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Research Article

Assessing the impact of a mushroom-derived food ingredient on vitamin D levels in healthy volunteers

Jorge Marques Pinto1 Cambridge Centre for Sport and Exercise Sciences, School of Psychology and Sport ScienceAnglia Ruskin UniversityCompass House, East RoadCB1 1PTCambridgeUKCorrespondence[email protected]

Viviane Merzbach1 Cambridge Centre for Sport and Exercise Sciences, School of Psychology and Sport ScienceAnglia Ruskin UniversityCompass House, East RoadCB1 1PTCambridgeUK

Ashley G. B. Willmott1 Cambridge Centre for Sport and Exercise Sciences, School of Psychology and Sport ScienceAnglia Ruskin UniversityCompass House, East RoadCB1 1PTCambridgeUK

Jose Antonio2 Exercise and Sport ScienceNova Southeastern-Florida UniversityDavieFLUSA

Justin Roberts1 Cambridge Centre for Sport and Exercise Sciences, School of Psychology and Sport ScienceAnglia Ruskin UniversityCompass House, East RoadCB1 1PTCambridgeUKCorrespondence[email protected]

https://orcid.org/0000-0002-3169-2041

Article: 54 | Published online: 01 Apr 2022

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https://doi.org/10.1186/s12970-020-00387-0
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ShanelyRANiemanDCKnabAMGillittNDMeaneyMPJinF et al Influence of vitamin D mushroom powder supplementation on exercise-induced muscle damage in vitamin D insufficient high school athletesJ Sports Sci201432 7 670 679 https://doi.org/10.1080/02640414.2013.847279 24117183
PubMed Web of Science ®Google Scholar
HolickMFVitamin D deficiencyN Engl J Med2007357 3 266 281 1:CAS:528:DC%2BD2sXotVejsbc%3D https://doi.org/10.1056/NEJMra070553 17634462
PubMed Web of Science ®Google Scholar
HolickMFBinkleyNCBischoff-FerrariHAGordonCMHanleyDAHeaneyRP et al Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guidelineJ Clin Endocrinol Metab201196 7 1911 1930 1:CAS:528:DC%2BC3MXptlSku7o%3D https://doi.org/10.1210/jc.2011-0385 21646368
PubMed Web of Science ®Google Scholar
WilsonLRTripkovicLHartKHLanham-NewSAVitamin D deficiency as a public health issue: using vitamin D 2 or vitamin D 3 in future fortification strategiesProc Nutr Soc201776 3 392 399 https://doi.org/10.1017/S0029665117000349 28347378
PubMed Web of Science ®Google Scholar
ZajacICavuotoPDanthiirVWittertGAKrauseDLawsonL et al Study protocol: a randomised, double blinded, placebo-controlled clinical trial testing the effects of a vitamin D-enriched mushroom supplement on cognitive performance and mood in healthy elderly adultsHealthy Aging Res20165 1 14 https://doi.org/10.1097/01.HXR.0000511866.70301.d6
Google Scholar
BikleDDVitamin D metabolism, mechanism of action, and clinical applicationsChem Biol201421 3 319 329 1:CAS:528:DC%2BC2cXisFehu7k%3D https://doi.org/10.1016/j.chembiol.2013.12.016 3968073 3968073
PubMedGoogle Scholar
HollisBWComparison of equilibrium and disequilibrium assay conditions for ergocalciferol, cholecalciferol and their major metabolitesJ Steroid Biochem198421 1 81 86 1:CAS:528:DyaL2cXltVKrt7k%3D https://doi.org/10.1016/0022-4731(84)90063-3 6087030
PubMedGoogle Scholar
TsugawaNNakagawaKKawamotoYTachibanaYHayashiTOzonoK et al Biological activity profiles of 1α, 25-Dihydroxyvitamin D2, D3, D4, D7, and 24-Epi-1α, 25-dihydroxyvitamin D2Biol Pharm Bull199922 4 371 377 1:CAS:528:DyaK1MXislSrs7Y%3D https://doi.org/10.1248/bpb.22.371 10328556
PubMedGoogle Scholar
