Advanced search
Publication Cover
Bioscience, Biotechnology, and Biochemistry Volume 71, 2007 - Issue 3
Journal homepage
164
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

Taurocholic Acid Does Not Induce Apoptosis in HCT116 Cells Regardless of Its Intracellular Concentration

Satoko YUILaboratory of Molecular Nutrition, Department of Biological Function, Kyoto Prefectural University
,
Ryuhei KANAMOTOLaboratory of Molecular Nutrition, Department of Biological Function, Kyoto Prefectural University
,
Kimikazu IWAMILaboratory of Molecular Nutrition, Department of Biological Function, Kyoto Prefectural University
&
Tohru SAEKILaboratory of Molecular Nutrition, Department of Biological Function, Kyoto Prefectural University
Pages 800-802 | Received 15 Sep 2006, Accepted 22 Dec 2006, Published online: 22 May 2014

  • 1) Dawson, P. A., and Oelkers, P., Bile acid transporters. Curr. Opin. Lipidol., 6, 109–114 (1995).
  • 2) Hagenbuch, B., and Meier, P. J., Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter. J. Clin. Invest., 93, 1326–1331 (1994).
  • 3) Hagenbuch, B., Stieger, B., Foguet, M., Lubbert, H., and Meier, P. J., Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system. Proc. Natl. Acad. Sci. USA, 88, 10629–10633 (1991).
  • 4) Saeki, T., Matoba, K., Furukawa, H., Kirifuji, K., Kanamoto, R., and Iwami, K., Characterization, cDNA cloning, and functional expression of mouse ileal sodium-dependent bile acid transporter. J. Biochem. (Tokyo), 125, 846–851 (1999).
  • 5) Shneider, B. L., Dawson, P. A., Christie, D. M., Hardikar, W., Wong, M. H., and Suchy, F. J., Cloning and molecular characterization of the ontogeny of a rat ileal sodium-dependent bile acid transporter. J. Clin. Invest., 95, 745–754 (1995).
  • 6) Jones, B. A., Rao, Y. P., Stravitz, R. T., and Gores, G. J., Bile salt-induced apoptosis of hepatocytes involves activation of protein kinase C. Am. J. Physiol., 272, G1109–1115 (1997).
  • 7) Marchetti, M. C., Migliorati, G., Moraca, R., Riccardi, C., Nicoletti, I., Fabiani, R., Mastrandrea, V., and Morozzi, G., Possible mechanisms involved in apoptosis of colon tumor cell lines induced by deoxycholic acid, short-chain fatty acids, and their mixtures. Nutr. Cancer, 28, 74–80 (1997).
  • 8) Reinehr, R., Graf, D., and Haussinger, D., Bile salt-induced hepatocyte apoptosis involves epidermal growth factor receptor-dependent CD95 tyrosine phosphorylation. Gastroenterology, 125, 839–853 (2003).
  • 9) Schlottman, K., Wachs, F.-P., Krieg, R. C., Kullmann, F., Scholmerich, J., and Rogler, G., Characterization of bile salt-induced apoptosis in colon cancer cell lines. Cancer Res., 60, 4270–4276 (2000).
  • 10) Sodeman, T., Bronk, S. F., Roberts, P. J., Miyoshi, H., and Gores, G. J., Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas. Am. J. Physiol. Gastrointest. Liver Physiol., 278, G992–999 (2000).
  • 11) Graf, D., Kurz, A. K., Fischer, R., Reinehr, R., and Haussinger, D., Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner. Gastroenterology, 122, 1411–1427 (2002).
  • 12) Higuchi, H., and Gores, G. J., Bile acid regulation of hepatic physiology. IV. Bile acids and death receptors. Am. J. Physiol. Gastrointest. Liver Physiol., 284, G734–G738 (2003).
  • 13) Higuchi, H., Yoon, J.-H., Grambihler, A., Werneburg, N., Bronk, S. F., and Gores, G. J., Bile acids stimulate cFLIP phosphorylation enhancing TRAIL-mediated apoptosis. J. Biol. Chem., 278, 454–461 (2003).
  • 14) Wachs, F. P., Krieg, R. C., Rodrigues, C. M., Messmann, H., Kullmann, F., Knuchel-Clarke, R., Scholmerich, J., Rogler, G., and Schlottmann, K., Bile salt-induced apoptosis in human colon cancer cell lines involves the mitochondrial transmembrane potential but not the CD95 (Fas/Apo-1) receptor. Int. J. Colorectal. Dis., 20, 103–113 (2005).
  • 15) Yui, S., Saeki, T., Kanamoto, R., and Iwami, K., Characteristics of apoptosis in HCT116 colon cancer cells induced by deoxycholic acid. J. Biochem. (Tokyo), 138, 151–157 (2005).
  • 16) Saeki, T., Takahashi, N., Kanamoto, R., and Iwami, K., Characterization of cloned mouse Na+/taurocholate cotransporting polypeptide by transient expression in COS-7 cells. Biosci. Biotechnol. Biochem., 66, 1116–1118 (2002).
  • 17) Roda, A., Minutello, A., Angellotti, M. A., and Fini, A., Bile acid structure-activity relationship: evaluation of bile acid lipophilicity using 1-octanol/water partition coefficient and reverse phase HPLC. J. Lipid Res., 31, 1433–1443 (1990).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.