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Bioscience, Biotechnology, and Biochemistry Volume 69, 2005 - Issue 12
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Original Articles

Combined Effects of Dietary Protein Type and Fat Level on the Body Fat-Reducing Activity of Conjugated Linoleic Acid (CLA) in Rats

Asuka AKAHOSHIFaculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
,
Kazunori KOBAFaculty of Nursing and Nutrition, Siebold University of Nagasaki
,
Rie ENMOTOFaculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
,
Kazuko NISHIMURAFaculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
,
Yukiko HONDAFaculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
,
Miyuki MINAMIFaculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
,
Keiko YAMAMOTOFaculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
,
Toshio IWATAHealthy Foods Department, The Nisshin OilliO Group, Ltd.
,
Yoshie YAMAUCHIHealthy Foods Department, The Nisshin OilliO Group, Ltd.
,
Kentaro TSUTSUMIHealthy Foods Department, The Nisshin OilliO Group, Ltd.
&
Michihiro SUGANOFaculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
 show all
Pages 2409-2415 | Received 21 Jul 2005, Accepted 19 Aug 2005, Published online: 22 May 2014

  • 1) Pariza, M. W., Park, Y., and Cook, M. E., Conjugated linoleic acid and the control of cancer and obesity. Toxicol. Sci., 52, 107–110 (1999).
  • 2) Pariza, M. W., Park, Y., and Cook, M. E., The biologically active isomers of conjugated linoleic acid. Prog. Lipid Res., 40, 283–298 (2001).
  • 3) Kritchevsky, D., Antimutagenic and some other effects of conjugated linoleic acid. Br. J. Nutr., 83, 459–465 (2000).
  • 4) Siems, W. G., Grune, T., Hasselwander, O., and Kramer, K., Conjugated linoleic acid. In “Nutraceuticals in Health and Disease Prevention”, eds. Kramer, K., Hoppe, P. P., and Packer, L., Marcel Dekker, New York, pp. 257–288 (2001).
  • 5) Parodi, P. W., Conjugated linoleic acid. Food Aust., 54, 96–99 (2002).
  • 6) Mensink, R. P., Metabolic and health effects of isomeric fatty acid. Curr. Opin. Lipidol., 16, 27–30 (2005).
  • 7) Kelly, G. S., Conjugated linoleic acid: a review. Altern. Med. Rev., 6, 367–382 (2001).
  • 8) Whale, K. W., Heys, S. D., and Rotondo, D., Conjugated linoleic acids: are they beneficial or detrimental to health? Prog. Lipid Res., 43, 553–587 (2004).
  • 9) Riserus, U., Smedman, A., Basu, S., and Vesssy, B., Metabolic effects of conjugated linoleic acid in humans: the swedish experience. Am. J. Clin. Nutr., 79, 1146S–1148S (2004).
  • 10) Gaullier, J. M., Halse, J., Hoye, K., Kristiansen, K., Fagertun, H., Vik, H., and Gudmundsen, O., Conjugated lionleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans. Am. J. Clin. Nutr., 79, 1118–1125 (2004).
  • 11) Malpuech-Brugere, C., Verboeket-van de Venne, W. P., Mensink, R. P., Arnal, M. A., Morio, B., Brandolini, M., Saebo, A., Lassel, T. S., Chardigny, J. M., Sebedio, J. L, and Beaufrere, B., Effects of two conjugated linoleic acid isomers on body fat mass in overweight humans. Obes. Res., 12, 591–598 (2004).
  • 12) Terpstra, A. H., Effect of conjugated linoleic acid on body composition and plasma lipids in humans: an overview of the literature. Am. J. Clin. Nutr., 79, 352–361 (2004).
  • 13) Gaullier, J. M., Halse, J., Hoye, K., Kristiansen, K., Fagertun, H., Vik, H., and Gudmundsen, O., Supplementation with conjugated linoleic acid for 24 months is well tolerated by and reduces body fat mass in healthy, overweight humans. J. Nutr., 135, 778–784 (2005).
  • 14) Moloney, F., Yeow, T. P., Mullen, A., Nolan, J. J., and Roche, H. M., Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. Am. J. Clin. Nutr., 80, 887–895 (2004).
  • 15) Riserus, U., Vessby, B., Arner, P., and Zethelius, B., Supplementation with trans10cis12-conjugated linoleic acid induces hyperproinsulinaemia in obese men: close association with impaired insulin sensitivity. Diabetologia, 47, 1016–1019 (2004).
  • 16) Basu, S., Riserus, U., Turpeinen, A., and Vessby, B., Conjugated linoleic acid induces peroxidation in men with abdominal obesity. Clin. Sci.(London), 99, 511–516 (2000).
  • 17) Sugano, M., Akahoshi, A., Koba, K., Tanaka, K., Okumura, T., Matsuyama, H., Goto, Y., Miyazaki, T., Murao, K., Yamasaki, M., Nonaka, M., and Yamada, K., Dietary manipulation of body fat-reducing potential of conjugated linoleic acid in rats. Biosci. Biothechnol. Biochem., 65, 2535–2541 (2001).
