The systemic effect of bromhexine (‘Bisolvon’) in normal subjects

Reference

• Amin, A. H., and Mehta, D. R., (1959). A bronchodilator alkaloid (vasicinone) from Adhatoda vasica Nees. Nature, 184, 1317.1. Amin, A. H., and Mehta, D. R., (1959). A bronchodilator alkaloid (vasicinone) from Adhatoda vasica Nees. Nature, 184, 1317.
   PubMed Web of Science ®Google Scholar
• Boyd, E. M., Godi, I., and Krijnen, C. J., (1966). The acute oral toxicity of a vasicin derivative. J. New Drugs, 6, 269.2. Boyd, E. M., Godi, I., and Krijnen, C. J., (1966). The acute oral toxicity of a vasicin derivative. J. New Drugs, 6, 269.
   PubMedGoogle Scholar
• Bruce, R. A., and Kumar, V., (1968). The effect of a derivative of vasicine on bronchial mucus. Brit. J. clin. Pract., 22, 289.3. Bruce, R. A., and Kumar, V., (1968). The effect of a derivative of vasicine on bronchial mucus. Brit. J. clin. Pract., 22, 289.
   PubMedGoogle Scholar
• Burgi, H., (1964). Mucoproteins and sputum viscosity. Lancet, 2, 644.4. Burgi, H., (1964). Mucoproteins and sputum viscosity. Lancet, 2, 644.
   PubMed Web of Science ®Google Scholar
• Hamilton, W. F. D., Palmer, K. N. V., and Gent, M., (1970). Expectorant action of bromhexine in chronic obstructive bronchitis. Brit. med. J., 3, 260.5. Hamilton, W. F. D., Palmer, K. N. V., and Gent, M., (1970). Expectorant action of bromhexine in chronic obstructive bronchitis. Brit. med. J., 3, 260.
   PubMed Web of Science ®Google Scholar
• Gent, M., Knowlson, P. A., and Prime, F. J., (1969). Effect of bromhexine on ventilatory capacity in patients with a variety of chest diseases. Lancet, 2, 1094.6. Gent, M., Knowlson, P. A., and Prime, F. J., (1969). Effect of bromhexine on ventilatory capacity in patients with a variety of chest diseases. Lancet, 2, 1094.
   PubMed Web of Science ®Google Scholar
• Flavell Matts, S. G., (1969). Clinical experience of Bisolvon in 220 cases of chest disease. Brit. J. clin. Pract., 23, 501.7. Flavell Matts, S. G., (1969). Clinical experience of Bisolvon in 220 cases of chest disease. Brit. J. clin. Pract., 23, 501.
   PubMedGoogle Scholar
• Christensen, F., Kjer, J., Ryskjaer, S., and Arseth-Hansen, P., (1970). Bromhexine in chronic bronchitis. Brit. med. J., 4, 117.8. Christensen, F., Kjer, J., Ryskjaer, S., and Arseth-Hansen, P., (1970). Bromhexine in chronic bronchitis. Brit. med. J., 4, 117.
   PubMed Web of Science ®Google Scholar
• Langlands, J., (1970). Double-blind clinical trial of bromhexine as a mucolytic drug in chronic bronchitis. Lancet, 1, 448.9. Langlands, J., (1970). Double-blind clinical trial of bromhexine as a mucolytic drug in chronic bronchitis. Lancet, 1, 448.
   PubMed Web of Science ®Google Scholar
• Boyd, E. M., and Sheppard, P., (1966). On the expectorant activity of Bisolvon. Arch. int. Pharmacodyn., 163, 283.10. Boyd, E. M., and Sheppard, P., (1966). On the expectorant activity of Bisolvon. Arch. int. Pharmacodyn., 163, 283.
   Google Scholar
• Clarke, S. W., Craig, G. M., and Makin, E. J. B., (1972). Clinical trial of bromhexine in severe chronic bronchitics during winter. Thorax, 27, 429.11. Clarke, S. W., Craig, G. M., and Makin, E. J. B., (1972). Clinical trial of bromhexine in severe chronic bronchitics during winter. Thorax, 27, 429.
