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Bioscience, Biotechnology, and Biochemistry Volume 71, 2007 - Issue 2
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Original Articles

Highly Sensitive Quantitative Analysis of Nicotianamine Using LC/ESI-TOF-MS with an Internal Standard

Yasuaki WADAGraduate School of Agricultural and Life Sciences, The University of Tokyo
,
Isomaro YAMAGUCHIFaculty of Technology, Maebashi Institute of Technology
,
Michiko TAKAHASHIGraduate School of Agricultural and Life Sciences, The University of Tokyo
,
Hiromi NAKANISHIGraduate School of Agricultural and Life Sciences, The University of Tokyo
,
Satoshi MORIGraduate School of Agricultural and Life Sciences, The University of Tokyo
&
Naoko K. NISHIZAWAGraduate School of Agricultural and Life Sciences, The University of Tokyo;Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Corporation (JST)
Pages 435-441 | Received 12 Sep 2006, Accepted 17 Oct 2006, Published online: 22 May 2014

  • 1) Noma, M., Noguchi, M., and Tamaki, E., A new amino acid, nicotianamine, from tobacco leaves. Tetrahedron Lett., 22, 2017–2020 (1971).
  • 2) Noma, M., and Noguchi, M., Occurrence of nicotianamine in higher plants. Phytochemistry, 15, 1701–1702 (1976).
  • 3) Rudolph, A., Becker, R., Scholz, G., Prochazka, Z., Toman, J., Macel, T., and Herout, V., The occurrence of the amino acid nicotianamine in plants and microorganisms: a re-investigation. Biochem. Physiol. Pflanzen., 180, 557–563 (1985).
  • 4) von, Wiren, N., Klair, S., Bansal, S., Briat, J. F., Khodr, H., Shioiri, T., Leigh, R. A., and Hider, R. C., Nicotianamine chelates both FeIII and FeII. Implications for metal transport in plants. Plant Physiol., 119, 1107–1114 (1999).
  • 5) Takahashi, M., Terada, Y., Nakai, I., Nakanishi, H., Yoshimura, E., Mori, S., and Nishizawa, N. K., Role of nicotianamine in the intracellular delivery of metals and plant reproductive development. Plant Cell, 15, 1263–1280 (2003).
  • 6) Takagi, S., Naturally occurring iron-chelating compounds in oat- and rice-root washing. I. Activity measurement and preliminary characterization. Soil Sci. Plant Nutr., 22, 423–433 (1976).
  • 7) Mori, S., and Nishizawa, N. K., Methionine as a dominant precursor of phytosiderophores in Gramineae plants. Plant Cell Physiol., 28, 1081–1092 (1987).
  • 8) Shojima, S., Nishizawa, N. K., Fushiya, S., Nozoe, S., Irifune, T., and Mori, S., Biosynthesis of phytosiderophores. Plant Physiol., 93, 1497–1503 (1990).
  • 9) Kinoshita, E., Yamakoshi, J., and Kikuchi, M., Purification and identification of an angiotensin I-converting enzyme inhibitor from soy sauce. Biosci. Biotechnol. Biochem., 57, 1107–1110 (1993).
  • 10) Shimizu, E., Hayashi, A., Takahashi, R., Aoyagi, Y., Murakami, T., and Kimoto, K., Effects of angiotensin I-converting enzyme inhibitor from Ashitaba (Angelica keiskei) on blood pressure of spontaneously hypertensive rats. J. Nutr. Sci. Vitaminol., 45, 375–383 (1999).
  • 11) Kataoka, S., Functional effects of Japanese style fermented soy sauce (shoyu) and its components. J. Biosci. Bioeng., 100, 227–234 (2005).
  • 12) Aoyagi, Y., An angiotensin-I converting enzyme inhibitor from buckwheat (Fagopyrum esculentum Moench) flour. Phytochemistry, 67, 618–621 (2006).
