Insulin initiation in elderly patients with type 2 diabetes in France: a subpopulation of the LIGHT study

References

• Bonaldi C, Romon I, Fagot-Campagna A. Impacts du vieillissement de la population et de l’obésité sur l’évolution de la prévalence du diabète traité: situation de la France métropolitaine à l’horizon 2016. Bulletin Epidemiologique Hebdomadaire 2006;10:69-76
   Google Scholar
• Fagot-Campagna A, Bourdel-Marchasson I, Simon D. Burden of diabetes in an aging population: prevalence, incidence, mortality, characteristics and quality of care. Diabetes Metab 2005;31:5S35-5S52
   PubMed Web of Science ®Google Scholar
• Fagot-Campagna A, Fosse S, Roudier C, et al, pour le Comité scientifique d’Entred. Characteristics, vascular risk and complications in people with diabetes, in metropolitan France: major improvements between ENTRED 2001 and ENTRED 2007 studies. Bulletin Epidemiologique Hebdomadaire 2009;42-43:455-60
   Google Scholar
• Bertoni AG, Krop JS, Anderson GF, et al. Diabetes-related morbidity and mortality in a national sample of U.S. elders. Diabetes Care 2002;25:471-5
   PubMed Web of Science ®Google Scholar
• Samos LF, Roos BA. Diabetes mellitus in older persons. Med Clin North Am 1998;82:791-803
   PubMed Web of Science ®Google Scholar
• Meneilly GS, Cheung E, Tuokko H. Counterregulatory hormone responses to hypoglycemia in the elderly patient with diabetes. Diabetes 1994;43:403-10
   PubMed Web of Science ®Google Scholar
• Lassmann-Vague V. Hypoglycaemia in elderly diabetic patients. Diabetes Metab 2005;31:5S53-5S57
   PubMedGoogle Scholar
• Lindström T, Jorfeldt L, Tegler L, et al. Hypoglycaemia and cardiac arrhythmias in patients with type 2 diabetes mellitus. Diabet Med 1992;9:536-41
   PubMed Web of Science ®Google Scholar
• Desouza C, Salazar H, Cheong B, et al. Association of hypoglycaemia and cardiac ischaemia: a study based on continuous monitoring. Diabetes Care 2003;26:1485-9
   PubMed Web of Science ®Google Scholar
• Whitmer RA, Karter AJ, Yaffe K, et al. Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus. JAMA 2009;301:1565-72
   PubMed Web of Science ®Google Scholar
• Duckworth W, Abraira C, Moritz T, et al. VADT Investigators. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 2009;360:129-39
   PubMed Web of Science ®Google Scholar
• ACCORD Study Group, Gerstein HC, Miller ME, et al. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 2008;358:2545-59
   PubMed Web of Science ®Google Scholar
• Lachin JM. Point: intensive glycemic control and mortality in ACCORD – a chance finding? Diabetes Care 2010;33:2719-21
   PubMed Web of Science ®Google Scholar
• Riddle, MC. Counterpoint: intensive glucose control and mortality in ACCORD – still looking for clues. Diabetes Care 2010;33:2722-4
   PubMed Web of Science ®Google Scholar
• Schwartz AV, Vittinghoff E, Sellmeyer DE, et al. Health, Aging, and Body Composition Study. Diabetes-related complications, glycemic control, and falls in older adults. Diabetes Care 2008;31:391-6
   PubMed Web of Science ®Google Scholar
• Ober SK, Watts S, Lawrence RH. Insulin use in elderly diabetic patients. Clin Interv Aging 2006;1:107-13
   PubMed Web of Science ®Google Scholar
• Constans T. Plasma glucose goals and therapeutic management in elderly diabetic patients. Diabetes Metab 2005;31:5S58-5S61
   PubMed Web of Science ®Google Scholar
• Pornet C, Bourdel-Marchasson I, Lecomte P, et al., for the ENTRED Scientific Committee. Trends in the quality of care for elderly people with type 2 diabetes: the need for improvements in safety and quality (the 2001 and 2007 ENTRED Surveys). Diabetes Metab 2011;37:152-61
   PubMedGoogle Scholar
• Blicklé JF, Attali JR, Barrou Z, et al. Rapport des experts de l’ALFEDIAM. Le diabète du sujet âgé. Diabetes Metab 1999;25:84-93
   PubMedGoogle Scholar
• Sweileh WM. Contraindications to metformin therapy among patients with type 2 diabetes mellitus. Pharm World Sci 2007;29:587-92. Erratum in Pharm World Sci 2007;29:573
