199
Views
38
CrossRef citations to date
0
Altmetric
Original Articles

Identification of the Bile Acid-binding Region in the Soy Glycinin A1aB1b Subunit

, &
Pages 2395-2401 | Received 22 May 2002, Accepted 28 Jun 2002, Published online: 22 May 2014

  • 1) Nagata, C., Takatsuka, N., Kurisu, Y., and Shimizu, H., Decreased serum total cholesterol concentration is associated with high intake of soy products in Japanese men and women. J. Nutr., 128, 209-213 (1998).
  • 2) Wong, W. W., Smith, E. O., Stuff, J. E., Hachey, D. L., Heird, W. C., and Pownell, H. J., Cholesterol-lowering effect of soy protein in normocholesterolemic and hypercholesterolemic men. Am. J. Clin. Nutr., 68, 1385S-1389S (1998).
  • 3) Carroll, K. K., and Kurowska, E. M., Soy consumption and cholesterol reduction: review of animal and human studies. J. Nutr., 125, 594S-597S (1995).
  • 4) Huff, M. W., and Carroll, K. K., Effects of dietary protein on turnover, oxidation, and absorption of cholesterol and on steroid excretion in rabbits. J. Lipid Res., 21, 546-558 (1980).
  • 5) Potter, S. M., Overview of proposed mechanisms for the hypocholesterolemic effect of soy. J. Nutr., 125, 606S-611S (1995).
  • 6) Sirtori, C. R., and Lovati, M. R., Soy proteins and Cardiovascular disease. Curr. Atheroscler. Rep., 3, 47-53 (2001).
  • 7) Dietschy, J. M., Turley, S. D., and Spady, D. K., Role of the liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J. Lipid. Res., 34, 1637-1659 (1993).
  • 8) Wilson, M. D., and Rudel, L. L., Review of cholesterol absorption with emphasis on dietary and biliary cholesterol. J. Lipid Res., 35, 943-955 (1994).
  • 9) Nagaoka, S., Miwa, K., Eto, M., Kuzuya, Y., Hori, G., and Yamamoto, K., Soy protein peptic hydrolysate with bound phospholipids decreases micellar solubility and cholesterol absorption in rats and Caco-2 cells. J. Nutr., 129, 1725-1730 (1999).
  • 10) Iwami, K., Sakakibara, K., and Ibuki, F., Involvement of post-digestion ‘hydrophobic’ peptides in plasma cholesterol-lowering effect of dietary plant proteins. Agric. Biol. Chem., 50, 1217-1222 (1986).
  • 11) Sugano, M., Yamada, Y., Yoshida, K., Hashimoto, Y., Matsuo, T., and Kimoto, M., The hypocholesteroletic action of the undigested fraction of soybean protein in rats. Atherosclerosis, 72, 115-122 (1988).
  • 12) Sugano, M., Goto, S., Yamada, Y., Yoshida, K., Hashimoto, Y., Matsuo, T., and Kimoto, M., Cholesterol-lowering activity of various undigested fractions of soybean protein in rats. J. Nutr., 120, 977-985 (1990).
  • 13) Makino, S., Nakashima, H., Minami, K., Moriyama, R., and Takao, S., Bile acid-binding protein from soybean seed: isolation, partial characterization and insulin-stimulating activity. Agric. Biol. Chem., 52, 803-809 (1988).
  • 14) Minami, K., Moriyama, R., Kitagawa, Y., and Makino, S., Identification of soybean protein components that modulate the action of insulin in vitro. Agric. Biol. Chem., 54, 511-517 (1990).
  • 15) Katsube, T., Kurisaka, N., Ogawa, M., Maruyama, N., Ohtsuka, R., Utsumi, S., and Takaiwa, F., Accumulation of soybean glycinin and its assembly with the glutelins in rice. Plant Physiol., 120, 1063-1073 (1999).
  • 16) Sanger, F., Nicklen, S., and Coulson, A. R., DNA sequencing with chain-termination inhibitors. Proc. Natl. Acad. Sci. USA, 74, 5463-5467 (1977).
  • 17) Kim, C. S., Kamiya, S., Kanamori, J., Utsumi, S., and Kito, M., High-level expression, purification and functional properties of soybean proglycinin from Escherichia coli. Agric. Biol. Chem., 54, 1543-1550 (1990).
  • 18) Bradford, M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254 (1976).
  • 19) Bird, R. P., Mercer, N. J., and Draper, H. H., Animal models for the study of nutrition and human disease: colon cancer, atherosclerosis, and osteoporosis. In “Advance in Nutrition Research” vol. 7, ed. Draper, H. H., Plenum Press, New York, pp. 155-186 (1985).
  • 20) Hori, T., Matsumoto, K., Sakaitani, Y., Sato, M., and Morotomi, M., Effect of dietary deoxycholic acid and cholesterol on fecal steroid concentration and its impact on the colonic crypt cell proliferation in azoxymethane-treated rats. Cancer Lett., 124, 79-84 (1998).
  • 21) Azuma, N., Machida, K., Saeki, T., Kanamoto, R., and Iwami, K., Preventive effect of soybean resistant proteins against experimental tumorigenesis in rat colon. J. Nutr. Sci. Vitaminol. (Tokyo), 46, 23-29 (2000).
  • 23) Takenaka, Y., Utsumi, S., and Yoshikawa, M., Introduction of enterostatin (VPDPR) and a related sequence into soybean proglycinin A1aB1b subunit by site-directed mutagenesis. Biosci. Biotechnol. Biochem., 64, 2731-2733 (2000).
  • 25) Motoba, N., Doyama, N., Yamada, Y., Maruyama, N., Utsumi, S., and Yoshikawa, M., Design and production of genetically modified soybean protein with anti-hypertensive activity by incorporating potent analogue of ovokinin (2-7). FEBS. Lett., 497, 50-54 (2001).
  • 22) Kanamoto, R., Azuma, N., Miyamoto, T., Saeki, T., Tsuchihashi, Y., and Iwami, K., Soybean resistant proteins interrupt an enterohepatic circulation of bile acids and suppress liver tumorigenesis induced by azoxymethane and dietary deoxycholate in rats. Biosci. Biotechnol. Biochem., 65, 999-1002 (2001).
  • 24) Takenaka, Y., Utsumi, S., and Yoshikawa, M., Introduction of a low molecular weight agonist peptide for complement C3a receptor into soybean proglycinin A1aB1b subunit by site-directed mutagenesis. Biosci. Biotechnol. Biochem., 65, 1202-1205 (2001).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.