- 1) Shibata, K., Hayakawa, T., Taguchi, H., and Iwai, K., Regulation of pyridine nucleotide coenzyme metabolism. Adv. Exp. Med. Biol., 294, 207-218 (1991).
- 2) Shibata, K., Blood pyridine nucleotide levels reflect niacin equivalent intake in humans. J. Clin. Biochem. Nutr., 3, 37-45 (1987).
- 3) Shibata, K. and Matsuo, H., Effect of dietary tryptophan levels on the urinary excretion of nicotinamide and its metabolites in rats fed a niacin-free diet or a constant total protein level. J. Nutr., 120, 1191-1197 (1990).
- 4) Okamoto, H., Okada, F., and Hayaishi, O., Kynurenine metabolism in hyperthyroidism. A biochemical basis for the low NAD(P) level in hyperthyroid rat liver. J. Biol. Chem., 246, 7759-7763 (1971).
- 5) Sanada, H., Alteration of tryptophan-niacin metabolism by hormones and nutrients. Vitamins (Japan), 61, 549-562 (1987).
- 6) Shibata, K., Effects of protein-amino acids, lipid, and carbohydrate on the conversion ratio of tryptophan to niacin. Vitamins (Japan), 70, 369-382 (1996).
- 7) Shibata, K, and Toda, S., Effect of thyroxine on the conversion ratio of tryptophan to nicotinamide in rats. Biosci. Biotechnol. Biochem., 58, 1757-1762 (1994).
- 8) Hayaishi, O., Studies on the biosynthesis of NAD from tryptophan. Vitamins (Japan), 31, 107-114 (1965).
- 9) Ikeda, M., Tsuji, H., Nakamura, S., Ichiyama, A., Nishizuka, Y., and Hayaishi, O., Studies on the biosynthesis of nicotinamide adenine dinucleotide. II. A role of picolinic carboxylase in the biosynthesis of nicotinamide adenine dinucleotide from tryptophan in mammals. J. Biol. Chem., 240, 1395-1401 (1965).
- 10) Da Silva, A.C., Fried, R., and Angelis, R.C., The domestic cats as a laboratory animal for experimental nutrition studies. III. Niacin requirements and tryptophan metabolism. J. Nutr., 46, 399-409 (1952).
- 11) Nishizuka, Y. and Hayaishi, O., Enzymic synthesis of niacin nucleotides from 3-hydroxyanthranilic acid in mammalian liver. J. Biol. Chem., 238, PC483-485 (1963).
- 12) McDaniel, H.G., Reddy, W.J., and Boshell, J.M., The mechanism of inhibition of phosphoenolpyruvate carboxylase by quinolinic acid. Biochim. Biophys. Acta, 276, 543-550 (1972).
- 13) Schwarcz, R., Whetsell, W.O., Jr., and Mangano, R.M., Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain, Science, 219, 316-318 (1983).
- 14) Sanada, H., Miyazaki, M., and Takahashi, T., Regulation of tryptophan-niacin metabolism in diabetic rats. J. Nutr. Sci. Vitaminol., 26, 449-459 (1980).
- 15) Saito, K., Fujigaki, S,. Heyes, M.P., Shibata, K., Takemura, M,. Fujii, H., Wada, H., Noma, A., and Seishima, M., Mechanism of increases in L-Kynurenine and quinolinic acid in renal insufficiency. Am. J. Physiol. Renal. Physiol., 279, F565-F572 (2000).
- 16) Philips, F.S., Thiersch, J.B., and Birndorf, A., Adenine intoxication in relation to in vivo formation and deposition of 2,8-dioxyadenine in renal tubules. J. Pharmacol. Exp. Therap., 104, 20-30 (1952).
- 17) Shields, C.E., Lopas, H., and Birndorf, N.I., Investigation of nephrotoxic effects of adenine and its metabolic product, 2,8-dioxyadenine, on primates (Macaca irus). J. Clin. Pharmacol., 10, 316-322 (1970).
- 18) Pullman, M.P. and Colowick, S.P., Preparation of 2- and 6-pyridones of N1-methylnicotinamide. J. Biol. Chem., 206, 121-127 (1954).
