References
- Xyzal [package insert]. Bridgewater, NJ, and Smyrna, GA: sanofi-aventis U.S. LLC, and UCB, Inc., 2009
- Gillard M, Christophe B, Wels B, et al. H1 antagonists: receptor affinity versus selectivity. Inflamm Res 2003;52(Suppl. 1):S49-50
- Grant JA, Riethuisen JM, Moulaert B, et al. A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects. Ann Allergy Asthma Immunol 2002;88:190-7
- Bachert C, Bousquet J, Canonica GW, et al. Levocetirizine improves quality of life and reduces costs in long-term management of persistent allergic rhinitis. J Allergy Clin Immunol 2004;114:838-44
- Segall N, Gawchik SM, Georges G, et al. Efficacy and safety of levocetirizine in improving symptoms and health-related quality of life in US adults with seasonal allergic rhinitis: a randomized, placebo-controlled study. Ann Allergy Asthma Immunol 2010;104:259–267
- Juniper EF, Guyatt GH. Development and testing of a new measure of health status for clinical trials in rhinoconjunctivitis. Clin Exp Allergy 1991;21:77-83
- Juniper EF, Guyatt GH, Griffith LE, et al. Interpretation of rhinoconjunctivitis quality of life questionnaire data. J Allergy Clin Immunol 1996;98:843-5
- Reilly M, Zbrozek AS, Dukes EM. The validity and reproducibility of a work productivity and activity impairment instrument. Pharmacoeconomics 1992;4:353-65
- Reilly MC, Tanner A, Meltzer EO. Work, classroom and activity impairment instruments: validation studies in allergic rhinitis. Clin Drug Investig 1996;11:278-88
- Johns MW. A new method for measuring daytime sleepiness: the Epworth Sleepiness Scale. Sleep 1991;14:540-5
- Johns MW. Reliability and factor analysis of the Epworth Sleepiness Scale. Sleep 1992;15:376-81
- Gawchik SM, Segall N, Georges G, et al. Randomized, placebo-controlled multicenter trial evaluating the effects of levocetirizine on symptoms, work productivity and daytime sleepiness in US adults with seasonal allergic rhinitis [abstract]. Presented at: Western Society of Allergy, Asthma and Immunology (WSAAI), Maui, HI, January 25–29, 2009
- Segall N, Gawchik SM, Georges G, et al. The efficacy, safety, and impact on health-related quality of life (HRQoL) of levocetirizine in US adults with seasonal allergic rhinitis [abstract]. Presented at: Southwest Allergy Forum (SWAF), Puerto Vallarta, Mexico, January 14–18, 2009
- Temple R, Ellenberg SS. Placebo-controlled trials and active-control trials in the evaluation of new treatments. Part 1: ethical and scientific issues. Ann Intern Med 2000;133:455-63