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Original Articles

Effects of Germinated Barley Foodstuff on Microflora and Short Chain Fatty Acid Production in Dextran Sulfate Sodium-induced Colitis in Rats.

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Pages 1794-1800 | Received 28 Sep 1999, Accepted 17 May 2000, Published online: 22 May 2014

  • 1) Roediger, W. E. W., Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut, 21, 793-798 (1980).
  • 2) Hond, E. D., Hiele. M., Evenepoel, P., Peeters, M., Ghoos, Y., and Rutgeerts, P., In vivo butyrate metabolism and colonic permeability in extensive colitis. Gastroenterology, 115, 548-590 (1998).
  • 3) Kanauchi, O., Nakamura, T., Agata, K., Mitsuyama, K., and Iwanaga, T., Effects of germinated barley foodstuff on dextran sulfate sodium-induced colitis in rats. J. Gastroenterol., 33, 179-188 (1998).
  • 4) Elson, C. O., Sartor, R. B., Tennyson, G. S., Riddell, R. H., Experimental models of inflammatory bowel disease. Gastroenterology, 109, 1344-1367 (1995).
  • 5) Mitsuyama, K., Saiki, T., Kanauchi, O., Iwanaga, T., Tomiyasu, N., Nishiyama, T., Tateishi, H., Shirachi, A., Ide, M., Suzuki, A., Noguchi, K., Ikeda, H., Toyonaga, A., and Sata, M., Treatment of ulcerative colitis with germinated barley foodstuff feeding: a pilot study. Aliment. Pharmacol. Ther., 12, 1225-1230 (1998).
  • 6) Pattee, P. L., and Thompson, W. G., Drug treatment of the irritable bowel syndrome. Drugs, 44, 200-206 (1992).
  • 7) Cummings, J. H., Hill, M. J., and Jenkins, D. J. A., Changes in fecal composition and colonic function due to cereal fiber. Am. J. Clin. Nutr., 29, 1473-1486 (1976).
  • 8) Kanauchi, O., Agata, K., Protein, and dietary fiber-rich new foodstuff from brewer’s spent grain increased excretion of feces and jejunum mucosal protein content in rats. Biosci. Biotechnol. Biochem., 61, 449-454 (1997).
  • 9) Kanauchi, O., Nakamura, T., Agata, K., Fushiki, T., Preventive effect of germinated barley foodstuff on diarrhea induced by water-soluble dietary fiber in rats. Biosci. Biotechnol. Biochem., 61, 449-454 (1997).
  • 10) Oda, T., Role of mast cells in dextran sulfate sodium-induced experimental colitis in rats. J. Kyoto Pref. Univ. Med., 104, 1069-1082 (1995).
  • 11) Iwanaga, T., Hoshi, O., Han. H., and Fujita, T., Morphological analysis of acute ulcerative colitis experimentally induced by dextran sulfate sodium in the guinea pig: Some possible mechanisms of cecal ulceration. J. Gastroenterol., 29, 430-438 (1994).
  • 12) TOSOH Separation Report, No. 076 and No. 080.
  • 13) Ichikawa, H., and Sakata, T., Effect of L-lactic acid, short - chain fatty acids, and pH in cecal infusate on morphometric and cell kinetic parameters of rat cecum. Dig. Dis. Sci., 42, 1598-1610 (1997).
  • 14) Campbell, J. M., Fahey, Jr. G. C., and Wolf, B. W., Selected indigestible oligosaccharides affect large bowel mass, cecal and fecal short-chain fatty acids, pH and microflora in rats. J. Nutr., 127, 130-136 (1997).
  • . 1984. p. 53- 119.
  • 16) Kanauchi, O., Hitomi, Y., and Agata, K., Germinated barley foodstuff improves constipation induced by loperamide in rats. Biosci. Biotechnol. Biochem., 62, 1788-1790 (1998).
  • . 1996. p. 87- 97.
  • 18) Wang, J., and Friedman, E. A., Short-chain fatty acids induce cell cycle inhibitors in colonocytes. Gastroenterology, 114, 940-946 (1998).
