- 1) Tada, S., Iimura, Y., Gomi, K., Takahashi, K., Hara, S., and Yoshizawa, K., Cloning and nucleotide sequence of the genomic Taka-amylase A gene of Aspergillus oryzae. Agric. Biol. Chem., 53, 593-599 (1989).
- 2) Hata, Y., Kitamoto, K., Gomi, K., Kumagai, C., Tamura, G., and Hara, S., The glucoamylase cDNA from Aspergillus oryzae: its cloning, nucleotide sequence, and expression in Saccharomyces cerevisiae. Agric. Biol. Chem., 55, 941-949 (1991).
- 3) Hata, Y., Tsuchiya, K., Kitamoto, K., Gomi, K., Kumagai, C., Tamura, G., and Hara, S., Nucleotide sequence and expression of the glucoamylase-encoding gene (glaA) from Aspergillus oryzae. Gene, 108, 145-150 (1990).
- 4) Minetoki, T., Gomi, K., Kitamoto, K., Kumagai, C., and Tamura, G., Nucleotide sequence and expression of α-glucosidase-encoding gene (agdA) from Aspergillus oryzae. Biosci. Biotechnol. Biochem., 59, 1516-1521 (1995).
- 5) Hata, Y., Kitamoto, K., Gomi, K., Kumagai, C., and Tamura, G., Functional elements of the promoter region of the Aspergillus oryzae glaA gene encoding glucoamylase. Curr. Genet., 22, 85-91 (1992).
- 6) Minetoki, T., Nunokawa, Y., Gomi, K., Kitamoto, K., Kumagai, C., and Tamura, G., Deletion analysis of promoter elements of the Aspergillus agdA gene encoding α-glucosidase. Curr. Genet., 30, 432-438 (1996).
- 7) Tada, S., Gomi, K., Kitamoto, K., Kumagai, C., Tamura, G., and Hara, S., Identification of the promoter region of the Taka-amylase A gene required for starch induction. Agric. Biol. Chem., 55, 1939-1941 (1991).
- 8) Tsuchiya, K., Tada, S., Gomi, K., Kitamoto, K., Kumagai, C., and Tamura, G., Deletion analysis of the Taka-amylase A gene promoter using a homologous transformation system in Aspergillus oryzae. Biosci. Biotechnol. Biochem., 56, 1849-1853 (1992).
- 9) Nagata, O., Takahashi, T., Tanaka, M., and Tsukagoshi, N., Aspergillus nidulans nuclear proteins bind to a CCAAT element and the adjacent upstream sequence in the promoter region of the starch-inducible Taka-amylase A gene. Mol. Gen. Genet., 237, 251-260 (1993).
- 10) Kato, M., Aoyama, A., Naruse, F., Kobayashi, T., and Tsukagoshi, N., An Aspergillus nidulans nuclear protein, AnCP, involved in enhancement of Taka-amylase A gene expression, binds to the CCAAT-containing taaG2, amdS, and gatA promoters. Mol. Gen. Genet., 254, 119-126 (1997).
- 11) Minetoki, T., Nunokawa, Y., Gomi, K., Kitamoto, K., and Kumagai, C., Improvement of promoter activity by the introduction of multiple copies of the conserved region III sequence, involved in the efficient expression of Aspergillus oryzae amylase-encoding genes. Appl. Microbiol. Biotechnol., 50, 459-467 (1998).
- 12) Minetoki, T., Gomi, K., Kitamoto, K., Kumagai, C., and Tamura, G., Characteristic expression of three amylase-encoding genes, agdA, amyB, and glaA in Aspergillus oryzae transformants containing multiple copies of the agdA gene. Biosci. Biotechnol. Biochem., 59, 2251-2254 (1995).
- 13) Kelly, J. M. and Hynes, M. J., Multiple copies of the amdS gene of Aspergillus nidulans cause titration of trans-acting regulatory proteins. Curr. Genet., 12, 21-31 (1987).
- 14) Andrianopoulos, A. and Hynes, M. J., Cloning and analysis of the positively acting regulatory gene amdR from Aspergillus nidulans. Mol. Cell. Biol., 8, 3532-3541 (1988).
