Spondylodiscitis: standards of current treatment

References

• Guerado E, Cervan AM. Surgical treatment of spondylodiscitis. An update. Int Orthop 2012;36:413-20
   PubMed Web of Science ®Google Scholar
• Reihsaus E, Waldbaur H, Seeling W. Spinal epidural abscess: a meta-analysis of 915 patients. Neurosurg Rev 2000;23:175-204; discussion 205
   PubMed Web of Science ®Google Scholar
• Soehle M, Wallenfang T. Spinal epidural abscesses: clinical manifestations, prognostic factors, and outcomes. Neurosurgery 2002;51:79-85; discussion 86-7
   PubMed Web of Science ®Google Scholar
• Morelli S, Carmenini E, Caporossi AP, et al. Spondylodiscitis and infective endocarditis: case studies and review of the literature. Spine (Phila Pa 1976) 2001;26:499-500
   PubMed Web of Science ®Google Scholar
• Torda AJ, Gottlieb T, Bradbury R. Pyogenic vertebral osteomyelitis: analysis of 20 cases and review. Clin Infect Dis 1995;20:320-8
   PubMed Web of Science ®Google Scholar
• Lafont A, Olive A, Gelman M, et al. Candida albicans spondylodiscitis and vertebral osteomyelitis in patients with intravenous heroin drug addiction. Report of 3 new cases. J Rheumatol 1994;21:953-6
   PubMed Web of Science ®Google Scholar
• D'Agostino C, Scorzolini L, Massetti AP, et al. A seven-year prospective study on spondylodiscitis: epidemiological and microbiological features. Infection 2010;38:102-7
   PubMed Web of Science ®Google Scholar
• Maiuri F, Iaconetta G, Gallicchio B, et al. Spondylodiscitis. Clinical and magnetic resonance diagnosis. Spine (Phila Pa 1976) 1997;22:1741-6
   PubMed Web of Science ®Google Scholar
• Colmenero JD, Jimenez-Mejias ME, Sanchez-Lora FJ, et al. Pyogenic, tuberculous, and brucellar vertebral osteomyelitis: a descriptive and comparative study of 219 cases. Ann Rheum Dis 1997;56:709-15
   PubMed Web of Science ®Google Scholar
• Mylona E, Samarkos M, Kakalou E, et al. Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics. Semin Arthritis Rheum 2009;39:10-17
   PubMed Web of Science ®Google Scholar
• Kowalski TJ, Berbari EF, Huddleston PM, et al. The management and outcome of spinal implant infections: contemporary retrospective cohort study. Clin Infect Dis 2007;44:913-20
   PubMed Web of Science ®Google Scholar
• Bucher E, Trampuz A, Donati L, et al. Spondylodiscitis associated with bacteraemia due to coagulase-negative staphylococci. Eur J Clin Microbiol Infect Dis 2000;19:118-20
   PubMed Web of Science ®Google Scholar
• McHenry MC, Easley KA, Locker GA. Vertebral osteomyelitis: long-term outcome for 253 patients from 7 Cleveland-area hospitals. Clin Infect Dis 2002;34:1342-50
   PubMed Web of Science ®Google Scholar
• Priest DH, Peacock JE Jr. Hematogenous vertebral osteomyelitis due to Staphylococcus aureus in the adult: clinical features and therapeutic outcomes. South Med J 2005;98:854-62
   PubMed Web of Science ®Google Scholar
• Stoeckle M, Kaech C, Trampuz A, et al. The role of diabetes mellitus in patients with bloodstream infections. Swiss Med Wkly 2008;138:512-19
   PubMed Web of Science ®Google Scholar
• Sobottke R, Zarghooni K, Krengel M, et al. Treatment of spondylodiscitis in human immunodeficiency virus-infected patients: a comparison of conservative and operative therapy. Spine (Phila Pa 1976) 2009;34:E452-8
   PubMedGoogle Scholar
• Geyik MF, Gur A, Nas K, et al. Musculoskeletal involvement of brucellosis in different age groups: a study of 195 cases. Swiss Med Wkly 2002;132:98-105
