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Original Articles

Evidence of Isozymes for Δ6 Fatty Acid Desaturase in Rat Hepatocytes

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Pages 451-454 | Received 11 Sep 2002, Accepted 28 Oct 2002, Published online: 22 May 2014

  • 1) Cook, H. W., Fatty acid desaturation and chain elongation in eukaryotes. In “Biochemistry of Lipids, Lipoproteins and Membranes”, eds. Vance, D. E., and Vance, J. E., Elsevier Science, Amsterdam, pp. 129-152 (1996).
  • 2) Aki, T., Shimada, Y., Inagaki, K., Higashimoto, H., Kawamoto, S., Shigeta, S., Ono, K., and Suzuki, O., Molecular cloning and functional characterization of rat Δ-6 fatty acid desaturase. Biochem. Biophys. Res. Commun., 255, 575-579 (1999).
  • 3) D'Andrea, S., Guillou, H., Jan, S., Catheline, D., Thibault, J. N., Bouriel, M., Rioux, V., and Legrand, P., The same rat Δ6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis. Biochem. J., 364, 49-55 (2002).
  • 4) Sprecher, H., Luthria, D. L., Mohammed, B. S., and Baykousheva, S. P., Reevaluation of the pathways for the biosynthesis of polyunsaturated fatty acids. J. Lipid Res., 36, 2471-2477 (1995).
  • 5) Rodriguez, A., Sarda, P., Boulot, P., Leger, C. L., and Descomps, B., Differential effect of N-ethyl maleimide on Δ6-desaturase activity in human fetal liver toward fatty acids of the n-6 and n-3 series. Lipids, 34, 23-30 (1999).
  • 6) Marzo, I., Alava, M. A., Pineiro, A., and Naval, J., Biosynthesis of docosahexaenoic acid in human cells: evidence that two different Δ 6-desaturase activities may exist. Biochim. Biophys. Acta, 1301, 263-272 (1996).
  • 7) Marquardt, A., Stöhr, H., White, K., and Weber, B. H., cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family. Genomics, 66, 175-183 (2000).
  • 8) Aki, T., Nagahata, Y., Ishihara, K., Tanaka, Y., Morinaga, T., Higashiyama, K., Akimoto, K., Fujikawa, S., Kawamoto, S., Shigeta, S., Ono, K., and Suzuki, O., Production of arachidonic acid by filamentous fungus, Mortierella alliacea strain YN-15. J. Am. Oil Chem. Soc., 78, 599-604 (2001).
  • 9) Okayasu, T., Nagao, M., Ishibashi, T., and Imai, Y., Purification and partial characterization of linoleoyl-CoA desaturase from rat liver microsomes. Arch. Biochem. Biophys., 206, 21-28 (1981).

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