- 15) Cove, D. J., The induction and repression of nitrate reductase in the fungus Aspergillus nidulans. Biochim. Biophys. Acta, 133, 51-56 (1966).
- 16) Gomi, K., Iimura, Y., and Hara, S., Integrative transformation of Aspergillus oryzae with a palsmid containing the Aspergillus nidulans argB gene. Agric. Biol. Chem., 51, 2549-2555 (1987).
- 17) Brakhage, A. A., Browne, P., and Turner, G., Regulation of Aspergillus nidulans penicillin biosynthesis and penicillin biosynthesis genes acvA and ipnA by glucose. J. Bacteriol., 174, 3789-3799 (1992).
- 18) van Gorcom, R. F., Punt, P. J., Pouwels, P. H., and van den Hondel, C. A. M. J. J., A system for the analysis of expression signals in Aspergillus. Gene, 48, 211-217 (1986).
- 19) Yamada, O., Lee, B. R., and Gomi, K., Transformation system for Aspergillus oryzae with double auxotrophic mutations, niaD and sC. Biosci. Biotechnol. Biochem., 61, 1367-1369 (1997).
- 20) Pontecorvo, G., Roper, J. A., Hemmoms, J. L., MacDonald, K. D., and Bufton, A. W. J., The genetics of Aspergillus nidulans. Adv. Genet., 5, 141-238 (1953).
- 21) Gems, D., Johnstone, I. L., and Clutterbuck, A. J., An autonomously replicating plasmid transforms Aspergillus nidulans at high frequency. Gene, 98, 61-67 (1991).
- 22) Ballance, D. J., Buxton, F. P., and Turner, G., Transformation of Aspergillus nidulans by the orotidine-5′-phosphate decarboxylase gene of Neurospora crassa. Biochem. Biophys. Res. Commun., 112, 284-289 (1983).
- 23) Hanahan, D., Studies on transformation of Escherichia coli with plasmids. J. Mol. Biol., 166, 557-580 (1983).
- 24) Chomczynski, P. and Sacchi, N., Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159 (1987).
- 25) Sanger, F., Nicklen, S., Coulson, A. R., DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. U.S.A., 74, 5463-5467 (1977).
- 26) Adachi, T., The new method of α-amylase assay of sake-koji (Aspergillus oryzae). J. Ferment. Technol., 32, 448-451 (1954).
- 27) Tada, S., Gomi, K., Kitamoto, K., Takahashi, K., Tamura, G., and Hara, S., Construction of a fusion gene comprising the Taka-amylase A promoter and the Escherichia coli β-glucuronidase gene and analysis of its expression in Aspergillus oryzae. Mol. Gen. Genet., 229, 301-306 (1991).
- . 1972. p. 352- 355.
- 29) Lowry, O. H., Rosebrough, N. J., and Randall, R. J., Protein measurement with the folin phenol reagent. J. Biol. Chem., 193, 265-275 (1951).
- . 1987. p. 93- 139.
- 31) Adams, T. H. and Timberlake, W., Upstream elements repress premature expression of an Aspergillus developmental regulatory gene. Mol. Cell. Biol., 10, 4912-4919 (1990).
- 32) Punt, P. J., Dingemanse, M. A., Kuyvenhoven, A., Soede, R. D., Pouwels, P. H., and van den Hondel, C. A. M. J. J., Functional elements in the promoter region of the Aspergillus nidulans gpdA gene encoding glyceraldehyde-3-phosphate dehydrogenase. Gene, 93, 101-109 (1990).
- 33) Chenchik, A., Diachenko, L., Moqadam, F., Tarabykin, V., Lukyanov, S., and Siebert, P. D., Full-length cDNA cloning and determination of mRNA 5′ and 3′ ends by amplification of adaptor-ligated cDNA. BioTechniques, 21, 526-534 (1996).
- . 1992. p. 54- 99.
- 35) Kitamoto, K., Kimura, K., Gomi, K., and Kumagai, C., Electrophoretic karyotype and gene assignment to chromosomes of Aspergillus oryzae. Biosci. Biotechnol. Biochem., 58, 1467-1470 (1994).