   PubMed Web of Science ®Google Scholar
• Raptopoulou A, Karantanas AH, Poumboulidis K, et al. Brucellar spondylodiscitis: noncontiguous multifocal involvement of the cervical, thoracic, and lumbar spine. Clin Imaging 2006;30:214-17
   PubMed Web of Science ®Google Scholar
• Guzey FK, Emel E, Sel B, et al. Cervical spinal brucellosis causing epidural and prevertebral abscesses and spinal cord compression: a case report. Spine J 2007;7:240-4
   PubMed Web of Science ®Google Scholar
• Beronius M, Bergman B, Andersson R. Vertebral osteomyelitis in Goteborg, Sweden: a retrospective study of patients during 1990–95. Scand J Infect Dis 2001;33:527-32
   PubMed Web of Science ®Google Scholar
• Tuli SM. Severe kyphotic deformity in tuberculosis of the spine. Int Orthop 1995;19:327-31
   PubMed Web of Science ®Google Scholar
• Bloch AB, Cauthen GM, Onorato IM, et al. Nationwide survey of drug-resistant tuberculosis in the United States. JAMA 1994;271:665-71
   PubMed Web of Science ®Google Scholar
• Pirofsky JG, Huang CT, Waites KB. Spinal osteomyelitis due to Mycobacterium avium-intracellulare in an elderly man with steroid-induced osteoporosis. Spine (Phila Pa 1976) 1993;18:1926-9
   PubMed Web of Science ®Google Scholar
• Robson JM, Harte GJ, Osborne DR, et al. Cat-scratch disease with paravertebral mass and osteomyelitis. Clin Infect Dis 1999;28:274-8
   PubMed Web of Science ®Google Scholar
• Hadjipavlou AG, Mader JT, Necessary JT, et al. Hematogenous pyogenic spinal infections and their surgical management. Spine (Phila Pa 1976) 2000;25:1668-79
   PubMed Web of Science ®Google Scholar
• Meyer B, Schaller K, Rohde V, et al. The C-reactive protein for detection of early infections after lumbar microdiscectomy. Acta Neurochir (Wien) 1995;136:145-50
   PubMed Web of Science ®Google Scholar
• Rohde V, Meyer B, Schaller C, et al. Spondylodiscitis after lumbar discectomy. Incidence and a proposal for prophylaxis. Spine (Phila Pa 1976) 1998;23:615-20
   PubMed Web of Science ®Google Scholar
• Mok JM, Pekmezci M, Piper SL, et al. Use of C-reactive protein after spinal surgery: comparison with erythrocyte sedimentation rate as predictor of early postoperative infectious complications. Spine (Phila Pa 1976) 2008;33:415-21
   PubMed Web of Science ®Google Scholar
• Takahashi J, Ebara S, Kamimura M, et al. Early-phase enhanced inflammatory reaction after spinal instrumentation surgery. Spine (Phila Pa 1976) 2001;26:1698-704
   PubMed Web of Science ®Google Scholar
• Patzakis MJ, Rao S, Wilkins J, et al. Analysis of 61 cases of vertebral osteomyelitis. Clin Orthop Relat Res 1991;264:178-83
   PubMed Web of Science ®Google Scholar
• Rezai AR, Lee M, Cooper PR, et al. Modern management of spinal tuberculosis. Neurosurgery 1995;36:87-97; discussion 97-8
   PubMed Web of Science ®Google Scholar
• Kaul KL. Molecular detection of Mycobacterium tuberculosis: impact on patient care. Clin Chem 2001;47:1553-8
   PubMed Web of Science ®Google Scholar
• La Scola B, Michel G, Raoult D. Use of amplification and sequencing of the 16S rRNA gene to diagnose Mycoplasma pneumoniae osteomyelitis in a patient with hypogammaglobulinemia. Clin Infect Dis 1997;24:1161-3
   PubMed Web of Science ®Google Scholar
• Weigl JA, Haas WH. Postoperative Mycobacterium avium osteomyelitis confirmed by polymerase chain reaction. Eur J Pediatr 2000;159:64-9
