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Effect of sodium bicarbonate contribution on energy metabolism during exercise: a systematic review and meta-analysis

Jorge Lorenzo Calvo1 Faculty of Physical Activity and Sport scienceUniversidad Politécnica de MadridMadridSpainCorrespondence[email protected]

Huanteng Xu2 Faculty of Sport SciencesUniversidad Europea de MadridMadridSpainCorrespondence[email protected]

https://orcid.org/0000-0002-9516-9380

Daniel Mon-López1 Faculty of Physical Activity and Sport scienceUniversidad Politécnica de MadridMadridSpain

Helios Pareja-Galeano2 Faculty of Sport SciencesUniversidad Europea de MadridMadridSpain

Sergio Lorenzo Jiménez3 Centre for Sport StudiesRey Juan Carlos UniversityFuenlabradaSpain

Article: 11 | Published online: 01 Apr 2022

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https://doi.org/10.1186/s12970-021-00410-y
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References

Kenney WL, Wilmore JH, and Costill DL: Physiology of sport and exercise: Human kinetics; 2015(Series Editor).
Google Scholar
MacLaren D and Morton J: Biochemistry for sport and exercise metabolism: John Wiley & Sons; 2011(Series Editor).
Google Scholar
SahlinKMuscle energetics during explosive activities and potential effects of nutrition and trainingSports Med201444 167 173 4213384 https://doi.org/10.1007/s40279-014-0256-9
PubMed Web of Science ®Google Scholar
ZinnerCWahlPAchtzehnS et al Effects of bicarbonate ingestion and high intensity exercise on lactate and h +−ion distribution in different blood compartmentsEur J Appl Physiol2011111 1641 1648 1:CAS:528:DC%2BC3MXhtFKqs7%2FE 21197542 https://doi.org/10.1007/s00421-010-1800-4 21197542
PubMed Web of Science ®Google Scholar
JuelCCurrent aspects of lactate exchange: lactate/h+ transport in human skeletal muscleEur J Appl Physiol200186 12 16 1:CAS:528:DC%2BD3MXotVymur8%3D 11820315 https://doi.org/10.1007/s004210100517 11820315
PubMedGoogle Scholar
Burke LM: Practical considerations for bicarbonate loading and sports performance. In Nutritional coaching strategy to modulate training efficiency. Volume 75. Edited by Tipton KD and VanLoon LJC; 2013:15–26.
Google Scholar
CarrAJHopkinsWGGoreCJEffects of acute alkalosis and acidosis on performance: a meta-analysisSports Med201141 801 814 21923200 https://doi.org/10.2165/11591440-000000000-00000 21923200
PubMed Web of Science ®Google Scholar
CameronSLMcLay-CookeRTBrownRC et al Increased blood ph but not performance with sodium bicarbonate supplementation in elite rugby union playersInt J Sport Nutr Exerc Metab201020 307 321 1:CAS:528:DC%2BC3cXhsFyhurrN 20739719 https://doi.org/10.1123/ijsnem.20.4.307 20739719
PubMed Web of Science ®Google Scholar
CarrAJSlaterGJGoreCJ et al Effect of sodium bicarbonate on [hco3 -], ph, and gastrointestinal symptomsInternational Journal of Sport Nutrition & Exercise Metabolism201121 189 194 1:CAS:528:DC%2BC3MXos1SnsLw%3D https://doi.org/10.1123/ijsnem.21.3.189
PubMed Web of Science ®Google Scholar
Limmer M, Sonntag J, de Marées M, et al. Effects of an alkalizing or acidizing diet on high-intensity exercise performance under normoxic and hypoxic conditions in physically active adults: a randomized, crossover trial. Nutrients. 2020;12.
Google Scholar