  • 13) Shojima, S., Nishizawa, N. K., Fushiya, S., Nozoe, S., Kumashiro, T., Nagata, T., Ohata, T., and Mori, S., Biosynthesis of nicotianamine in the suspension-cultured cells of tobacco (Nicotiana megalosiphon). Biol. Metals, 2, 142–145 (1989).
  • 14) Higuchi, K., Suzuki, K., Nakanishi, H., Yamaguchi, H., Nishizawa, N. K., and Mori, S., Cloning of nicotianamine synthase genes, novel genes involved in the biosynthesis of phytosiderophores. Plant Physiol., 119, 471–479 (1999).
  • 15) Higuchi, K., Watanabe, S., Takahashi, M., Kawasaki, S., Nakanishi, H., Nishizawa, N. K., and Mori, S., Nicotianamine synthase gene expression differs in barley and rice under Fe-deficient conditions. Plant J., 25, 159–167 (2001).
  • 16) Suzuki, K., Higuchi, K., Nakanishi, H., Nishizawa, N. K., and Mori, S., Cloning of nicotianamine synthase gene from Arabidopsis. Soil Sci. Plant Nutr., 45, 993–1002 (1999).
  • 17) Mizuno, D., Higuchi, K., Sakamoto, T., Nakanishi, H., Mori, S., and Nishizawa, N. K., Three nicotianamine synthase genes isolated from maize are differentially regulated by iron nutritional status. Plant Physiol., 132, 1989–1997 (2003).
  • 18) Mori, S., and Nishizawa, N. K., Methionine as a dominant precursor of phytosiderophores in Gramineae plants. Plant Cell Physiol., 28, 1081–1092 (1987).
  • 19) Shojima, S., Nishizawa, N. K., and Mori, S., Establishment of cell-free system for the biosynthesis of nicotinamine. Plant Cell Physiol., 30, 673–677 (1989).
  • 20) Wada, Y., Kobayashi, T., Takahashi, M., Nakanishi, H., Mori, S., and Nishizawa, N. K., Metabolic engineering of Saccharomyces cerevisiae producing nicotianamine: Potential for industrial biosynthesis of a novel antihypertensive substrate. Biosci. Biotechnol. Biochem., 70, 1408–1415 (2006).
  • 21) Kim, S., Takahashi, M., Higuchi, K., Tsunoda, K., Nakanishi, H., Yoshimura, E., Mori, S., and Nishizawa, N. K., Increased Nicotianamine biosynthesis confers enhanced tolerance of high levels of metals, in particular nickel, to plants. Plant Cell Physiol., 46, 1809–1818 (2005).
  • 22) Weber, M., Harada, E., Vess, C., Roepenack-Lahaye, E., and Clemens, S., Comparative microarray analysis of Arabidopsis thaliana and Arabidopsis halleri roots identifies nicotianamine synthase, a ZIP transporter and other genes as potential metal hyperaccumulation factors. Plant J., 37, 269–281 (2004).
  • 23) Chan, E. C. Y., Wee, P. Y., Ho, P. Y., and Ho, P. C., High-performance liquid chromatography assay for catecholamines and metanephrine using fluorimetric detection with pre-column 9-fluorenylmethoxycarboxyl chloride detection. J. Chromatogr. B, 749, 179–189 (2000).
  • 24) Kim, J. W., Kim, S. U., Lee, H. S., Kim, I., Ahn, M. Y., and Ryu, K. S., Determination of 1-deoxynojirimycin in Morus alba L. leaves by derivatization with 9-fluorenylmethyl chloroformate followed by reversed-phase high-performance liquid chromatography. J. Chromatogr. A, 1002, 93–99 (2003).
  • 25) Wheal, M. S., Heller, L. I., Norvell, W. A., and Welch, R. M., Reversed-phase liquid chromatographic determination of phytometallophores from Strategy II Fe-uptake species by 9-fluorenylmethyl chloroformate fluorescence. J. Chromatogr. A, 942, 173–183 (2002).

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