AngelineMEGeeAOShindleMWarrenRFRodeoSAThe effects of vitamin D deficiency in athletesAm J Sports Med201341 2 461 464 https://doi.org/10.1177/0363546513475787 23371942
PubMed Web of Science ®Google Scholar
CardwellGBornmanJFJamesAPBlackLJA review of mushrooms as a potential source of dietary vitamin DNutrients.201810 10 1498 1:CAS:528:DC%2BC1MXmsl2gu7s%3D https://doi.org/10.3390/nu10101498 6213178
PubMed Web of Science ®Google Scholar
BatesBCoxLNicholsonS National diet and nutrition survey results from years 5 and 6 (combined) of the rolling programme (2012/2013–2013/2014)2016 London Public Health England and Food Standards Agency
Google Scholar
O’MahonyLStepienMGibneyMJNugentAPBrennanLThe potential role of vitamin D enhanced foods in improving vitamin D statusNutrients.20113 12 1023 1041 1:CAS:528:DC%2BC38XjtF2ltg%3D%3D https://doi.org/10.3390/nu3121023 22292109 3260490
PubMedGoogle Scholar
AthertonKBerryDJParsonsTMacfarlaneGJPowerCHypponenEVitamin D and chronic widespread pain in a white middle-aged british population: evidence from a cross-sectional population surveyAnn Rheum Dis200968 817 822 1:CAS:528:DC%2BD1MXotVCjtLg%3D https://doi.org/10.1136/ard.2008.090456 18697776
PubMed Web of Science ®Google Scholar
CloseGLRussellJCobleyJNOwensDWilsonGGregsonW et al Assessment of vitamin D concentration in non-supplemented professional athletes and healthy adults during the winter months in the UK: implications for skeletal muscle functionJ Sports Sci201331 4 344 353 1:STN:280:DC%2BC3s%2Fms1KlsA%3D%3D https://doi.org/10.1080/02640414.2012.733822 23083379
PubMed Web of Science ®Google Scholar
WillisKSPetersonNJLarson-MeyerDEShould we be concerned about the vitamin D status of athletes?Int J Sport Nutr Exerc Metab200818 2 204 224 1:CAS:528:DC%2BD1cXmtFKrtrg%3D https://doi.org/10.1123/ijsnem.18.2.204 18458363
PubMed Web of Science ®Google Scholar
DahlquistDTDieterBPKoehleMSPlausible ergogenic effects of vitamin D on athletic performance and recoveryJ Int Soc Sports Nutr201512 1 33 1:CAS:528:DC%2BC1MXltFyhsg%3D%3D https://doi.org/10.1186/s12970-015-0093-8 26288575 4539891
PubMedGoogle Scholar
WillisKSSmithDTBroughtonKSLarson-MeyerDEVitamin D status and biomarkers of inflammation in runnersOpen Access J Sports Med20123 35 https://doi.org/10.2147/OAJSM.S31022 24198585 3781897
PubMedGoogle Scholar
WilliamsonCButtrissJ EuroFIR: food databank systems, delivering information to researchers, consumers and industry2007
Google Scholar
Scientific Advisory Committee on Nutrition Vitamin D and health report2016 London The Stationary Office https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/537616/SACN_Vitamin_D_and_Health_report.pdf. Accessed 21 Apr 2020
Google Scholar
MehrotraACalvoMBeelmanRLevyESiutyJKalarasM et al Bioavailability of vitamin D 2 from enriched mushrooms in prediabetic adults: a randomized controlled trialEur J Clin Nutr201468 10 1154 1160 1:CAS:528:DC%2BC2cXhtlKktrvM https://doi.org/10.1038/ejcn.2014.157 25117997
PubMedGoogle Scholar
BiancuzzoRMYoungABibuldDCaiMHWinterMRKleinEK et al Fortification of orange juice with vitamin D(2) or vitamin D(3) is as effective as an oral supplement in maintaining vitamin D status in adultsAm J Clin Nutr201091 6 1621 1626 1:CAS:528:DC%2BC3cXmslKkt7Y%3D https://doi.org/10.3945/ajcn.2009.27972 20427729 2869510
PubMed Web of Science ®Google Scholar
Nascimento VLVd, Bermúdez VMS, Oliveira ALLd, Kleinberg MN, Ribeiro RdTM, Abreu RFAd, et al.Characterization of a hydrolyzed oil obtained from fish waste for nutraceutical applicationFood Sci Technol201535 2 321 325 https://doi.org/10.1590/1678-457x.6583