Lopes-SilvaJPDa Silva SantosJFArtioliGG et al Sodium bicarbonate ingestion increases glycolytic contribution and improves performance during simulated taekwondo combatEur J Sport Sci201818 431 440 29355092 https://doi.org/10.1080/17461391.2018.1424942 29355092
PubMed Web of Science ®Google Scholar
StephensTJMcKennaMJCannyBJ et al Effect of sodium bicarbonate on muscle metabolism during intense endurance cyclingMed Sci Sports Exerc200234 614 621 1:CAS:528:DC%2BD38Xjt1ChsLc%3D 11932569 11932569
PubMed Web of Science ®Google Scholar
EdgeJEynonNMcKennaMJ et al Altering the rest interval during high-intensity interval training does not affect muscle or performance adaptationsExp Physiol201398 481 490 22923232 https://doi.org/10.1113/expphysiol.2012.067603 22923232
PubMed Web of Science ®Google Scholar
MaliqueoSAGOjedaÁCHBarrilaoRG et al Time to fatigue on lactate threshold and supplementation with sodium bicarbonate in middle-distance college athletesArchivos de Medicina del Deporte201835 16 22
Google Scholar
NorthgravesMJPeartDJJordanCA et al Effect of lactate supplementation and sodium bicarbonate on 40-km cycling time trial performanceJ Strength Cond Res201428 273 280 23660571 https://doi.org/10.1519/JSC.0b013e3182986a4c 23660571
PubMed Web of Science ®Google Scholar
Krustrup P, Ermidis G, Mohr M. Sodium bicarbonate intake improves high-intensity intermittent exercise performance in trained young men. J Int Soc Sport Nutr. 2015;12.
Google Scholar
da SilvaRPde OliveiraLFSaundersB et al Effects of β-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exerciseAmino Acids201951 83 96 30182286 https://doi.org/10.1007/s00726-018-2643-2 1:CAS:528:DC%2BC1cXhs1Gks73O 30182286
PubMedGoogle Scholar
McGinleyCBishopDJInfluence of training intensity on adaptations in acid/base transport proteins, muscle buffer capacity, and repeated-sprint ability in active menJ Appl Physiol2016121 1290 1305 1:CAS:528:DC%2BC1cXivVWitL0%3D 27742804 https://doi.org/10.1152/japplphysiol.00630.2016 27742804
PubMedGoogle Scholar
MillerPRobinsonALSparksSA et al The effects of novel ingestion of sodium bicarbonate on repeated sprint abilityJ Strength Cond Res201630 561 568 26815179 https://doi.org/10.1519/JSC.0000000000001126 26815179
PubMed Web of Science ®Google Scholar
HadzicMEcksteinMLSchugardtMThe impact of sodium bicarbonate on performance in response to exercise duration in athletes: a systematic reviewJ Sports Sci Med201918 271 281 31191097 6544001
PubMed Web of Science ®Google Scholar
PriceMMossPRanceSEffects of sodium bicarbonate ingestion on prolonged intermittent exerciseMed Sci Sports Exerc200335 1303 1308 1:CAS:528:DC%2BD3sXmtVWisLc%3D 12900682 https://doi.org/10.1249/01.MSS.0000079067.46555.3C 12900682
PubMed Web of Science ®Google Scholar
SimoneauJABouchardCHuman variation in skeletal muscle fiber-type proportion and enzyme activitiesAm J Phys1989257 E567 E572 1:CAS:528:DyaL1MXmt12kt7w%3D
PubMed Web of Science ®Google Scholar
HeikkiläMValveRLehtovirtaM et al Nutrition knowledge among young Finnish endurance athletes and their coachesInt J Sport Nutr Exerc Metab201828 522 527 29252046 https://doi.org/10.1123/ijsnem.2017-0264 29252046
PubMedGoogle Scholar
JovanovPĐorđićVObradovićB et al Prevalence, knowledge and attitudes towards using sports supplements among young athletesJ Int Soc Sports Nutr201916 27 31272457 6611041 https://doi.org/10.1186/s12970-019-0294-7