   PubMed Web of Science ®Google Scholar
• Moore, G. R., (1970). An improved automated method for the determination of urea. J. med. Lab. Technol., 27, 139.12. Moore, G. R., (1970). An improved automated method for the determination of urea. J. med. Lab. Technol., 27, 139.
   PubMedGoogle Scholar
• Mabry, C. C., Gevedon, R. E., Rocckel, I. E., and Gochman, M., (1966). Automated submicro chemistries: a system of rapid submicro chemistry analysis for the measurement of sodium, potassium, chloride, carbon dioxide, sugar, urea nitrogen, total and direct-reacting bilirubins and total protein. Amer. J. clin. Path., 46, 265.13. Mabry, C. C., Gevedon, R. E., Rocckel, I. E., and Gochman, M., (1966). Automated submicro chemistries: a system of rapid submicro chemistry analysis for the measurement of sodium, potassium, chloride, carbon dioxide, sugar, urea nitrogen, total and direct-reacting bilirubins and total protein. Amer. J. clin. Path., 46, 265.
   Google Scholar
• Barry, K. G., McLaurin, A. W., and Parnell, B. L., (1960). A practical temperature-compensated hand refractometer (The TS Meter): its clinical use and application in estimation of serum proteins. J. Lab. clin. Med., 55, 803.14. Barry, K. G., McLaurin, A. W., and Parnell, B. L., (1960). A practical temperature-compensated hand refractometer (The TS Meter): its clinical use and application in estimation of serum proteins. J. Lab. clin. Med., 55, 803.
   PubMed Web of Science ®Google Scholar
• Northam, B. E., and Widdowson, G. M., (1967). Determination of serum albumin by auto-analyser using bromocresol Green. Association of Clinical Biochemists Scientific and Technical Committee. Technical Bulletin No. 11.15. Northam, B. E., and Widdowson, G. M., (1967). Determination of serum albumin by auto-analyser using bromocresol Green. Association of Clinical Biochemists Scientific and Technical Committee. Technical Bulletin. No. 11.
   Google Scholar
• Morganstern, S., Oklander, M., Auerbach, J., and Klein, B., (1966). Automated determination of serum glutamic oxaloacetic transaminase. Clin. Chem., 12, 95.16. Morganstern, S., Oklander, M., Auerbach, J., and Klein, B., (1966). Automated determination of serum glutamic oxaloacetic transaminase. Clin. Chem., 12, 95.
   PubMed Web of Science ®Google Scholar
• Morganstern, S., Kersler, G., Auerbach, J., Flor, R. V., and Klein, B., (1965). An automated p-nitrophenylphosphate serum alkaline phosphatase procedure for the autoanalyser. Clin. Chem., 11, 876.17. Morganstern, S., Kersler, G., Auerbach, J., Flor, R. V., and Klein, B., (1965). An automated p-nitrophenylphosphate serum alkaline phosphatase procedure for the autoanalyser. Clin. Chem., 11, 876.
   PubMedGoogle Scholar
• Kessler, G., and Wolfman, M., (1964). An automated procedure for the simultaneous determination of calcium and phosphorus. Clin. Chem., 10, 686.18. Kessler, G., and Wolfman, M., (1964). An automated procedure for the simultaneous determination of calcium and phosphorus. Clin. Chem., 10, 686.
   PubMed Web of Science ®Google Scholar
• Phosphorus Determination. Technicon Method File N-40.19. , Phosphorus Determination. Technicon Method File N-40.
   Google Scholar
• Creatinine Determination. Technicon Method File N-11.20. , Creatinine Determination. Technicon Method File N-11.