   PubMed Web of Science ®Google Scholar
• Martin RJ, Yuan HA. Neurosurgical care of spinal epidural, subdural, and intramedullary abscesses and arachnoiditis. Orthop Clin North Am 1996;27:125-36
   PubMed Web of Science ®Google Scholar
• Darouiche RO, Hamill RJ, Greenberg SB, et al. Bacterial spinal epidural abscess. Review of 43 cases and literature survey. Medicine (Baltimore) 1992;71:369-85
   PubMed Web of Science ®Google Scholar
• Palestro CJ, Love C, Miller TT. Infection and musculoskeletal conditions: imaging of musculoskeletal infections. Best Pract Res Clin Rheumatol 2006;20:1197-218
   PubMed Web of Science ®Google Scholar
• Kopecky KK, Gilmor RL, Scott JA, et al. Pitfalls of computed tomography in diagnosis of discitis. Neuroradiology 1985;27:57-66
   PubMed Web of Science ®Google Scholar
• Champsaur P, Parlier-Cuau C, Juhan V, et al. [Differential diagnosis of infective spondylodiscitis and erosive degenerative disk disease]. J Radiol 2000;81:516-22
   PubMedGoogle Scholar
• Raininko RK, Aho AJ, Laine MO. Computed tomography in spondylitis. CT versus other radiographic methods. Acta Orthop Scand 1985;56:372-7
   PubMed Web of Science ®Google Scholar
• An HS, Masuda K, Inoue N. Intervertebral disc degeneration: biological and biomechanical factors. J Orthop Sci 2006;11:541-52
   PubMed Web of Science ®Google Scholar
• Razak M, Kamari ZH, Roohi S. Spinal infection – an overview and the results of treatment. Med J Malaysia 2000;55(Suppl C):18-28
   PubMedGoogle Scholar
• Arya S, Crow WN, Hadjipaviou AG, et al. Percutaneous transpedicular management of discitis. J Vasc Interv Radiol 1996;7:921-7
   PubMed Web of Science ®Google Scholar
• Muckley T, Schutz T, Kirschner M, et al. Psoas abscess: the spine as a primary source of infection. Spine (Phila Pa 1976) 2003;28:E106-13
   PubMed Web of Science ®Google Scholar
• Love C, Patel M, Lonner BS, et al. Diagnosing spinal osteomyelitis: a comparison of bone and Ga-67 scintigraphy and magnetic resonance imaging. Clin Nucl Med 2000;25:963-77
   PubMed Web of Science ®Google Scholar
• An HS, Seldomridge JA. Spinal infections: diagnostic tests and imaging studies. Clin Orthop Relat Res 2006;444:27-33
   PubMed Web of Science ®Google Scholar
• Modic MT, Feiglin DH, Piraino DW, et al. Vertebral osteomyelitis: assessment using MR. Radiology 1985;157:157-66
   PubMed Web of Science ®Google Scholar
• Hadjipavlou AG, Cesani-Vazquez F, Villaneuva-Meyer J, et al. The effectiveness of gallium citrate Ga 67 radionuclide imaging in vertebral osteomyelitis revisited. Am J Orthop (Belle Mead NJ) 1998;27:179-83
   PubMedGoogle Scholar
• Strobel K, Stumpe KD. PET/CT in musculoskeletal infection. Semin Musculoskelet Radiol 2007;11:353-64
   PubMed Web of Science ®Google Scholar
• Vanninen E, Laitinen T, Partanen K, et al. Late correlative imaging findings of previous acute infective spondylitis. Clin Nucl Med 2000;25:779-84
   PubMed Web of Science ®Google Scholar
• Gasbarrini A, Boriani L, Nanni C, et al. Spinal infection multidisciplinary management project (SIMP): from diagnosis to treatment guideline. Int J Immunopathol Pharmacol 2011;24(1 Suppl 2):95-100
   PubMed Web of Science ®Google Scholar
• Termaat MF, Raijmakers PG, Scholten HJ, et al. The accuracy of diagnostic imaging for the assessment of chronic osteomyelitis: a systematic review and meta-analysis. J Bone Joint Surg Am 2005;87:2464-71