Web of Science ®Google Scholar
TaofiqOFernandesÂBarrosLBarreiroMFFerreiraICUV-irradiated mushrooms as a source of vitamin D2: a reviewTrends Food Sci Technol201770 82 94 1:CAS:528:DC%2BC2sXhsleks7fJ https://doi.org/10.1016/j.tifs.2017.10.008
Web of Science ®Google Scholar
CashmanKDKielyMSeamansKMUrbainPEffect of ultraviolet light–exposed mushrooms on vitamin D status: liquid chromatography–tandem mass spectrometry reanalysis of biobanked sera from a randomized controlled trial and a systematic review plus meta-analysisJ Nutr2016146 3 565 575 1:CAS:528:DC%2BC28XhtVOls7fP https://doi.org/10.3945/jn.115.223784 26865648
PubMedGoogle Scholar
Keegan R-JHLZBoguszJMWilliamsJEHolickMFPhotobiology of vitamin D in mushrooms and its bioavailability in humansDermatoendocrinol.20135 1 165 176 1:CAS:528:DC%2BC2cXjtVOltLc%3D https://doi.org/10.4161/derm.23321
Google Scholar
Stepien M, O'Mahony L, O'Sullivan A, Collier J, Fraser WD, Gibney MJ, et al. Effect of supplementation with vitamin D2-enhanced mushrooms on vitamin D status in healthy adults. J Nutr Sci. 2013;2. https://doi.org/https://doi.org/10.1017/jns.2013.22.
Google Scholar
UrbainPSinglerFIhorstGBiesalskiH-KBertzHBioavailability of vitamin D 2 from UV-B-irradiated button mushrooms in healthy adults deficient in serum 25-hydroxyvitamin D: a randomized controlled trialEur J Clin Nutr201165 8 965 971 1:CAS:528:DC%2BC3MXps12ks7w%3D https://doi.org/10.1038/ejcn.2011.53 21540874
PubMedGoogle Scholar
HoughtonLAViethRThe case against ergocalciferol (vitamin D2) as a vitamin supplementAm J Clin Nutr200684 4 694 697 1:CAS:528:DC%2BD28XhtFWgtr3N https://doi.org/10.1093/ajcn/84.4.694 17023693
PubMed Web of Science ®Google Scholar
AloiaJDhaliwalRMikhailMShiehAStolbergARagoliaL et al Free 25 (OH) D and calcium absorption, PTH, and markers of bone turnoverJ Clin Endocrinol Metab2015100 11 4140 4145 1:CAS:528:DC%2BC28Xjt1Ghu7o%3D https://doi.org/10.1210/jc.2015-2548 26312580 4702446
PubMedGoogle Scholar
ArmasLAHollisBWHeaneyRPVitamin D2 is much less effective than vitamin D3 in humansJ Clin Endocrinol Metab200489 11 5387 5391 1:CAS:528:DC%2BD2cXhtVSisb%2FL https://doi.org/10.1210/jc.2004-0360 15531486
PubMed Web of Science ®Google Scholar
GlendenningPChewGTInderjeethCATarantoMFraserWDCalculated free and bioavailable vitamin D metabolite concentrations in vitamin D-deficient hip fracture patients after supplementation with cholecalciferol and ergocalciferolBone.201356 2 271 275 1:CAS:528:DC%2BC3sXhtlWhtbnM https://doi.org/10.1016/j.bone.2013.06.012 23792937
PubMedGoogle Scholar
HammamiMMYusufADifferential effects of vitamin D2 and D3 supplements on 25-hydroxyvitamin D level are dose, sex, and time dependent: a randomized controlled trialBMC Endocr Disord201717 1 12 1:CAS:528:DC%2BC1cXkvVSntb0%3D https://doi.org/10.1186/s12902-017-0163-9 28231782 5324269
PubMedGoogle Scholar
HeaneyRPReckerRRGroteJHorstRLArmasLAVitamin D3 is more potent than vitamin D2 in humansJ Clin Endocrinol Metab201196 3 E447 EE52 1:CAS:528:DC%2BC3MXjvFahtLo%3D https://doi.org/10.1210/jc.2010-2230 21177785
PubMed Web of Science ®Google Scholar
ItkonenSTSkaffariESaaristoPSaarnioEMErkkolaMJakobsenJ et al Effects of vitamin D2-fortified bread v. supplementation with vitamin D2 or D3 on serum 25-hydroxyvitamin D metabolites: an 8-week randomised-controlled trial in young adult Finnish womenBr J Nutr2016115 7 1232 1239 1:CAS:528:DC%2BC28XktVyks7o%3D https://doi.org/10.1017/S0007114516000192 26864127