PubMedGoogle Scholar
WangXChenYLiuY et al Reporting items for systematic reviews and meta-analyses of acupuncture: the prisma for acupuncture checklistBMC Complement Altern Med201919 208 31405367 6689876 https://doi.org/10.1186/s12906-019-2624-3
PubMedGoogle Scholar
Fernández-Lázaro D, Mielgo-Ayuso J, Seco Calvo J, et al. Modulation of exercise-induced muscle damage, inflammation, and oxidative markers by curcumin supplementation in a physically active population: a systematic review. Nutrients. 2020;12.
Google Scholar
Law MS, D. Pollock, N. Letts, L. Bosch, J. Westmorland, M.: Guidelines for critical review form—quantitative studies 1998. Hamilton, ON, Canada: McMaster University; 2008(Series Editor).
Google Scholar
MeroAAHirvonenPSaarelaJ et al Effect of sodium bicarbonate and beta-alanine supplementation on maximal sprint swimmingJ Int Soc Sports Nutr201310 52 24215679 4176133 https://doi.org/10.1186/1550-2783-10-52 1:CAS:528:DC%2BC2cXislOqsbo%3D
PubMedGoogle Scholar
OliveiraLFde SallesPVNemezioK et al Chronic lactate supplementation does not improve blood buffering capacity and repeated high-intensity exerciseScand J Med Sci Sports201727 1231 1239 1:STN:280:DC%2BC2snpvFGgtw%3D%3D 27882611 https://doi.org/10.1111/sms.12792 27882611
PubMedGoogle Scholar
Correia-OliveiraCRLopes-SilvaJPBertuzziR et al Acidosis, but not alkalosis, affects anaerobic metabolism and performance in a 4-km time trialMed Sci Sports Exerc201749 1899 1910 1:CAS:528:DC%2BC2sXhtlehtLbO 28398947 https://doi.org/10.1249/MSS.0000000000001295 28398947
PubMed Web of Science ®Google Scholar
ThomasCDelfour-PeyrethonRBishopDJ et al Effects of pre-exercise alkalosis on the decrease in vo2 at the end of all-out exerciseEur J Appl Physiol2016116 85 95 1:CAS:528:DC%2BC2MXhtlyjur%2FP 26297325 https://doi.org/10.1007/s00421-015-3239-0 26297325
PubMedGoogle Scholar
ZabalaMPeinadoABCalderónFJ et al Bicarbonate ingestion has no ergogenic effect on consecutive all out sprint tests in bmx elite cyclistsEur J Appl Physiol2011111 3127 3134 1:CAS:528:DC%2BC3MXhsFSjtbfI 21465247 https://doi.org/10.1007/s00421-011-1938-8 21465247
PubMed Web of Science ®Google Scholar
PeinadoABHolgadoDLuque-CasadoA et al Effect of induced alkalosis on performance during a field-simulated bmx cycling competitionJ Sci Med Sport201922 335 341 30170952 https://doi.org/10.1016/j.jsams.2018.08.010 30170952
PubMedGoogle Scholar
JoyceSMinahanCAndersonM et al Acute and chronic loading of sodium bicarbonate in highly trained swimmersEur J Appl Physiol2012112 461 469 1:CAS:528:DC%2BC38XpslOqug%3D%3D 21584683 https://doi.org/10.1007/s00421-011-1995-z 21584683
PubMed Web of Science ®Google Scholar
De Araujo Dias GF, Eira Silva VD, Painelli VDS, et al.: (in)consistencies in responses to sodium bicarbonate supplementation: A randomised, repeated measures, counterbalanced and double-blind study. PLoS One 2015, 10.
Google Scholar
FreisTHeckstedenASuchU et al Effect of sodium bicarbonate on prolonged running performance: a randomized, double-blind, cross-over studyPLoS One201712 28797049 5552294 https://doi.org/10.1371/journal.pone.0182158 1:CAS:528:DC%2BC1cXhslOis7Y%3D
PubMedGoogle Scholar
