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Bioscience, Biotechnology, and Biochemistry Volume 62, 1998 - Issue 10
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Original Articles

A Common Phosphorylation Site for Cyclic AMP-dependent Protein Kinase and Protein Kinase C in Human Placental 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase

Noriko OKAMURADepartment of Clinical Pharmaceutics, Graduate School of Pharmaceutical Sciences, Nagasaki University
&
Ryuzo SAKAKIBARADepartment of Clinical Pharmaceutics, Graduate School of Pharmaceutical Sciences, Nagasaki University
Pages 2039-2042 | Received 30 Apr 1998, Published online: 22 May 2014

  • . 1991. p. 445- 456.
  • 2) Rousseau, G. G. and Hue, L., Mammalian 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: A bifunctional enzyme that controls glycolysis. Prog. Nucleic Acid Res. Mol. Biol., 45, 99-127 (1993).
  • 3) Pilkis, S. J., Claus, T. H., Kurland, I. J., and Lange, A. J., 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: A metabolic signaling enzyme. Annu. Rev. Biochem., 64, 799-835 (1995).
  • 4) Furuya, E., Yokoyama, M., and Uyeda, K., Regulation of fructose-6-phosphate,2-kinase by phosphorylation and dephosphorylation: Possible mechanism for coordinated control of glycolysis and glycogenolysis. Proc. Natl. Acad. Sci. U.S.A., 79, 325-329 (1982).
  • 5) El-Maghrabi, M. R., Claus, T. H., Pilkis, J., and Pilkis, S. J., Regulation of 6-phosphofructo-2-kinase activity by cyclic AMP-dependent phosphorylation. Proc. Natl. Acad. Sci. U.S.A., 79, 315-319 (1982).
  • 6) van Schaftingen, E., Davies, D. R., and Hers, H. G., Inactivation of phosphofructokinase 2 by cyclic AMP-dependent protein kinase. Biochem. Biophys. Res. Commun., 103, 362-368 (1981).
  • 7) Sakakibara, R., Kitajima, S., and Uyeda, K., Differences in kinetic properties of phospho and dephospho forms of fructose-6-phosphate,2-kinase and fructose 2,6-bisphosphatase., J. Biol. Chem., 259, 41-49 (1984).
  • 8) Crepin, K. M., De Cloedt, M., Vertommen, D., Foret, D., Michel, A., Rider, M. H., Rousseau, G. G., and Hue, L., Molecular forms of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase expressed in rat skeletal muscle., J. Biol. Chem., 267, 21698-21704 (1992).
  • 9) Kitamura, K., Uyeda, K., Kangawa, K., and Matsuo, H., Purification and characterization of rat skeletal muscle fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase. J. Biol. Chem., 264, 9799-9806 (1989).
  • 10) Kitamura, K. and Uyeda, K., The mechanism of activation of heart fructose 6-phosphate,2-kinase:fructose-2,6-bisphosphatase. J. Biol. Chem., 262, 679-681 (1987).
  • 11) Kitamura, K., Kangawa, K., Matsuo, H., and Uyeda, K., Phosphorylation of myocardial fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase by cAMP-dependent protein kinase and protein kinase C. Activation by phosphorylation and amino acid sequences of the phosphorylation sites. J. Biol. Chem., 263, 16796-16801 (1988).
  • 12) Sakata, J. and Uyeda, K., Bovine heart fructose-6-phosphate 2-kinase/fructose-2,6-bisphosphatase: Complete amino acid sequence and localization of phosphorylation sites. Proc. Natl. Acad. Sci. U.S.A., 87, 4951-4955 (1990).
  • 13) Sakai, A., Kato, M., Fukasawa, M., Ishiguro, M., Furuya, E., and Sakakibara, R., Cloning of cDNA encoding for a novel isozyme of fructose 6-phosphate,2-kinase/fructose 2,6-bisphosphatase from human placenta. J. Biochem., 119, 506-511 (1996).
  • 14) Sakakibara, R., Kato, M., Okamura, N., Nakagawa, T., Komada, Y., Tominaga, N., Shimojo, M., and Fukasawa, M., Characterization of a human placental fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. J. Biochem., 122, 122-128 (1997).
  • 15) Tominaga, N., Minami, Y., Sakakibara, R., and Uyeda, K., Significance of the amino terminus of rat testis fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase. J. Biol. Chem., 268, 15951-15957 (1993).
  • 16) Laemmli, U. K., Cleavage of structural proteins during the assembly of head bacteriophage T4. Nature, 227, 680-685 (1970).
  • 17) Bradford, M. M., A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254 (1976).
  • 18) Woodgett, J. R., Gould, K. L., and Hunter, T., Substrate specificity of protein kinase C. Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements. Eur. J. Biochem., 161, 177-184 (1986).
  • 19) Rider, M. H., Damme, J. V., Vertommen, D., Michel, A., Vandekerckhove, J., and Hue, L., Evidence for new phosphorylation sites for protein kinase C and cyclic AMP-dependent protein kinase in bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. FEBS Letters, 310, 139-142 (1992).

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