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Bioscience, Biotechnology, and Biochemistry Volume 67, 2003 - Issue 12
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Original Articles

SS33410, an Inhibitor of V-ATPase, Blocks Intracellular Protein Transport of the VSV-G Protein in the Golgi Compartment

Dae-Hyun SEOGDepartment of Microbiology, College of Medicine, Inje UniversityBusan, 614-735, Korea
Pages 2591-2597 | Received 25 Jun 2003, Accepted 03 Sep 2003, Published online: 22 May 2014

  • 1) Keenan, R. J., Freymann, D. M., Stroud, R. M., and Walter, P., The signal recognition particle. Annu. Rev. Biochem., 70, 755-775 (2001).
  • 2) Kowarik, M., Kung, S., Martoglio, B., and Helenius, A., Protein folding during cotranslational translocation in the endoplasmic reticulum. Mol. Cell., 10, 769-778 (2002).
  • 3) Nicchita, C. V., A platform for compartmentalized protein synthesis: protein translation and translocation in the ER. Curr. Opin. Cell. Biol., 14, 412-416 (2002).
  • 4) Schnell, D. J., and Hebert, D. N., Protein translocons: multifunctional mediators of protein translocation across membranes. Cell, 112, 491-505 (2003).
  • 5) Pfeffer, S., Membrane domains in the secretory and endocytic pathways. Cell, 112, 507-517 (2003).
  • 6) Aridor, M., and Traub, L. M., Cargo selection in vesicular transport: the making and breaking of a coat. Traffic, 3, 537-546 (2002).
  • 7) Antonny, B., and Schekman, R., ER export: public transportation by the COPII coach. Curr. Opin. Cell. Biol., 13, 438-443 (2001).
  • 8) Helenius, A., and Aebi, M., Intracellular functions of N-linked glycans. Science, 291, 2364-2369 (2001).
  • 9) Kornfeld, R., and Kornfeld, S., Assembly of asparagine-linked oligosaccharides. Annu. Rev. Biochem., 54, 631-664 (1985).
  • 10) Bannykh, S. I., Nishimura, N., and Balch, W. E., Getting into the Golgi. Trends Cell. Biol., 1, 21-25 (1998).
  • 11) Farquhar, M. G., and Palade, G. E., The Golgi apparatus: 100 years of progress and controversy. Trends Cell. Biol., 1, 2-10 (1998).
  • 12) Takatsuki, A., and Tamura, G., Brefeldin A, a specific inhibitor of intracellular translocation of vesicular stomatitis virus G protein: intracellular accumulation of high-mannose type G protein and inhibition of its cell surface expression. Agric. Biol. Chem., 49, 899-902 (1985).
  • 13) Klausner, R. D., Donaldson, J. G., and Lippincott-Schwartz, J., Brefeldin A: insights into the control of membrane traffic and organelle structure. J. Cell. Biol., 116, 1071-1080 (1992).
  • 14) Lippincott-Schwartz, J., Yuan, L. C., Bonifacino, J. S., and Klausner, R. D., Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER. Cell, 56, 801-813 (1989).
  • 15) Fujiwara, T., Oda, K., Yokota, S., Takatsuki, A., and Ikehara, Y., Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum. J. Biol. Chem., 263, 18545-18552 (1988).
  • 16) Lippincott-Schwartz, J., Yuan, L., Tipper, C., Amherdt, M., Orci, L., and Klausner, R. D., Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell, 67, 601-616 (1991).
  • 17) Donaldson, J. G., Finazzi, D., and Klausner, R. D., Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein. Nature, 360, 350-352 (1992).
  • 18) Helms, J. B., and Rothman, J. E., Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF. Nature, 360, 352-354 (1992).
  • 19) Seog, D.-H., Yamasaki, M., and Takatsuki, A., SS33410, an inhibitor for inflammation, blocks the intracellular transport of VSV G glycoprotein in BHK cells. Biochem. Biophys. Res. Commun., 199, 1073-1080 (1994).
  • 20) Uchida, E., Ohsumi, Y., and Anraku, Y., Purification of yeast vacuolar membrane H+-ATPase and enzymological discrimination of three ATP-driven proton pumps in Saccharomyces cerevisiae. Methods Enzymol., 157, 544-562 (1988).
  • 21) Serrano, R., H+-ATPase from plasma membranes of Saccharomyces cerevisiae and Avena sativa roots: purification and reconstitution. Methods Enzymol., 157, 533-544 (1988).
  • 22) Mellman, I., Fuchs, R., and Helenius, A., Acidification of the endocytic and exocytic pathways. Annu. Rev. Biochem., 55, 663-700 (1986).