- 36) Todd, R. B. and Andrianopoulos, A., Evolution of a fungal regulatory gene family: the Zn(II)2Cys6 binuclear cluster DNA binding motif. Fungal. Genet. Biol., 21, 388-405 (1997).
- 37) Kim, J. and Michels, C. A., The MAL63 gene of Saccharomyces encodes a cysteine-zinc finger protein. Curr. Genet., 14, 319-323 (1988).
- 38) Sollitti, P. and Marmur, J., Primary structure of the regulatory gene from the MAL6 locus of Saccharomyces carlsbergensis. Mol. Gen. Genet., 213, 56-62 (1988).
- 39) Landschulz, W. H., Johnson, P. F., and McKnight, S. L., The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science, 240, 1759-1764 (1988).
- 40) Lamb, P., McKnight, S. L., Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization. Trends Biochem. Sci., 16, 417-422 (1991).
- 41) van Heeswijck, R. and Hynes, M. J., The amdR product and a CCAAT-binding factor bind to adjacent, possibly overlapping DNA sequences in the promoter region of the Aspergillus nidulans amdS gene. Nucleic Acids Res., 19, 2655-2660 (1991).
- 42) Kato, M., Aoyama, A., Naruse, F., Tateyama, Y., Hayashi, K., Miyazaki, M., Papagiannopoulos, P., Davis, M. A., Hynes, M. J., Kobayashi, T., and Tsukagoshi, N., The Aspergillus nidulans CCAAT-binding factor AnCP/AnCF is a heteromeric protein analogous to the HAP complex of Saccharomyces cerevisiae. Mol. Gen. Genet., 257, 404-411 (1998).
- 43) Steidl, S., Papagiannopoulos, P., Litzka, O., Andrianopoulos, A., Davis, M. A., Brakhage, A. A., and Hynes, M. J., AnCF, the CCAAT binding complex of Aspergillus nidulans, contains products of the hapB, hapC, and hapE genes and is required for activation by the pathway-specific regulatory gene amdR. Mol. Cell. Biol., 19, 99-106 (1999).
- 44) Ni, B. and Needleman, R. B., Identification of the upstream activating sequence of MAL and the binding sites for the MAL63 activator of Saccharomyces cerevisiae. Mol. Cell. Biol., 10, 3797-3800 (1990).
- 45) Levine, J., Tanouye, L., and Michels, C. A., The UAS MAL is a bidirectional promotor element required for the expression of both the MAL61 and MAL62 genes of the Saccharomyces MAL6 locus. Curr. Genet., 22, 181-189 (1992).
- 46) Sirenko, O. I., Ni, B., and Needleman, R. B., Purification and binding properties of the Mal63p activator of Saccharomyces cerevisiae. Curr. Genet., 27, 509-516 (1995).
- 47) Reece, R. J. and Ptashne, M., Determinants of binding-site specificity among yeast C6 zinc cluster proteins. Science, 261, 909-911 (1993).
- 48) Fillinger, S. and Felenbok, B., A newly identified gene cluster in Aspergillus nidulans comprises five novel genes localized in the alc region that are controlled both by the specific transactivator AlcR and the general carbon-catabolite repressor CreA. Mol. Microbiol., 20, 475-488 (1996).
- . 1992. p. 319- 414.
- 50) Mueller, P. P. and Hinnebusch, A. G., Multiple upstream AUG codons mediate translational control of GCN4. Cell, 45, 201-207 (1986).
- 51) Tani, S., Kawaguchi, T., Kato, M., Kobayashi, T., and Tsukagoshi, N., A novel nuclear factor, SREB, binds to a cis-element, SRE, required for inducible expression of Aspergillus oryzae Taka-amylase A gene in Aspergillus nidulans. Mol. Gen. Genet., 263, 232-238 (2000).
- 52) Gibson, A. W., Wojciechowicz, L. A., Danzi, S. E., Zhang, B., Kim, J. H., Hu, Z., and Michels, C. A., Constitutive mutations of the Saccharomyces cerevisiae MAL-activator genes MAL23, MAL43, MAL63, and mal64. Genetics, 146, 1287-1298 (1997).
Full access
Molecular Cloning and Characterization of a Transcriptional Activator Gene, amyR, Involved in the Amylolytic Gene Expression in Aspergillus oryzae
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.