   PubMed Web of Science ®Google Scholar
• de Winter F, van de Wiele C, Vogelaers D, et al. Fluorine-18 fluorodeoxyglucose-position emission tomography: a highly accurate imaging modality for the diagnosis of chronic musculoskeletal infections. J Bone Joint Surg Am 2001;83:651-60
   PubMed Web of Science ®Google Scholar
• Schiesser M, Stumpe KD, Trentz O, et al. Detection of metallic implant-associated infections with FDG PET in patients with trauma: correlation with microbiologic results. Radiology 2003;226:391-8
   PubMed Web of Science ®Google Scholar
• Kalicke T, Schmitz A, Risse JH, et al. Fluorine-18 fluorodeoxyglucose PET in infectious bone diseases: results of histologically confirmed cases. Eur J Nucl Med 2000;27:524-8
   PubMedGoogle Scholar
• Bertagna F, Pizzocaro C, Biasiotto G, et al. (18)F-FDG-PET/CT findings in patients affected by spondylodiscitis. Hell J Nucl Med 2010;13:166-8
   PubMed Web of Science ®Google Scholar
• Nanni C, Errani C, Boriani L, et al. 68Ga-citrate PET/CT for evaluating patients with infections of the bone: preliminary results. J Nucl Med 2010;51:1932-6
   PubMed Web of Science ®Google Scholar
• Abdul H, Abdul N, Nordin A. Dual time point imaging of FDG PET/CT in a tuberculous spondylodiscitis. Biomed Imaging Interv J 2010;6:e18
   PubMedGoogle Scholar
• Ryoppy S, Jaaskelainen J, Rapola J, et al. Nonspecific diskitis in children. A nonmicrobial disease? Clin Orthop Relat Res 1993;297:95-9
   PubMed Web of Science ®Google Scholar
• Roblot F, Besnier JM, Juhel L, et al. Optimal duration of antibiotic therapy in vertebral osteomyelitis. Semin Arthritis Rheum 2007;36:269-77
   PubMed Web of Science ®Google Scholar
• Stengel D, Bauwens K, Sehouli J, et al. Systematic review and meta-analysis of antibiotic therapy for bone and joint infections. Lancet Infect Dis 2001;1:175-88
   PubMedGoogle Scholar
• Stengel D, Bauwens K, Sehouli J, et al. Systematic review and meta-analysis of emergency ultrasonography for blunt abdominal trauma. Br J Surg 2001;88:901-12
   PubMed Web of Science ®Google Scholar
• Coskun-Ari FF, Bosgelmez-Tinaz G. grlA and gyrA mutations and antimicrobial susceptibility in clinical isolates of ciprofloxacin-methicillin-resistant Staphylococcus aureus. Eur J Med Res 2008;13:366-70
   PubMed Web of Science ®Google Scholar
• Schrenzel J, Harbarth S, Schockmel G, et al. A randomized clinical trial to compare fleroxacin–rifampicin with flucloxacillin or vancomycin for the treatment of staphylococcal infection. Clin Infect Dis 2004;39:1285-92
   PubMed Web of Science ®Google Scholar
• Perlroth J, Kuo M, Tan J, et al. Adjunctive use of rifampin for the treatment of Staphylococcus aureus infections: a systematic review of the literature. Arch Intern Med 2008;168:805-19
   PubMedGoogle Scholar
• Livorsi DJ, Daver NG, Atmar RL, et al. Outcomes of treatment for hematogenous Staphylococcus aureus vertebral osteomyelitis in the MRSA ERA. J Infect 2008;57:128-31
   PubMed Web of Science ®Google Scholar
• Zimmerli W, Trampuz A, Ochsner PE. Prosthetic-joint infections. N Engl J Med 2004;351:1645-54
   PubMed Web of Science ®Google Scholar
• Steven S. Agabegi FAA, Harry N. Spinal orthoses. J Am Acad Orthop Surg 2010;18:657-67
   PubMed Web of Science ®Google Scholar
• White AA, Panjabi MM, Posner I, Edwards WT, et al. Spinal stability: evaluation and treatment. Instr Course Lect 1981;30:457-83