- 19) Shibata, K., Kawada, T., and Iwai, K., Simultaneous micro-determination of nicotinamide and its major metabolites, N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-3-carboxamide, by highperformance liquid chromatography. J. Chromatogr., 424, 23-28 (1988).
- 20) Shibata, K. and Murata, K., Blood NAD as an index of niacin nutrition, Nutr. Int., 2, 177-181 (1986).
- 21) Shibata, K. and Tanaka, K., Simple measurement of blood NADP and blood levels of NAD and NADP in humans. Agric. Biol. Chem., 50, 2941-2942 (1986).
- 22) Shibata, K., Ultramicro-determination of N1-methylnicotinamide in urine by high-performance liquid chromatography. Vitamins (Japan), 61, 599-604 (1987).
- 23) Shibata, K., Fluorimetric micro-determination of kynurenic acid, an endogenous blocker of neurotoxicity, by high-performance liquid chromatography. J. Chromatogr., 430, 376-380 (1988).
- 24) Shibata, K. and Onodera, M., Simultaneous high-performance liquid chromatographic measurement of xanthurenic acid and 3-hydroxyanthranilic acid in urine. Biosci. Biotechnol. Biochem., 56, 974 (1992).
- 25) Shibata, K. and Onodera, M., Measurement of 3-hydroxyanthranilic acid and anthranilic acid in urine by high-performance liquid chromatography. Agric. Biol. Chem., 55, 143-148 (1991).
- 26) Mawatari, K., Oshida, K., Iinuma, F., and Watanabe, M., Determination of quinolinic acid in human urine by liquid chromatography with fluorimetric detection. Anal. Chim. Acta, 302, 179-183 (1995).
- 27) Shibata, K., Tryptophan-niacin metabolism in alloxan diabetic rats and partial prevention of alloxan diabetes by nicotinamide. Agric. Biol. Chem., 51, 811-816 (1987).
- 28) Ichiyama, A., Nakamura, S., Kawai, H., Honjo, T., Nishizuka, Y., Hayaishi, O., and Senoh, S., Studies on the metabolism of the benzene ring of tryptophan in mammalian tissue. II. Enzymic formation of α-aminomuconic acid from 3-hydroxyanthranilic acid. J. Biol. Chem., 240, 740-749 (1965).
- 29) Shibata, K. and Iwai, K., Isolation and properties of crystalline quinolinate phosphoribosyltransferase. Biochim. Biophys. Acta, 611, 280-288 (1980).
- 30) Yokozawa, T., Zheng, P.D., Oura, H., and Koizumi, F., Animal model of adenine-induced chronic renal failure in rats. Nephron, 44, 230-234 (1986).
- 31) Shibata, K., Effect of ethanol feeding and growth on the tryptophan-niacin metabolism in rats. Agric. Biol. Chem., 54, 2953-2959 (1990).
- 32) Shibata, K. and Onodera, M. Changes in the conversion rate of tryptophan-nicotinamide according to dietary fat and protein levels. Biosci. Biotechnol. Biochem., 56, 1104-1108 (1992).
- 33) Shibata, K. Nutritional factors that regulate on the conversion of L-tryptophan to niacin. Adv. Exp. Med. Biol., 467, 711-716 (1999).
- 34) Egashira, Y., Nakagawa, A., Ohta, T., Shibata, K., and Sanada, H. Effect of dietary linoleic acid on the tryptophan-niacin metabolism in streptozotocin-diabetic rats. Comp. Biochem. Physiol., 111, 539-545 (1995).
- 35) Shibata, K., Morita, M., and Matsuo H. Urinary excretion of nicotinamide and its metabolites in alloxandiabetic rats fed on a niacin-free diet. Agric. Biol. Chem., 53, 3353-3354 (1989).
- 36) Sanada, H., Miyazaki, M., and Takahashi, T., Regulation of tryptophan-niacin metabolism in diabetic rats. J. Nutr. Sci. Vitaminol., 26, 449-459 (1980).
- 37) Sanada, H. and Miyazaki, M. Effect of pituitary hormones on α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase in rats. J. Nutr. Sci. Vitaminol., 26, 607-616 (1980).
Full access
Influence of Adenine-induced Renal Failure on Tryptophan-niacin Metabolism in Rats
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.