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Bioscience, Biotechnology, and Biochemistry Volume 64, 2000 - Issue 6
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Original Articles

Application of a Single-cell Gel Electrophoresis (Comet) Assay to Screen the Antimutagenic Activity in Foods

Misao MIWANational Food Research Institute, Ministry of Agriculture, Forestry and Fisheries
&
Yasuhisa HONGONational Food Research Institute, Ministry of Agriculture, Forestry and Fisheries
Pages 1292-1294 | Received 22 Nov 1999, Accepted 21 Jan 2000, Published online: 22 May 2014

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  • 4) Yendle, J. E., Tinwell, H., Elliot, B. M., and Ashby, J., The genetic toxicity of time: Importance of DNA-unwinding time to the outcome of single-cell gel electrophoresis assays. Mutation Res., 375, 125-136 (1997).
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  • 6b) Plewa, M. J., Wagner, E. D., Berhow, M. A., Conway, A., Rayburn, A. L., and Anderson, D., Antimutagenic activity of chemical fraction isolated from commercial soybean processing by-product. Teratogenesis Carcinog Mutagen., 19, 121-135 (1999).
  • 7) Kasai, H., Yamaizumi, Z., Shiomi, T., Yokoyama, S., Miyazawa, T., Wakabayashi, K., Nagao, M., Sugimura, T., and Nishimura, S., Structure of a potent mutagen isolated from fried beef. Chem. Lett., 485-488 (1981).
  • 8a) Stavric, B., Antimutagens and anticarcinogens in foods. Food Chem. Toxic., 32, 79 (1994).
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  • 11) Arimoto, S., Inhibitory effect of biological porphyrins on the mutagenicity of polycyclic compounds. Environmental Mutagen Res. Com., 12, 23-34 (1990).

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