   PubMedGoogle Scholar
• Johnson RM HD, Simmons EF, Ramsby GR, et al. Cervical orthoses: a study comparing their effectiveness in restricting cervical motion in normal subjects. J Bone Joint Surg Am 1977;59:332-9
   PubMed Web of Science ®Google Scholar
• Gravin TM CG, Havey R, Flanagan P, et al. biomechanical analysis of cervical orthoses in flexion and extension: a comparison of cervical collars and cervical thoracic orthoses. J Rehabil Res Dev 2003;40:6527-37
   Google Scholar
• Denaro V, Di Martino A. The Role of Orthopaedic Surgery in Bone Metastases. In Santini D: Treatment of Bone Metastases. Guidelines, Italian Society of Medical Oncology (AIOM). Como, Italy: Tecnografica Edizioni Lomazzo, 2009
   Google Scholar
• Denaro V. Stenosis of the cervical spine. Ed. Springer-Verlag, Berlin 1991
   Google Scholar
• Leys D, Lesoin F, Viaud C, et al. Decreased morbidity from acute bacterial spinal epidural abscesses using computed tomography and nonsurgical treatment in selected patients. Ann Neurol 1985;17:350-5
   PubMed Web of Science ®Google Scholar
• Jeanneret B, Magerl F. Treatment of osteomyelitis of the spine using percutaneous suction/irrigation and percutaneous external spinal fixation. J Spinal Disord 1994;7:185-205
   PubMedGoogle Scholar
• Zarghooni K, Rollinghoff M, Sobottke R, et al. Treatment of spondylodiscitis. Int Orthop 2012;36:405-11
   PubMed Web of Science ®Google Scholar
• Hollis PH, Malis LI, Zappulla RA. Neurological deterioration after lumbar puncture below complete spinal subarachnoid block. J Neurosurg 1986;64:253-6
   PubMed Web of Science ®Google Scholar
• Denaro V, Di Martino A. Cervical spine surgery: an historical perspective. Clin Orthop Relat Res 2011;469:639-48
   PubMed Web of Science ®Google Scholar
• Moon MS, Woo YK, Lee KS, et al. Posterior instrumentation and anterior interbody fusion for tuberculous kyphosis of dorsal and lumbar spines. Spine (Phila Pa 1976) 1995;20:1910-16
   PubMed Web of Science ®Google Scholar
• Schimmer RC, Jeanneret C, Nunley PD, et al. Osteomyelitis of the cervical spine: a potentially dramatic disease. J Spinal Disord Tech 2002;15:110-17
   PubMed Web of Science ®Google Scholar
• Denaro V, Di Martino A, Papalia R, et al. Patients with cervical metastasis and neoplastic pachymeningitis are less likely to improve neurologically after surgery. Clin Orthop Relat Res 2011;469:708-14
   PubMed Web of Science ®Google Scholar
• Cadotte DW FM. Spinal cord injury. A systematic review of current treatment options. Clin Orthop Relat Res 2011;469:732-41
   PubMed Web of Science ®Google Scholar
• Liebergall M, Chaimsky G, Lowe J, et al. Pyogenic vertebral osteomyelitis with paralysis. Prognosis and treatment. Clin Orthop Relat Res 1991;269:142-50
   PubMed Web of Science ®Google Scholar
• Darouiche RO. Spinal epidural abscess. N Engl J Med 2006;355:2012-20
   PubMed Web of Science ®Google Scholar
• Heyde CE, Boehm H, El Saghir H, et al. Surgical treatment of spondylodiscitis in the cervical spine: a minimum 2-year follow-up. Eur Spine J 2006;15:1380-7
   PubMed Web of Science ®Google Scholar
• Robinson Y, Reinke M, Kayser R, et al. Postoperative multisegmental lumbar discitis treated by staged ventrodorsoventral intervention. Surg Infect (Larchmt) 2007;8:529-34
   PubMedGoogle Scholar
• Kuklo TR, Potter BK, Bell RS, et al. Single-stage treatment of pyogenic spinal infection with titanium mesh cages. J Spinal Disord Tech 2006;19:376-82
