309
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Acute bacterial otitis externa: efficacy and safety of topical treatment with an antibiotic ear drop formulation in comparison to glycerol treatment

, , &
Pages 871-878 | Accepted 21 Jan 2011, Published online: 05 Apr 2011

References

  • Hannley MT, Denneny JC 3rd, Holzer SS. Use of ototopical antibiotics in treating 3 common ear diseases. Otolaryngol Head Neck Surg 2000;122:934-40
  • Roland PS, Stroman DW. Microbiology of acute otitis externa. Laryngoscope 2002;112:1166-77
  • Robertson DG, Bennett JD. The general practice 'management of otitis externa'. J R Army Med Corps 1992;138:27-32
  • van Balen FA. Clinical efficacy of three common treatments in acute otitis externa in primary care: randomised controlled trial. BMJ 2003;327:1201-5
  • Singer DE. Otitis externa; bacteriological and mycological studies. Ann Otol Rhinol Laryngol 1952;61:317-30
  • Cassisi N. Diffuse otitis externa: clinical and microbiologic findings in the course of a multicenter study on a new otic solution. Ann Otol Rhinol Laryngol Suppl 1977;86:1-16
  • Beers SL, Abramo TJ. Otitis externa review. Pediatr Emerg Care 2004;20:250-6
  • Battikhi MN, Ammar SI. Otitis externa infection in Jordan. Clinical and microbiological features. Saudi Med J 2004;25:1199-203
  • Agius AM, Pickles JM, Burch KL. A prospective study of otitis externa. Clin Otolaryngol Allied Sci 1992;17:150-4
  • Hoadley AW, Knight DE. External otitis among swimmers and nonswimmers. Arch Environ Health 1975;30:445-8
  • Senturia BH, Carr CD. Studies of factors considered responsible for diseases of the external ear. I. Survival of exogenous bacteria in the external auditory canal under varied conditions. Laryngoscope 1958;68:2052-79
  • Shea CR. Dermatologic diseases of the external auditory canal. Otolaryngol Clin North Am 1996;29:783-94
  • Daneshrad D, Kim JC, Amedee RG. Acute otitis externa. J La State Med Soc 2002;154:226-8
  • Hughes E, Lee JH. Otitis externa. Pediatr Rev 2001;22:191-7
  • Russell JD. What causes acute otitis externa? J Laryngol Otol 1993;107:898-901
  • Springer GL, Shapiro ED. Fresh water swimming as a risk factor for otitis externa: a case–control study. Arch Environ Health 1985;40:202-6
  • Hirsch BE. Infections of the external ear. Am J Otolaryngol 1992;13:145-55
  • Gray RF, Sharma A, Vowler SL. Relative humidity of the external auditory canal in normal and abnormal ears, and its pathogenic effect. Clin Otolaryngol 2005;30:105-11
  • Nussinovitch M. Cotton-tip applicators as a leading cause of otitis externa. Int J Pediatr Otorhinolaryngol 2004; 68:433-5
  • Naumann A. Chronisch rezidivierende Otitis externa – Übertriebene Ohrhygiene kann sich rächen. MMW – Fortschr Med 2003;145:864-7
  • Roland PS, Parry DA, Stroman DW. Microbiology of acute otitis media with tympanostomy tubes. Otolaryngol Head Neck Surg 2005;133:585-95
  • Clark WB. Microbiology of otitis externa. Otolaryngol Head Neck Surg 1997;116:23-5
  • Dibb WL. The normal microbial flora of the outer ear canal in healthy Norwegian individuals. NIPH Ann 1990;13:11-16
  • Brook I, Frazier EH, Thompson DH. Aerobic and anaerobic microbiology of external otitis. Clin Infect Dis 1992;15:955-8
  • Torum B. Efficacy of ofloxacin otic solution once daily for 7 days in the treatment of otitis externa: a multicenter, open-label, phase III trial. Clin Ther 2004;26:1046-54
  • Conroy PJ. New quinolone/steroid combination for topical treatment of acute otitis: early- and late-phase study results. Ear Nose Throat J 2003;82:2-4
  • Eady EA, Cove JH. Topical antibiotic therapy: current status and future prospects. Drugs Exp Clin Res 1990;16:423-33
  • Michel O. Infektionen des äußeren Ohrs – Therapie total oder lokal? HNO-Nachrichten 2003;6:30-3
  • Ganz H. Bakterielle Otitis externa mit Überschreitung der Organgrenzen – systemische und lokale Kombinationsbehandlung mit Ciprofloxacin. Z Ärztl Fortbild 1993;87:413–15
  • Rutka J. Acute otitis externa: treatment perspectives. Ear Nose Throat J 2004;83:20-1; discussion 21-2
  • Diagnosis and treatment of acute otitis externa. An interdisciplinary update. Ann Otol Rhinol Laryngol Suppl 1999;176:1-23
  • Emgard P, Hellstrom S. A group III steroid solution without antibiotic components: an effective cure for external otitis. J Laryngol Otol 2005;119:342-7
  • Ruth M. A clinical comparison of hydrocortisone butyrate with oxytetracycline/hydrocortisone acetate-polymyxin B in the local treatment of acute external otitis. Eur Arch Otorhinolaryngol 1990;247:77-80
  • Senturia BH, Alford V. Hydrocortisone acetate and neomycin in otic infections. Laryngoscope 1954;64:834-44
  • Feiwel M, Munro-Ashman D. Hypersensitivity to Neomycin. Br Med J 1965;1:994-5
  • Sood S. Allergic otitis externa. Clin Otolaryngol Allied Sci 2002;27:233-6
  • Arnes E, Dibb WL. Otitis externa: clinical comparison of local ciprofloxacin versus local oxytetracycline, polymyxin B, hydrocortiosone combination treatment. Curr Med Res Opin 1993;13:182-6
  • Drehobl M, Guerrero JL, Lacarte PR, et al. Comparison of efficacy and safety of ciprofloxacin otic solution 0.2% versus polymyxin B–neomycin–hydrocortisone in the treatment of acute diffuse otitis externa. Curr Med Res Opin 2008;24:3531-2
  • Goldenberg D, Golz A, Netzer A, et al. The use of otic powder in the treatment of acute external otitis. Am J Otolaryngol 2002;23:142-7
  • Jones RN, Milazzo J, Seidlin M. Ofloxacin otic solution for treatment of otitis externa in children and adults. Arch Otolaryngol Head Neck Surg 1997;23:1193-200
  • Pistorius B, Westberry K, Drehobl M, et al. Prospective, randomized, comparative trial of ciprofloxacin otic drops, with or without hydrocortisone, vs. polymyxin B–neomycinhydrocortisone otic suspension in the treatment of acute diffuse otitis externa. Infect Dis Clin Pract 1999;8:387-95
  • Schwartz RH. Once-daily ofloxacin otic solution versus neomycin sulfate/polymyxin B sulfate/hydrocortisone otic suspension four times a day: a multicenter, randomized, evaluator-blinded trial to compare the efficacy, safety, and pain relief in pediatric patients with otitis externa. Curr Med Res Opin 2006;22:1725-36
  • Leyden JJ, Kligman AM. Contact dermatitis to neomycin sulfate. JAMA 1979;242:1276-8
  • Rakover Y, Keywan K, Rosen G. Safety of topical ear drops containing ototoxic antibiotics. J Otolaryngol 1997;26:194-6

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.