390
Views
27
CrossRef citations to date
0
Altmetric
Original Articles

SNX-2112, a Novel Hsp90 Inhibitor, Induces G2/M Cell Cycle Arrest and Apoptosis in MCF-7 Cells

, , , , , , , , , , , & show all
Pages 1540-1545 | Received 22 Mar 2011, Accepted 10 May 2011, Published online: 22 May 2014

  • 1) Pearl LH and Prodromou C, Annu. Rev. Biochem., 75, 271–294 (2006).
  • 2) Pearl LH, Prodromou C, and Workman P, Biochem. J., 410, 439–453 (2008).
  • 3) Zhao R, Davey M, Hsu YC, Kaplanek P, Tong A, Parsons AB, Krogan N, Cagney G, Mai D, Greenblatt J, Boone C, Emili A, and Houry WA, Cell, 120, 715–727 (2005).
  • 4) Porter JR, Fritz CC, and Depew KM, Curr. Opin. Chem. Biol., 14, 412–420 (2010).
  • 5) Whitesell L and Lindquist SL, Nat. Rev. Cancer, 5, 761–772 (2005).
  • 6) Cysyk RL, Parker RJ, Barchi JJJr, Steeg PS, Hartman NR, and Strong JM, Chem. Res. Toxicol., 19, 376–381 (2006).
  • 7) Jin L, Xiao CL, Lu CH, Xia M, Xing GW, Xiong S, Liu QY, Liu H, Li YC, Ge F, Wang QD, He QY, and Wang YF, FEBS Lett., 583, 1859–1866 (2009).
  • 8) Steed PM, Fadden P, and Hall S, Am. Soc. Clin. Oncol., 24, 13067 (2006).
  • 9) Chandarlapaty S, Sawai A, Ye Q, Scott A, Silinski M, Huang K, Fadden P, Partdrige J, Hall S, Steed P, Norton L, Rosen N, and Solit DB, Clin. Cancer Res., 14, 240–248 (2008).
  • 10) Zhai QQ, Gong GQ, Liu Z, Luo Y, Xia M, Xing GW, You XF, and Wang YF, Biomed. Pharmacother., 65, 132–136 (2010).
  • 11) Zhai QQ, Gong GQ, Luo Y, Wang QD, Xia M, Xing GW, Li YC, Jiang JH, Liu Z, Liu QY, and Wang YF, J. Pharm. Biomed. Anal., 53, 1048–1052 (2010).
  • 12) Rice JW, Veal JM, Barabasz A, Foley B, Fadden P, Scott A, Huang K, Steed P, and Hall S, Oncol. Res., 18, 229–242 (2009).
  • 13) Barta TE, Veal JM, Rice JW, Partridge JM, Fadden RP, Ma W, Jenks M, Geng L, Hanson GJ, Huang KH, Barabasz AF, Foley BE, Otto J, and Hall SE, Bioorg. Med. Chem. Lett., 18, 3517–3521 (2008).
  • 14) Mosmann T, J. Immunol. Methods, 65, 55–63 (1983).
  • 15) Yang YP, Kuo HS, Tsai HD, Peng YC, and Lin YL, Breast Cancer Res., 7, R19–R27 (2005).
  • 16) Wuerzberger SM, Pink JJ, Planchon SM, Byers KL, Bornmann WG, and Boothman DA, Cancer Res., 58, 1876–1885 (1998).
  • 17) Jemal A, Siegel R, Ward E, Hao Y, Xu J, and Thun MJ, CA Cancer J. Clin., 59, 225–249 (2009).
  • 18) Konecny G, Untch M, Slamon D, Beryt M, Kahlert S, Felber M, Langer E, Lude S, Hepp H, and Pegram M, Breast Cancer Res. Treat., 67, 223–233 (2001).
  • 19) Okawa Y, Hideshima T, Steed P, Vallet S, Hall S, Huang K, Rice J, Barabasz A, Foley B, Ikeda H, Raje N, Kiziltepe T, Yasui H, Enatsu S, and Anderson KC, Blood, 113, 846–855 (2009).
  • 20) Senju M, Sueoka N, Sato A, Iwanaga K, Sakao Y, Tomimitsu S, Tominaga M, Irie K, Hayashi S, and Sueoka E, J. Cancer Res. Clin. Oncol., 132, 150–158 (2006).
  • 21) Jeffy BD, Chen EJ, Gudas JM, and Romagnolo DF, Neoplasia, 2, 460–470 (2000).
  • 22) Yin HJ, Cheng LS, and Duan JL, Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 23, 260–263 (2007).
  • 23) Tsujimoto Y, J. Cell. Physiol., 195, 158–167 (2003).
  • 24) Hetz C, Adv. Exp. Med. Biol., 687, 7–8 (2010).
  • 25) Bull EE, Dote H, Brady KJ, Burgan WE, Carter DJ, Cerra MA, Oswald KA, Hollingshead MG, Camphausen K, and Tofilon PJ, Clin. Cancer Res., 10, 8077–8084 (2004).
  • 26) Radanyi C, Le Bras G, Marsaud V, Peyrat JF, Messaoudi S, Catelli MG, Brion JD, Alami M, and Renoir JM, Cancer Lett., 274, 88–94 (2009).
  • 27) Chiosis G, Timaul MN, Lucas B, Munster PN, Zheng FF, Sepp-Lorenzino L, and Rosen N, Chem. Biol., 8, 289–299 (2001).
  • 28) Kumar R, Mandal M, Lipton A, Harvey H, and Thompson CB, Clin. Cancer Res., 2, 1215–1219 (1996).
  • 29) Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, and McGuire WL, Science, 235, 177–182 (1987).
  • 30) Kumar N, Afeyan R, Kim HD, and Lauffenburger DA, Mol. Pharmacol., 73, 1668–1678 (2008).
  • 31) Page C, Lin HJ, Jin Y, Castle VP, Nunez G, Huang M, and Lin J, Anticancer Res., 20, 407–416 (2000).
  • 32) Cheng JQ, Lindsley CW, Cheng GZ, Yang H, and Nicosia SV, Oncogene, 24, 7482–7492 (2005).
  • 33) Park K, Choi K, Kim H, Kim K, Lee MH, Lee JH, and Kim Rim JC, Exp. Mol. Med., 41, 371–381 (2009).
  • 34) Davis JM, Navolanic PM, Weinstein-Oppenheimer CR, Steelman LS, Hu W, Konopleva M, Blagosklonny MV, and McCubrey JA, Clin. Cancer Res., 9, 1161–1170 (2003).
  • 35) Kobzdej M, Matuszyk J, and Strzadala L, Leuk. Res., 24, 33–38 (2000).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.