   PubMed Web of Science ®Google Scholar
• Ruf M, Stoltze D, Merk HR, et al. Treatment of vertebral osteomyelitis by radical debridement and stabilization using titanium mesh cages. Spine (Phila Pa 1976) 2007;32:E275-80
   PubMed Web of Science ®Google Scholar
• Korovessis P, Petsinis G, Koureas G, et al. Anterior surgery with insertion of titanium mesh cage and posterior instrumented fusion performed sequentially on the same day under one anesthesia for septic spondylitis of thoracolumbar spine: is the use of titanium mesh cages safe? Spine (Phila Pa 1976) 2006;31:1014-19
   PubMed Web of Science ®Google Scholar
• Robinson Y, Tschoeke SK, Finke T, et al. Successful treatment of spondylodiscitis using titanium cages: a 3-year follow-up of 22 consecutive patients. Acta Orthop 2008;79:660-4
   PubMed Web of Science ®Google Scholar
• Ha KY, Chung YG, Ryoo SJ. Adherence and biofilm formation of Staphylococcus epidermidis and Mycobacterium tuberculosis on various spinal implants. Spine (Phila Pa 1976) 2005;30:38-43
   PubMed Web of Science ®Google Scholar
• Klockner C, Valencia R. Sagittal alignment after anterior debridement and fusion with or without additional posterior instrumentation in the treatment of pyogenic and tuberculous spondylodiscitis. Spine (Phila Pa 1976) 2003;28:1036-42
   PubMed Web of Science ®Google Scholar
• Ha KY, Shin JH, Kim KW, et al. The fate of anterior autogenous bone graft after anterior radical surgery with or without posterior instrumentation in the treatment of pyogenic lumbar spondylodiscitis. Spine (Phila Pa 1976) 2007;32:1856-64
   PubMed Web of Science ®Google Scholar
• Korovessis P, Repantis T, Iliopoulos P, et al. Beneficial influence of titanium mesh cage on infection healing and spinal reconstruction in hematogenous septic spondylitis: a retrospective analysis of surgical outcome of twenty-five consecutive cases and review of literature. Spine (Phila Pa 1976) 2008;33:E759-67
   PubMedGoogle Scholar
• Govender S, Csimma C, Genant HK, et al. Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients. J Bone Joint Surg Am 2002;84:2123-34
   PubMed Web of Science ®Google Scholar
• Burkus JK, Sandhu HS, Gornet MF, et al. Use of rhBMP-2 in combination with structural cortical allografts: clinical and radiographic outcomes in anterior lumbar spinal surgery. J Bone Joint Surg Am 2005;87:1205-12
   PubMed Web of Science ®Google Scholar
• Burkus JK. Bone morphogenetic proteins in anterior lumbar interbody fusion: old techniques and new technologies. J Neurosurg Spine 2004;1(3):254-60
   PubMed Web of Science ®Google Scholar
• Allen RT, Lee YP, Stimson E, et al. Bone morphogenetic protein-2 (BMP-2) in the treatment of pyogenic vertebral osteomyelitis. Spine (Phila Pa 1976) 2007;32:2996-3006
   PubMed Web of Science ®Google Scholar
• Aryan HE, Acosta FL, Ames CP. Corpectomy followed by the placement of instrumentation with titanium cages and recombinant human bone morphogenetic protein-2 for vertebral osteomyelitis. J Neurosurg Spine 2007;6:23-30
   PubMed Web of Science ®Google Scholar
• Vadala G, Di Martino A, Tirindelli MC, et al. Use of autologous bone marrow cells concentrate enriched with platelet-rich fibrin on corticocancellous bone allograft for posterolateral multilevel cervical fusion. J Tissue Eng Regen Med 2008;2:515-20
   PubMed Web of Science ®Google Scholar