   Google Scholar
• Francey, R. J., and Amador, E., (1968). Serum cholesterol measurement based on ethanol extraction and ferric chloride-sulphuric acid. Clin. chim. Acta., 21, 255.21. Francey, R. J., and Amador, E., (1968). Serum cholesterol measurement based on ethanol extraction and ferric chloride-sulphuric acid. Clin. chim. Acta., 21, 255.
   PubMed Web of Science ®Google Scholar
• Simmons, N. A., (1968). An automated method for serum bilirubin determination. J. clin. Path., 21, 196.22. Simmons, N. A., (1968). An automated method for serum bilirubin determination. J. clin. Path., 21, 196.
   PubMed Web of Science ®Google Scholar
• Pennock, C. A., Moore, G. R., and Hoyle, M. D., (1970). Estimation of hydroxyproline in urine. J. med. Lab. Technol., 27, 302.23. Pennock, C. A., Moore, G. R., and Hoyle, M. D., (1970). Estimation of hydroxyproline in urine. J. med. Lab. Technol., 27, 302.
   PubMedGoogle Scholar
• Di Ferrante, N. M., (1967). The measurement of urinary mucopolysaccharides. Analyt. Biochem., 21, 98.24. Di Ferrante, N. M., (1967). The measurement of urinary mucopolysaccharides. Analyt. Biochem., 21, 98.
   PubMed Web of Science ®Google Scholar
• Bitter, T., and Muir, H. M., (1962). A modified uronic acid carbazole reaction. Analyt. Biochem., 4, 330.25. Bitter, T., and Muir, H. M., (1962). A modified uronic acid carbazole reaction. Analyt. Biochem., 4, 330.
   PubMed Web of Science ®Google Scholar
• Snedecor, G. W., and Cochran, W. G., (1967). Statistical Methods, Sixth Edition.. Iowa State University Press.26. Snedecor, G. W., and Cochran, W. G., (1967). Statistical Methods, Sixth Edition. Iowa State University Press.
   Google Scholar
• McKusick, V. A., (1969). The nosology of the mucopoly - saccharidoses. Amer. J. Med., 47, 730.27. McKusick, V. A., (1969). The nosology of the mucopoly - saccharidoses. Amer. J. Med., 47, 730.
   PubMed Web of Science ®Google Scholar
• Dorfman, A., and Matalon, R., (1969). The Hurler and Hunter Syndromes. Amer. J. Med., 47, 691.28. Dorfman, A., and Matalon, R., (1969). The Hurler and Hunter Syndromes. Amer. J. Med., 47, 691.
   PubMed Web of Science ®Google Scholar
• Hers, H. G., and van Hoof, F., (1969). Lysosomes and mucopolysaccharidoses. Biochem. J., 115, 34.29. Hers, H. G., and van Hoof, F., (1969). Lysosomes and mucopolysaccharidoses. Biochem. J., 115, 34.
   Google Scholar
• Gieseking, R., and Baldamus, U., (1968). Electron-microscopic findings in human bronchial mucosa after treatment with Bisolvon. Beitr. Klin. Tuberk., 137, 1.30. Gieseking, R., and Baldamus, U., (1968). Electron-microscopic findings in human bronchial mucosa after treatment with Bisolvon. Beitr. Klin. Tuberk., 137, 1.
   PubMedGoogle Scholar
• Baldamus, U., and Gries, C., (1965). The behaviour of mucopolysaccharides, mucoproteins and the nitrogen of sputum under the action of N-Cyclohexyl-N-Methyl-(2-amino-3, 5-dibrombenzyl-) ammonium chloride. Therap. Umschau., 22, 362.31. Baldamus, U., and Gries, C., (1965). The behaviour of mucopolysaccharides, mucoproteins and the nitrogen of sputum under the action of N-Cyclohexyl-N-Methyl-(2-amino-3, 5-dibrombenzyl-) ammonium chloride. Therap. Umschau., 22, 362.
   PubMedGoogle Scholar
• Boehringer Ingelheim Medical Dept. Files, Personal communication..32. Personal communication. Boehringer Ingelheim Medical Dept. Files.
   Google Scholar