smythe H, et al. Quantification of sleepiness: a new approach. Psychophysiology 1973;10:431–6
  • Joy S, Fein D, Kaplan E. Decoding digit symbol: speed, memory and visual scanning. Assessment. 2003;10:56–65
  • Kane RL, Kay GG. Computerized assessment in neuropsychology: a review of tests and test batteries. Neuropsychol Rev 1992;3:1–117
  • Graw P, Werth E, Krauchi K, et al. Early morning melatonin administration impairs psychomotor vigilance. Behav Brain Res 2001;121:167–72
  • Notermans NC, van Dijk GW, van der Graaf Y, et al. Measuring ataxia: quantification based on the standard neurological examination. J Neurol Neurosurg Psychiatry 1994;57:22–6
  • Meltzer EO. Comparative study of H1 antihistamines. Ann Allergy 1991;67:625–33
  • Meltzer EO. Performance effects of antihistamines. J Allergy Clin Immunol 1990;86:613–19
  • Simons FE, Simons KJ. Second-generation H1-receptor antagonists. Ann Allergy 1991;66: 5–16,19
  • Burns M, Moskowitz H. Effects of diphenhydramine and alcohol on skills performance. Eur J Clin Pharmacol 1980;17:259–66
  • Baugh R, Calvert RT. The effect of diphenhydramine alone and in combination with ethanol on histamine skin response and mental performance. Eur J Clin Pharmacol 1997;12:201–4
  • Ramaekers JG, Uiterwijk MM, O’Hanlon JF. Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during driving. Eur J Clin Pharmacol 1992;42:363–9

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