HigginsJPThompsonSGDeeksJJ et al Measuring inconsistency in meta-analysesBmj2003327 557 560 12958120 192859 https://doi.org/10.1136/bmj.327.7414.557
PubMed Web of Science ®Google Scholar
CohenJA power primerPsychol Bull1992112 155 159 1:STN:280:DC%2BD1MvlsV2mug%3D%3D https://doi.org/10.1037/0033-2909.112.1.155
PubMed Web of Science ®Google Scholar
Mündel T: Sodium bicarbonate ingestion improves repeated high-intensity cycling performance in the heat. Temperature (Austin, Tex) 2018, 5:343–347.
Google Scholar
CarrBMWebsterMJBoydJC et al Sodium bicarbonate supplementation improves hypertrophy-type resistance exercise performanceEur J Appl Physiol2013113 743 752 1:CAS:528:DC%2BC3sXis1Kquro%3D 22941193 https://doi.org/10.1007/s00421-012-2484-8 22941193
PubMedGoogle Scholar
SaundersBSaleCHarrisRC et al Sodium bicarbonate and high-intensity-cycling capacity: variability in responsesInt J Sports Physiol Perform20149 627 632 24155093 https://doi.org/10.1123/ijspp.2013-0295 24155093
PubMed Web of Science ®Google Scholar
HobsonRMHarrisRCMartinD et al Effect of sodium bicarbonate supplementation on 2000-m rowing performanceInt J Sports Physiol Perform20149 139 144 23579002 https://doi.org/10.1123/ijspp.2013-0086 23579002
PubMed Web of Science ®Google Scholar
SieglerJCGleadall-SiddallDOSodium bicarbonate ingestion and repeated swim sprint performanceJ Strength Cond Res201024 3105 3111 20881504 https://doi.org/10.1519/JSC.0b013e3181f55eb1 20881504
PubMedGoogle Scholar
DebSKGoughLASparksSA et al Determinants of curvature constant (w') of the power duration relationship under normoxia and hypoxia: the effect of pre-exercise alkalosisEur J Appl Physiol2017117 901 912 1:CAS:528:DC%2BC2sXjvF2qs7o%3D 28280973 5388723 https://doi.org/10.1007/s00421-017-3574-4
PubMed Web of Science ®Google Scholar
SmithGIJeukendrupAEBallDThe effect of sodium acetate ingestion on the metabolic response to prolonged moderate-intensity exercise in humansInt J Sport Nutr Exerc Metab201323 357 368 1:CAS:528:DC%2BC3sXhs1SmsbjL 23296954 https://doi.org/10.1123/ijsnem.23.4.357 23296954
PubMedGoogle Scholar
MuellerSMGehrigSMFreseS et al Multiday acute sodium bicarbonate intake improves endurance capacity and reduces acidosis in menJ Int Soc Sport Nutr201310 16 1:CAS:528:DC%2BC3sXotFCksb4%3D https://doi.org/10.1186/1550-2783-10-16
Web of Science ®Google Scholar
Egger F, Meyer T, Such U, et al. Effects of sodium bicarbonate on high-intensity endurance performance in cyclists: a double-blind, randomized cross-over trial. PLoS One. 2014;9.
Google Scholar
MacutkiewiczDSunderlandCSodium bicarbonate supplementation does not improve elite women's team sport running or field hockey skill performancePhysiol Rep20186 30318837 6186818 https://doi.org/10.14814/phy2.13818 1:CAS:528:DC%2BC1cXhvFeqsLnO
PubMedGoogle Scholar
WuCLShihMCYangCC et al Sodium bicarbonate supplementation prevents skilled tennis performance decline after a simulated matchJ Int Soc Sport Nutr20107 33 https://doi.org/10.1186/1550-2783-7-33 1:CAS:528:DC%2BC3cXhsVahsL3I
PubMed Web of Science ®Google Scholar
McNaughtonLRSieglerJMidgleyAErgogenic effects of sodium bicarbonateCurr Sports Med Rep20087 230 236 18607226 https://doi.org/10.1249/JSR.0b013e31817ef530 18607226
PubMed Web of Science ®Google Scholar
