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Osteoporosis: Letter to the Editor

Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial

Pages 609-610 | Published online: 21 Mar 2012

References

  • Tat SK, Pelletier JP, Mineau F, et al. Strontium ranelate inhibits key factors affecting bone remodelling in human osteoarthritic subchondral bone osteoblasts. Bone 2011;49:559-67
  • Reginster JY, Bruyere O, Collette J. Strontium ranelate treatment increases osteoprotegerin serum levels in postmenopausal osteoporotic women. Bone Jan 12. Epub ahead of print. doi:10.1016/j.bone.2011.12.024
  • Gulhan I, Bilgili S, Gunaydin R, et al. The effect of strontium ranelate on serum insulin like growth factor-1 and leptin levels in osteoporotic post-menopausal women: a prospective study. Arch Gynecol Obstet 2008;278:437-41
  • Montaseri A, Busch F. Mobasheri A, et al. IGF-1 and PDGF-bb suppress IL1-β-induced cartilage degradation though down-regulation of NFκB signalling: involvement of Src/PI-3K/AKT pathway. PloS One 2011;6(12)e28663.doi:10.1371/journal.pone.0028663
  • Henrotin Y, Labasse A, Zheng SX, et al. Strontium ranelate increases cartilage matrix formation. J Bone Miner Res 2001;16:299-308

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