  • 23) Forgac, M., Structure and function of vacuolar class of ATP-driven proton pumps. Physiol. Rev., 69, 765-796 (1989).
  • 24) Muroi, M., Shiragami, N., Nagao, K., Yamasaki, M., and Takatsuki, A., Folimycin (concanamycin A), a specific inhibitor of V-ATPase, blocks intracellular translocation of the glycoprotein of vesicular stomatitis virus before arrival to the Golgi apparatus. Cell Struct. Funct., 18, 139-149 (1993).
  • 25) Weck, P. K., Carroll, A. R., Shattuck, D. M., and Wagner, R. R., Use of UV irradiation to identify the genetic information of vesicular stomatitis virus responsible for shutting off cellular RNA synthesis. J. Virol., 30, 746-753 (1979).
  • 26) Hunt, L. A., Davidson, S. K., and Golemboski, D. B., Unusual heterogeneity in the glycosylation of the G protein of the hazelhurst strain of vesicular stomatitis virus. Arch. Biochem. Biophys., 226, 347-356 (1983).
  • 27) Bergmann, J. E., Tokuyasu, K. T., and Singer, S. J., Passage of an integral membrane protein, the vesicular stomatitis virus glycoprotein, through the Golgi apparatus en route to the plasma membrane. Proc. Natl. Acad. Sci. USA, 78, 1746-1750 (1981).
  • 28) Saraste, M., Oxidative phosphorylation at the fin de siecle. Science, 283, 1488-1493 (1999).
  • 29) Davoust, J., Gruenberg, J., and Howell, K. E., Two threshold values of low pH block endocytosis at different stages. EMBO J., 6, 3601-3609 (1987).
  • 30) van Weert, A. W., Dunn, K. W., Gueze, H. J., Maxfield, F. R., and Stoorvogel, W., Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. J. Cell. Biol., 130, 821-834 (1995).
  • 31) Chanat, E., and Huttner, W. B., Milieu-induced, selective aggregation of regulated secretory proteins in the trans-Golgi network. J. Cell. Biol., 115, 1505-1519 (1991).
  • 32) Mellman, I., The importance of being acid: the role of acidification in intracellular membrane traffic. J. Exp. Biol., 172, 39-45 (1992).
  • 33) Xu, H., and Shields, D., Prosomatostatin processing in permeabilized cells. Endoproteolytic cleavage is mediated by a vacuolar ATPase that generates an acidic pH in the trans-Golgi network. J. Biol. Chem., 269, 22875-22881 (1994).
  • 34) Maxfield, F. R., and Yamashiro, D. J., “Intracellular Trafficking of Proteins”, Cambridge University Press, Cambridge, pp. 157-182 (1991).
  • 35) Kim, J. H., Johannes, L., Goud, B., Antony, C., Lingwood, C. A., Daneman, R., and Grinstein, S., Noninvasive measurement of the pH of the endoplasmic reticulum at rest and during calcium release. Proc. Natl. Acad. Sci. USA, 95, 2997-3002 (1998).
  • 36) Kneen, M., Farinas, J., Li, Y., and Verkman, A. S., Green fluorescent protein as a noninvasive intracellular pH indicator. Biophys. J., 74, 1591-1599 (1998).
  • 37) Demaurex, N., Furuya, W., D'Souza, S., Bonifacino, J. S., and Grinstein, S., Mechanism of acidification of the trans-Golgi network (TGN). In situ measurements of pH using retrieval of TGN38 and furin from the cell surface. J. Biol. Chem., 273, 2044-2051 (1998).
  • 38) Kim, J. H., Lingwood, C. A., Williams, D. B., Furuya, W., Manolson, M. F., and Grinstein, S., Dynamic measurement of the pH of the Golgi complex in living cells using retrograde transport of the verotoxin receptor. J. Cell. Biol., 134, 1387-1399 (1996).
  • 39) Llopis, J., McCaffery, J. M., Miyawaki, A., Farquhar, M. G., and Tsien, R. Y., Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins. Proc. Natl. Acad. Sci. USA, 95, 6803-6808 (1998).
  • 40) Chapman, R. E., and Munro, S., Retrieval of TGN proteins from the cell surface requires endosomal acidification. EMBO J., 13, 2305-2312 (1994).
  • 41) Stearns, T., Willingham, M. C., Botstein, D., and Kahn, R. A., ADP-ribosylation factor is functionally and physically associated with the Golgi complex. Proc. Natl. Acad. Sci. USA, 87, 1238-1242 (1990).
  • 42) Zeuzem, S., Feick, P., Zimmermann, P., Haase, W., Kahn, R. A., and Schulz, I., Intravesicular acidification correlates with binding of ADP-ribosylation factor to microsomal membranes. Proc. Natl. Acad. Sci. USA, 89, 6619-6623 (1992).

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