PeartDJSieglerJCVinceRVPractical recommendations for coaches and athletes: a meta-analysis of sodium bicarbonate use for athletic performanceJ Strength Cond Res201226 1975 1983 22505127 https://doi.org/10.1519/JSC.0b013e3182576f3d 22505127
PubMed Web of Science ®Google Scholar
Lopes-SilvaJPRealeRFranchiniEAcute and chronic effect of sodium bicarbonate ingestion on Wingate test performance: a systematic review and meta-analysisJ Sports Sci201937 762 771 30319077 https://doi.org/10.1080/02640414.2018.1524739 30319077
PubMed Web of Science ®Google Scholar
Lopes-SilvaJPChooHCFranchiniE et al Isolated ingestion of caffeine and sodium bicarbonate on repeated sprint performance: a systematic review and meta-analysisJ Sci Med Sport201922 962 972 31036532 https://doi.org/10.1016/j.jsams.2019.03.007 31036532
PubMed Web of Science ®Google Scholar
GoughLARimmerSSparksSA et al Post-exercise supplementation of sodium bicarbonate improves acid base balance recovery and subsequent high-intensity boxing specific performanceFront Nutr20196 155 31632978 6779834 https://doi.org/10.3389/fnut.2019.00155 1:CAS:528:DC%2BB3cXitVKrurfN
PubMed Web of Science ®Google Scholar
Durkalec-MichalskiKNowaczykPMAdrianJ et al The influence of progressive-chronic and acute sodium bicarbonate supplementation on anaerobic power and specific performance in team sports: a randomized, double-blind, placebo-controlled crossover studyNutrition & Metabolism202017 1 15 https://doi.org/10.1186/s12986-020-00457-9 1:CAS:528:DC%2BB3cXhtVeltL%2FM
Web of Science ®Google Scholar
Edge J, Bishop D, and Goodman C: Effects of chronic nahco3 ingestion during interval training on changes to muscle buffer capacity, metabolism, and short-term endurance performance. J Appl Physiol (1985) 2006, 101:918–25.
Google Scholar
KahleLEKellyPVEliotKA et al Acute sodium bicarbonate loading has negligible effects on resting and exercise blood pressure but causes gastrointestinal distressNutr Res201333 479 486 1:CAS:528:DC%2BC3sXot1Clu7o%3D 23746564 3680785 https://doi.org/10.1016/j.nutres.2013.04.009
PubMed Web of Science ®Google Scholar
SieglerJCMarshallPWBrayJ et al Sodium bicarbonate supplementation and ingestion timing: does it matter?J Strength Cond Res201226 1953 1958 21964428 https://doi.org/10.1519/JSC.0b013e3182392960 21964428
PubMedGoogle Scholar
De FrancaEXavierAPDiasIR et al Fractionated sodium bicarbonate coingestion with carbohydrate increase performance without gastrointestinal discomfortRbne20159 437 446
Google Scholar
HiltonNPLeachNKCraigMM et al Enteric-coated sodium bicarbonate attenuates gastrointestinal side-effectsInternational Journal of Sport Nutrition & Exercise Metabolism202030 62 68 1:CAS:528:DC%2BB3cXhtFeqsrrK https://doi.org/10.1123/ijsnem.2019-0151
Web of Science ®Google Scholar
GrgicJGarofoliniAPickeringC et al Isolated effects of caffeine and sodium bicarbonate ingestion on performance in the yo-yo test: a systematic review and meta-analysisJ Sci Med Sport202023 41 47 31466868 https://doi.org/10.1016/j.jsams.2019.08.016 31466868
PubMedGoogle Scholar
Ferreira LHB, Smolarek AC, Chilibeck PD, et al.: High doses of sodium bicarbonate increase lactate levels and delay exhaustion in a cycling performance test. Nutrition (Burbank, Los Angeles County, Calif) 2019, 60:94–99.
Google Scholar

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