  • 19) Kanauchi, O., Fujiyama, Y., Mitsuyama, K., Araki, Y., Ishii, T., Nakamura, T., Hitomi, Y., Agata, K., Saiki, T., Andoh, A., Toyonaga, A., and Bamba, T., Increased growth of Bifidobacterium and Eubacterium by germinated barley foodstuff, accompanied by enhanced butyrate production in healthy volunteers. Int J Mol Med, 3, 175-179 (1999).
  • 20) Kanauchi, O., Mitsuyama, K., Saiki, T., Fushiki, T., and Iwanaga, T., Germinated barley foodstuff increases fecal volume and butyrate production in humans. Int J Mol Med, 1, 937-941 (1998).
  • 21) Okayasu, I., Hatakeyama, S., Yamada, M., Ohkusa, T., Inagaki, Y., Nakaya, R., A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology, 98, 694-702 (1990).
  • 22) Kobayashi, K., Asakura, H., Hamada, Y., Hibi, T., Watanabe, M., Yoshida, T., Watanabe, N., Miura, S., Aiso, S., and Tsuchiya, M., T lymphocyte subpopulations and immunoglobulin-containing cells in the colonic mucosa of ulcerative colitis; A morphometric and immunohistochemical study. J. Clin. Lab. Immunol., 25, 63-8 (1988).
  • 23) Abraham, R., Fabian, R. J., Golberg, L., and Coulston, F., Role of lysosomes in carrageenan-induced cecal ulceratation. Gastroenterology, 67, 1169-81 (1976).
  • 24) Watt, J., Marcus, R., Experimental ulcerative disease of the colon. Methods Achiev Exp. Pathol., 7, 56-71 (1975).
  • 25) Iwanaga, T., Hoshi, O., Han, H., and Fujita, T., Morphological analysis of acute ulcerative colitis experimentally induced by dextran sulfate sodium in the guinea pig: Some possible mechanisms of cecal ulceration. J. Gastroenterol., 29, 430-8 (1994).
  • 26) Onderdonk, A. B., Hermos, J. A., Bartlett, J. G., The role of the intestinal microflora in experimental colitis. Am. J. Clin. Nutr., 30, 1819-25 (1977).
  • 27) Bañares, F.F., Hinojosa, J., Lombraña, L. S., Navarro, E., Salmeron, J. F. M., Puges, A. G., Huix, F. G., Riera, J., Lara, V. G., Abascal, F. D., Gine, J. J., Moles, J., Gomollon, F., and Gassull, M. A., Randomized clinical trial of Plantago ovata seeds (dietary fiber) as compared with mesalamine in maintaining remission in ulcerative colitis. Am. J. Gastroenterol., 94, 427-433 (1999).
  • 28) Ishikawa, F., Takayama, H., Matsumoto, K., Effect of β 1-4 linked galactooligosaccharides on human fecal microflora. Bifidus, 9, 5-18 (1995).
  • 29) Gibson, G. R., and Roberfroid, M. B., Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J. Nutr., 125, 1401-1412 (1995).
  • 30) Kanauchi, O., Agata, K., Fushiki, T., Mechanism for the increased defecation and jejunum mucosal protein content in rats by feeding germinated barley foodstuff. Biosci. Biotechnol. Biochem., 61, 443-448 (1997).
  • 31) Windmueller, H. G., Spaeth, A. E., Identification of ketone bodies and glutamine as the major respiratory fuels in vivo for postabsorptive rat small intestine. J. Biol. Chem., 253, 69-76 (1978).
  • 32) Roediger, W. E. W., The colonic epithelium in ulcerative colitis: An energy-deficient disease? Lancet, 2, 712-715 (1980).
  • 33) Lupton, J. R., Morin, J., Robinson, M. C., Barley bran flour accelerates gastrointestinal transit time. J. Am. Diet. Assoc., 93, 881-885 (1993).
  • 34) Lupton, J. R., Robinson, M. C., Morin, J., Cholesterol-lowering effect of barley bran flour and oil. J. Am. Diet. Assoc., 94, 65-70 (1994).
  • 35) Reeves, P. G., Nielson, F. H., Fahey, G. C., AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc Writing Committee on the reformulation of the AIN-76A rodent diet. J. Nutr., 123, 1939-1951 (1993).

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