- 1) Steller, H., Mechanisms and genes of cellular suicide. Science, 267, 1445-1449 (1995).
- 2) Martin, S. J., and Green, D. R., Protease activation during apoptosis: Death by a thousand cuts? Cell, 82, 349-352 (1995).
- 3) Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C., Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature, 371, 346-347 (1994).
- 4) Shiokawa, D., Maruta, H., and Tanuma, S., Inhibitors of poly(ADP-ribose) polymerase suppress nuclear fragmentation and apoptotic-body formation during apoptosis in HL-60 cells. FEBS Lett., 413, 99-103 (1997).
- 5) Kuo, M.-L., Chau, Y.-P., Wang, J.-H., and Shiah, S.-G., Inhibitors of poly(ADP-ribose) polymerase block nitric oxide-induced apoptosis but not differentiation in human leukemia HL-60 cells. Biochem. Biophys. Res. Commun., 219, 502-508 (1996).
- 6) Nosseri, C., Coppola, S., and Ghibelli, L., Possible involvement of poly(ADP-ribosyl) polymerase in triggering stress-induced apoptosis. Exp. Cell Res., 212, 367-373 (1994).
- . 1989.
- . 1992.
- 9) Wang, Z.-Q., Auer, B., Sting, L., Berghammer, H., Haidacher, D., Schweiger, M., and Wagner, E. F., Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes Dev., 9, 509-520 (1995).
- 10) Wang, Z.-Q., Sting, L., Morrison, C., Jantsch, M., Los, M., Schulze-Ostchoff, K., and Wanger, E. F., PARP is important for genomic stability but dispensable in apoptosis. Genes Dev., 11, 2347-2358 (1997).
- 11) de Murcia, J. M., Niedergang, C., Trucco, C., Ricoul, M., Dutrillaux, B., Mark, M., Oliver, F. J., Masson, M., Dierich, A., LeMeur, M., Walztinger, C., Chambon, P., and de Murcia, G., Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc. Natl. Acad. Sci. USA, 94, 7303-7307 (1997).
- 12) Svedmyr, N., Harthon, L., and Lundholm, L., The relationship between the plasma concentration of free nicotinic acid and some of its pharmacologic effects in man. Clin. Pharmacol. Ther., 10, 559-570 (1969).
- 13) Dulin, W. E., and Wyse, M., Reversal of streptozotocin diabetes with nicotinamide. Proc. Soc. Exp. Biol. Med., 130, 992-994 (1969).
- 14) Ogata, S., Okumura, K., and Taguchi, H., The effects of niacin on DNA repair after N-methyl-N′-nitro-N-nitrosoguanidine treatment in normal human lymphocytes. Biosci. Biotechnol. Biochem., 61, 2116-2118 (1997).
- 15) Nicoletti, I., Migliorati, G., Pagliacci, M. C., Grignani, F., and Riccardi, C., A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods, 139, 271-279 (1991).
- 16) Evans, G. W., and Johnson, E. C., Growth stimulating effect of picolinic acid added to rat diets. Proc. Soc. Exp. Biol. Med., 165, 457-461 (1980).
- 17) Warth, A. D., Determination of dipicolinic acid in bacterial spores by derivative spectroscopy, Anal. Biochem., 130, 502-505 (1983).
- 18) Kristen, S. K., Sherril, L. G., and P. Richard, V., Iron deprivation inhibits cyclin-dependent kinase activity and decrease cyclin D/CDK4 protein levels in asynchronous MDA-MB-453 human breast cancer cells. Exp. Cell Res., 229, 60-68 (1996).
- 19) Fukuchi, K., Tomoyasu, S., Tsuruoka, N., and Gomi, K., Iron deprivation-induced apoptosis in HL-60 cells. FEBS Lett., 350, 139-142 (1994).
- 20) Frenandez-Pol, J. A., Bono, V. H., and Johnson, G. E., Control of growth by picolinic acid: differential response of normal and transformed cells. Proc. Natl. Acad. Sci. USA, 74, 2889-2893 (1977).
- 21) Lynn, D. G., Nakanishi, K., Patt, S. L., Occolowitz, J. L., Almeida, S., and Evans, L. S., Isolation and characterization of first mitotic cycle hormone that regulates cell proliferation. J. Am. Chem. Soc., 100, 7759-7760 (1978).
- 22) Ueda, K. and Banasik, M., Inhibitors and activators of ADP-ribosylation reactions. Mol. Cell. Biochem., 138, 185-197 (1994).
- 23) Perkins, M. N., and Stone, T. W., An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res., 247, 184-187 (1982).
- 24) Kawashima, T., Sanaka, T., Sugino, N., Takahashi, M., and Mizoguchi, H., Suppressive effect of quinolinic acid and hippuric acid on bone marrow erythroid growth and lymphocyte blast formation in uremia. Adv. Exp. Med. Biol., 223, 69-72 (1987).
- 25) Hoshino, J., Kühne, U., and Kröger, H., Enhancement of DNA synthesis and cell proliferation by 1-methylnicotinamide in rat liver cells in culture. Biochem. Biophys. Res. Commun., 105, 1446-1452 (1982).
- 26) Enari, M., Talanian, R. V., Wong, W. W., and Nagata, S., Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature, 380, 723-726 (1996).
- 27) Boldin, M. P., Goncharov, T. M., Goltsev, Y. V., and Wallach, D., Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell, 85, 803-815 (1996).
- 28) Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O’Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., and Dixit, V. M., FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell, 85, 817-827 (1996).
- 29) Faleiro, L., Kobayashi, R., Fearnhead, H., and Lazebnik, Y., Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells. EMBO J., 16, 2271-2281 (1997).
- 30) Polverino, A. J., and Patterson, S. D., Selective activation of caspases during apoptotic induction in HL-60 cells. Effects of a tetrapeptide inhibitor. J. Biol. Chem., 272, 7013-7021 (1997).
Full access
Apoptosis Induced by Niacin-related Compounds in HL-60 Cells
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.