   PubMed Web of Science ®Google Scholar
• Nathan DM, Buse JB, Davidson MB, et al. American Diabetes Association; European Association for Study of Diabetes. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009;32:193-203
   PubMed Web of Science ®Google Scholar
• Doucet J. Use of antidiabetic drugs in elderly patients. Diabetes Metab 2005;31:5S98-5S104
   PubMed Web of Science ®Google Scholar
• Heinemann L, Linkeschova R, Rave K, et al. Time–action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo. Diabetes Care 2000;23:644-9
   PubMed Web of Science ®Google Scholar
• Lepore M, Pampanelli S, Fanelli C, et al. Pharmacokinetics and pharmacodynamics of subcutaneous injection of long-acting human insulin analog glargine, NPH insulin, and ultralente human insulin and continuous subcutaneous infusion of insulin lispro. Diabetes 2000;49:2142-8
   PubMed Web of Science ®Google Scholar
• Hovath K, Jeitler K, Berghold A, et al. Long-acting analogues versus NPH insulin (human isophane insulin) for type 2 diabetes mellitus. Cochrane Database Syst Rev 2007;CD005613
   Google Scholar
• Bazzano LA, Lee LJ, Reynolds K, et al. Safety and efficacy of glargine compared with NPH insulin for the treatment of Type 2 diabetes: a meta-analysis of randomized controlled trials. Diabet Metab 2008;25:924-32
   PubMed Web of Science ®Google Scholar
• Philis-Tsimikas A, Charpentier G, Clauson P, et al. Comparison of once-daily insulin detemir with NPH insulin added to a regimen of oral antidiabetic drugs in poorly controlled type 2 diabetes. Clin Ther 2006;28:1569-81
   PubMed Web of Science ®Google Scholar
• Garber AJ, Clauson P, Pedersen CB, et al. Lower risk of hypoglycaemia with insulin detemir than with neutral protamine hagedorn insulin in older persons with type 2 diabetes: a pooled analysis of phase III trials. J Am Geriatr Soc 2007;55:1735-40
   PubMed Web of Science ®Google Scholar
• Brez S, Rowan M, Malcolm J, et al. Transition from specialist to primary diabetes care: a qualitative study of perspectives of primary care physicians. BMC Fam Pract 2009;10:39
   PubMedGoogle Scholar
• Vergès B, Brun JM, Tawil C, et al. Strategies for insulin initiation: insights from the French LIGHT observational study. Diabetes Metab Res Rev. 2012 Jan;28(1):97-105
   Google Scholar
• ALFEDIAM. Guide pour la prise en charge du diabétique âgé. 1ère édition. Medecine des Maladies Metaboliques 2008;2:1-120
   Google Scholar
• Doucet B, Bauduceau J-P, Le Floch JP, et al. Étude GERODIAB: descriptif de 985 patients diabétiques de type 2 âgés de plus de 70 ans. Diabetes Metab 2011;37(Suppl 1):A59
   PubMedGoogle Scholar
• Yki-Järvinen H. Combination therapies with insulin in type 2 diabetes. Diabetes Care 2001;24:758-67
   PubMed Web of Science ®Google Scholar
• Yki-Järvinen H, Ryysy L, Kaupilla M, et al. Effect of obesity on the response to insulin therapy in non-insulin dependent diabetes mellitus. J Clin Endocrinol Metab 1997;82:4037-43
   PubMed Web of Science ®Google Scholar
• Korytkowski M. When oral agents fail: practical barriers to starting insulin. Int J Obes Relat Metab Disord 2002;26(Suppl 3):S18-S24
   PubMed Web of Science ®Google Scholar
• Russell-Jones D, Khan R. Insulin-associated weight gain in diabetes – causes, effects and coping mechanisms. Diabetes Obes Metab 2007;9:799-812
   PubMed Web of Science ®Google Scholar
• Donnelly LA, Morris AD, Evans JM; DARTS/MEMO collaboration. Adherence to insulin and its association with glycaemic control in patients with type 2 diabetes. QJM 2007;100:345-50
   PubMed Web of Science ®Google Scholar
• Brownie S. Why are elderly individuals at risk of nutritional deficiency? Int J Nurs Pract 2006;12:110-18
   PubMedGoogle Scholar
• Ligthelm RJ, Borzì V, Gumprecht J, et al. Importance of observational studies in clinical practice. Clin Ther 2007;29:1284-92
   Web of Science ®Google Scholar