PubMed Web of Science ®Google Scholar
LehmannUHircheFStanglGIHinzKWestphalSDierkesJBioavailability of vitamin D2 and D3 in healthy volunteers, a randomized placebo-controlled trialJ Clin Endocrinol Metab201398 11 4339 4345 1:CAS:528:DC%2BC3sXhsl2msrzO https://doi.org/10.1210/jc.2012-4287 24001747
PubMed Web of Science ®Google Scholar
LoganVFGrayARPeddieMCHarperMJHoughtonLALong-term vitamin D 3 supplementation is more effective than vitamin D 2 in maintaining serum 25-hydroxyvitamin D status over the winter monthsBr J Nutr2013109 6 1082 1088 1:CAS:528:DC%2BC3sXjvVakt7w%3D https://doi.org/10.1017/S0007114512002851 23168298
PubMedGoogle Scholar
MartineauARThummelKEWangZJolliffeDABoucherBJGriffinSJ et al Differential effects of Oral boluses of vitamin D2 vs vitamin D3 on vitamin D metabolism: a randomized controlled trialJ Clin Endocrinol Metab2019104 12 5831 5839 https://doi.org/10.1210/jc.2019-00207 31199458 6797055
PubMedGoogle Scholar
OliveriBMastagliaSRBritoGMSeijoMKellerGASomozaJ et al Vitamin D3 seems more appropriate than D2 to sustain adequate levels of 25OHD: a pharmacokinetic approachEur J Clin Nutr201569 6 697 702 1:CAS:528:DC%2BC2MXks1alsrc%3D https://doi.org/10.1038/ejcn.2015.16 25782422
PubMedGoogle Scholar
ShiehAChunRFMaCWitzelSMeyerBRafisonB et al Effects of high-dose vitamin D2 versus D3 on Total and free 25-Hydroxyvitamin D and markers of calcium balanceJ Clin Endocrinol Metab2016101 8 3070 3078 1:CAS:528:DC%2BC28XhvVSksrrF https://doi.org/10.1210/jc.2016-1871 27192696 4971338
PubMed Web of Science ®Google Scholar
TrangHMColeDRubinLAPierratosASiuSViethREvidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2Am J Clin Nutr199868 4 854 858 1:CAS:528:DyaK1cXmsV2gs78%3D https://doi.org/10.1093/ajcn/68.4.854 9771862
PubMed Web of Science ®Google Scholar
TripkovicLLambertHHartKSmithCPBuccaGPensonS et al Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysisAm J Clin Nutr201295 6 1357 1364 1:CAS:528:DC%2BC38XnslWkurY%3D https://doi.org/10.3945/ajcn.111.031070 22552031 3349454
PubMed Web of Science ®Google Scholar
TripkovicLWilsonLRHartKJohnsenSde LusignanSSmithCP et al Daily supplementation with 15 mug vitamin D2 compared with vitamin D3 to increase wintertime 25-hydroxyvitamin D status in healthy south Asian and white European women: a 12-wk randomized, placebo-controlled food-fortification trialAm J Clin Nutr2017106 2 481 490 1:CAS:528:DC%2BC1cXht1Wntr0%3D https://doi.org/10.3945/ajcn.116.138693 28679555
PubMed Web of Science ®Google Scholar
BinkleyNGemarDEngelkeJGangnonRRamamurthyRKruegerD et al Evaluation of ergocalciferol or cholecalciferol dosing, 1,600 IU daily or 50,000 IU monthly in older adultsJ Clin Endocrinol Metab201196 4 981 988 1:CAS:528:DC%2BC3MXltF2qt7k%3D https://doi.org/10.1210/jc.2010-0015 21289249 3417158
PubMedGoogle Scholar
HolickMFBiancuzzoRMChenTCKleinEKYoungABibuldD et al Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin DJ Clin Endocrinol Metab200893 3 677 681 1:CAS:528:DC%2BD1cXjsFyntL4%3D https://doi.org/10.1210/jc.2007-2308 18089691
PubMed Web of Science ®Google Scholar
NimitphongHSaetungSChanprasertyotinSChailurkitLOOngphiphadhanakulBChanges in circulating 25-hydroxyvitamin D according to vitamin D binding protein genotypes after vitamin D(3) or D(2)supplementationNutr J201312 39 1:CAS:528:DC%2BC3sXotFCmtr0%3D https://doi.org/10.1186/1475-2891-12-39 23556437 3637219
