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Original Articles

Mepanipyrim, a Novel Inhibitor of Pharmacologically Induced Golgi Dispersion

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Pages 139-150 | Received 07 Aug 2002, Accepted 10 Sep 2002, Published online: 22 May 2014

  • 1) Farquhar, M. G., and Palade, G. E., The Golgi apparatus: 100 years of progress and controversy. Trends Cell Biol., 8, 2-10 (1998).
  • 2) Lippincott-Schwartz, J., Roberts, T. H., and Hirschberg, K., Secretory protein trafficking and organelle dynamics in living cells. Annu. Rev. Cell Dev. Biol., 16, 557-589 (2000).
  • 3) Barr, F. A., The Golgi apparatus: going round in circles? Trends Cell Biol., 12, 101-104 (2002).
  • 4) Puthenveedu, M. A., and Linstedt, A. D., In search of an essential step during mitotic Golgi disassembly and inheritance. Exp. Cell Res., 271, 22-27 (2001).
  • 5) Check, E., Will the real Golgi please stand up. Nature, 416, 780-781 (2002).
  • 6) Dinter, A., and Berger, E. G., Golgi-disturbing agents. Histochem. Cell Biol., 109, 571-590 (1998).
  • 7) Maeno, S., Miura, I., Masuda, K., and Nagata, T., Mepanipyrim (KIF-3535), a new pyrimidine fungicide. Brighton Crop Prot. Conf.—Pests and Diseases, 2, 415-422 (1990).
  • 8) Miura, I., Kamakura, T., Maeno, S., Hayashi, S., and Yamaguchi, I., Inhibition of enzyme secretion in plant pathogens by mepanipyrim, a novel fungicide. Pestic. Biochem. Physiol., 48, 222-228 (1994).
  • 9) Miura, I., Muroi, M., Shiragami, N., Yamaguchi, I., and Takatsuki, A., Effects of mepanipyrim on intracellular trafficking: a comparative study on its effects on exocytic and endocytic trafficking of proteins, sphingolipids, and cholesterol. Biosci. Biotechnol. Biochem., 60, 1690-1697 (1996).
  • 10) Masner, P., Muster, P., and Schmid, J., Possible methionine biosynthesis inhibition by pyrimidinamine fungicides. Pestic. Sci., 42, 163-166 (1994).
  • 11) Fritz, R., Lanen, C., Colas, V., and Leroux, P., Inhibition of methionine biosynthesis in Botrytis cinerea by the anilinopyrimidine fungicide pyrimenthanil. Pestic. Sci., 49, 40-46 (1997).
  • 12) Muroi, M., Takasu, A., Yamasaki, M., and Takatsuki, A., Folimycin (concanamycin A), an inhibitor of V-type H+-ATPase, blocks cell-surface expression of virus-envelope glycoproteins. Biochem. Biophys. Res. Commun., 193, 999-1005 (1993).
  • 13) Takatsuki, A., and Tamura, G., Brefeldin A, a specific inhibitor of intracellular translocation of vesicular stomatitis virus G protein: intracellular accumulation of high-mannose type G protein and inhibition of its cell surface expression. Agric. Biol. Chem., 49, 899-902 (1985).
  • 14) Klausner, R. D., Donaldson, J. G., and Lippincott-Schwartz, J., Brefeldin A: insights into the control of membrane traffic and organelle structure. J. Cell Biol., 116, 1071-1080 (1992).
  • 15) Kornfeld, R., and Kornfeld, S., Assembly of asparagine-linked oligosaccharides. Annu. Rev. Biochem., 54, 631-664 (1985).
  • 16) Iida, K., Tsuyama, S., Kashio, N., and Murata, F., Subcompartment sugar residues of gastric surface mucous cells studied with labeled lectins. Histochemistry, 95, 329-335 (1991).
  • 17) Donaldson, J. G., Finazzi, D., and Klausner, R. D., Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide on ARF protein. Nature, 360, 350-352 (1992).
  • 18) Helms, J. B., and Rothman, J. E., Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF. Nature, 360, 352-354 (1992).
  • 19) Donaldson, J. G., Lippincott-Schwartz, J., Bloom, G. S., Kreis, T., and Klausner, R. D., Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action. J. Cell Biol., 111, 2295-2306 (1990).
  • 20) Scheel, J., Pepperkok, R., Lowe, M., Griffiths, G., and Kreis, T. E., Dissociation of coatomer from membranes is required for brefeldin A-induced transfer of Golgi enzymes to the endoplasmic reticulum. J. Cell Biol., 137, 319-333 (1997).
  • 21) Fujiwara, T., Takami, N., Misumi, Y., and Ikehara, Y., Nordihydroguaiaretic acid blocks protein transport in the secretory pathway causing redistribution of Golgi proteins into the endoplasmic reticulum. J. Biol. Chem., 273, 3068-3075 (1998).
  • 22) Drecktrah, D., de Figureueiredo, P., Mason, R. M., and Brown, W. J., Retrograde trafficking of both Golgi complex and TGN markers to the ER induced by nordihydroguaiaretic acid and cyclofenil diphenol. J. Cell Sci., 111, 951-965 (1998).
  • 23) de Figureueiredo, P., and Brown, W. J., Clofibrate inhibits membrane trafficking to the Golgi complex and induces its retrograde movement to the endoplasmic reticulum. Cell Biol. Toxicol., 15, 311-323 (1999).
  • 25) Kuroiwa, N., Nakamura, M., Tagaya, M., and Takatsuki, A., Arachidonyltrifluoromethy ketone, a phospholipase A2 antagonist, induces dispersal of both Golgi stack- and trans Golgi network-resident proteins throughout the cytoplasm. Biochem. Biophys. Res. Commun., 281, 582-588 (2001).
  • 26) Chege, N. W., and Pfeffer, S. R., Compartmentation of the Golgi complex: brefeldin A distinguishes trans-Golgi cisternae from the trans-Golgi network. J. Cell Biol., 111, 893-899 (1990).
  • 27) Takatsuki, A., Nakamura, M., and Kono, Y., Possible implication of Golgi-nucleating function for the centrosome. Biochem. Biophys. Res. Commun., 291, 494-500 (2002).
  • 29) Hunt, L. A., Davidson, S. K., and Golemboski, D. B., Unusual heterogeneity in the glycosylation of the G protein of the Hazelhurst strain of vesicular stomatitis virus. Arch. Biochem. Biophys., 226, 347-356 (1983).
  • 30) Thyberg, J., and Moskalewski, S., Microtubules and the organization of the Golgi complex. Exp. Cell Res., 159, 1-16 (1985).
  • 24) Nakamura, M., Kuroiwa, N., Kono, Y., and Takatsuki, A., Characterization of clofibrate-induced retrograde Golgi membrane movement to the endoplasmic reticulum: clofibrate distinguishes the Golgi from the trans Golgi network. Biosci. Biotechnol. Biochem., 65, 1812-1823 (2001).
  • 28) Nakamura, M., Kuroiwa, N., Kono, Y., and Takatsuki, A., Glucosylceramide synthesis inhibitors block pharmacologically induced dispersal of the Golgi and anterograde membrane flow from the endoplasmic reticulum: implication of sphingolipid metabolism in maintenance of the Golgi architecture and anterograde membrane flow. Biosci. Biotechnol. Biochem., 65, 1369-1378 (2001).

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