PubMedGoogle Scholar
Taylor K. Department of Biochemistry & Immunology – Index: ADD.BIO 34143. Addenbrooke’s Hospital. Cambridge University Hospitals NHS Foundation Trust. Directorate of Pathology. 25-Hydroxy Vitamin D3 / D2 by LC-MS/MS SOP – Version: 3.1.
Google Scholar
SpiroAButtrissJVitamin D: An overview of vitamin D status and intake in EuropeNutr Bull201439 4 322 350 1:STN:280:DC%2BC2svpvVCksQ%3D%3D https://doi.org/10.1111/nbu.12108 25635171 4288313
PubMedGoogle Scholar
ComynsTFlanaganEPApplications of the session rating of perceived exertion system in professional rugby unionStrength Cond J201335 6 78 85 https://doi.org/10.1519/SSC.0000000000000015
Web of Science ®Google Scholar
FosterCFlorhaugJAFranklinJGottschallLHrovatinLAParkerS et al A new approach to monitoring exercise trainingJ Strength Cond Res200115 1 109 115 1:STN:280:DC%2BD3Mnmt12qsA%3D%3D https://doi.org/10.1519/1533-4287(2001)015<0109:anatme>2.0.co;2 11708692
PubMed Web of Science ®Google Scholar
TripkovicLWilsonLLanham-NewSVitamin D2 vs. vitamin D3: they are not one and the sameNutr Bull201742 4 331 337 https://doi.org/10.1111/nbu.12293
Web of Science ®Google Scholar
StephensenCBZerofskyMBurnettDJLinY-pHammockBDHallLM et al Ergocalciferol from mushrooms or supplements consumed with a standard meal increases 25-hydroxyergocalciferol but decreases 25-hydroxycholecalciferol in the serum of healthy adultsJ Nutr2012142 7 1246 1252 1:CAS:528:DC%2BC38XpsFWmtbs%3D https://doi.org/10.3945/jn.112.159764 22623385
PubMed Web of Science ®Google Scholar
LotitoATeramotoMCheungMBeckerKSukumarDSerum parathyroid hormone responses to vitamin D supplementation in overweight/obese adults: a systematic review and meta-analysis of randomized clinical trialsNutrients.20179 3 241 1:CAS:528:DC%2BC1cXmtV2ms7Y%3D https://doi.org/10.3390/nu9030241 5372904
Web of Science ®Google Scholar
JonesKSAssarSHarnpanichDBouillonRLambrechtsDPrenticeA et al 25(OH)D2 half-life is shorter than 25(OH)D3 half-life and is influenced by DBP concentration and genotypeJ Clin Endocrinol Metab201499 9 3373 3381 1:CAS:528:DC%2BC2cXhs1enur3K https://doi.org/10.1210/jc.2014-1714 24885631 4207933
PubMed Web of Science ®Google Scholar
WeatherOnline. Cambridge UV Index: 05.02.2019–30.04.2019. https://www.weatheronline.co.uk/weather/maps/city. Accessed 14 June 2019.
Google Scholar
CardosoSSantosAGuerraRSSousaASPadrãoPMoreiraP et al Association between serum 25-hidroxyvitamin D concentrations and ultraviolet index in Portuguese older adults: a cross-sectional studyBMC Geriatr201717 1 1 11 https://doi.org/10.1186/s12877-017-0644-8
Google Scholar
CashmanKDKinsellaMMcNultyBAWaltonJGibneyMJFlynnA et al Dietary vitamin D 2–a potentially underestimated contributor to vitamin D nutritional status of adults?Br J Nutr2014112 2 193 202 1:CAS:528:DC%2BC2cXhtVWmtrzK https://doi.org/10.1017/S0007114514000725 24780068
PubMed Web of Science ®Google Scholar
PrinceSAAdamoKBHamelMEHardtJGorberSCTremblayMA comparison of direct versus self-report measures for assessing physical activity in adults: a systematic reviewInt J Behav Nutr Phys Act20085 1 56 https://doi.org/10.1186/1479-5868-5-56 18990237 2588639
PubMed Web of Science ®Google Scholar
BouillonRVerlindenLVerstuyfAIs vitamin D2 really bioequivalent to vitamin D3?Endocrinol.2016157 9 3384 3387 1:CAS:528:DC%2BC28XhvVGks7rJ https://doi.org/10.1210/en.2016-1528
Web of Science ®Google Scholar

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