  • 18) Akahoshi, A., Koba, K., Ichinose, F., Kaneko, M., Shimoda, A., Nonaka, K., Yamasaki, Y., Iwata, T., Yamauchi, Y., Tsutsumi, K., and Sugano, M., Dietary protein modulates the effect of CLA on lipid metabolism in rats. Lipids, 39, 25–30 (2004).
  • 19) Tsuboyama-Kasaoka, N., Miyazaki, H., Kasaoka, S., and Ezaki, O., Increasing the amount of fat in a conjugated linoleic acid-supplemented diet reduces lipodystrohy in mice. J. Nutr., 133, 1793–1799 (2003).
  • 20) Reeves, P. G., Nielsen, F. H., and Fahey, G. C., AIN-93 Purified diets for laboratory rodents: final report of the american institute of nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J. Nutr., 123, 1939–1951 (1993).
  • 21) Bieber, L. L., Abraham, T., and Helmrath, T., A rapid spectrophotometric assay for carnitine palmitoyltransferase. Anal. Biochem., 50, 509–518 (1972).
  • 22) Volgarev, M. N., Vysotosky, V. G., Meshcheryakova, V. A., Yatsyshina, T. A., and Steinke, F. H., Evaluation of isolated soy protein foods in weight reduction with obese hypercholesterolemic and normocholesterolemic obese individuals. Nutr. Rep. Int., 36, 61–72 (1989).
  • 23) Anderson, J. W., Johnstone, B. M., and Cook-Newell, M. E., Meta-analysis of the effects of soy protein intake on serum lipids. N. Engl. J. Med., 333, 276–282 (1995).
  • 24) Tonstad, S., Smerud, K., and Hoie, L., A Comparison of the effect of 2 doses of soy protein or casein on serum lipids, serum lipoproteins, and plasma total homocysteine in hypercholesterolemic subjects. Am. J. Clin. Nutr., 76, 78–84 (2002).
  • 25) Doerrler, W., Feingold, K. R., and Grunfeld, C., Cytokines induce catabolic effects in cultured adipocytes by multiple mechanisms. Cytokine, 6, 478–484 (1994).
  • 26) Hotamisligil, G. S., The role of TNF-alpha and TNF receptors in obesity and insulin resistance. J. Intern. Med., 245, 621–625 (1999).
  • 27) Masuzaki, H., Ogawa, Y., Aizawa-Abe, M., Hosoda, K., Suga, J., Ebihara, K., Satoh, N., Iwai, H., Inoue, G., Nishimura, H., Yoshimasa, Y., and Nakao, K., Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: usefulness of leptin for the treatment of obesity-associated diabetes. Diabetes, 48, 1615–1622 (1999).
  • 28) Frederich, R. C., Hamann, A., Anderson, S., Lollmann, B., Lowell, B. B., and Flier, J. S., Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat. Med., 1, 1311–1314 (1995).
  • 29) Collins, S., Kuhn, C. M., Petro, A. E., Swick, A. G., Chrunyk, B. A., and Surwit, R. S., Role of leptin in fat regulation. Nature, 380, 677 (1996).
  • 30) Wang, Q., Bing, C., Al-Barazanji, K., Mossakowaska, D. E., Wang, X. M., McBay, D. L., Neville, W. A., Taddayon, M., Pickavance, L., Dryden, S., Thomas, M. E., McHale, M. T., Gloyer, I. S., Wilson, S., Buckingham, R., Arch, J. R., Trayhurn, P., and Williams, G., Interactions between leptin and hypothalamic neuropeptide Y neurons in the control of food intake and energy homeostasis in the rat. Diabetes, 46, 335–341 (1997).
  • 31) Akahoshi, A., Goto, Y., Murao, K., Miyazaki, T., Yamasaki, M., Nonaka, M., Yamada, K., and Sugano, M., Conjugated linoleic acid reduces body fats and cytokine levels of mice. Biosci. Biotechnol. Biochem., 66, 916–920 (2002).
  • 32) Pajvani, U. B., and Scherer, P. E., Adiponectin: systemic contributor to insulin sensitivity. Curr. Diab. Rep., 3, 207–213 (2003).
  • 33) Tschritter, O., Fritsche, A., Thamer, C., Haap, M., Shirkavand, F., Rahe, S., Staiger, H., Maerker, E., Haring, H., and Stumvoll, M., Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism. Diabetes, 52, 239–243 (2003).
  • 34) Nagasawa, A., Fukui, K., Funahashi, T., Maeda, N., Shimomura, I., Kihara, S., Waki, M., Takamatsu, K., and Matsuzawa, Y., Effects of soy protein diet on the expression of adipose genes and plasma adiponectin. Horm. Metab. Res., 34, 635–639 (2002).
  • 35) Ryu, M. H., and Cha, Y. S., The effects of a high-fat or high-sucrose diet on serum lipid profiles, hepatic acyl-CoA synthetase, carnitine palmitoyltransferase-I, and the acetyl-CoA carboxylase mRNA levels in rats. J. Biochem. Mol. Biol., 36, 312–318 (2003).
  • 36) Gleenen, S. N., Blazquez, C., Gleenen, M. J., Sloet van Oldruitenborgh-Oosterbaan, M. M., and Beynen, A. C., High fat intake lowers hepatic fatty acid synthesis and raises fatty acid oxidation in aerobic muscle in shetland ponies. Br. J. Nutr., 86, 31–36 (2001).
  • 37) Watkins, C., Easy ways to get more soy into your diet. INFORM, 15, 10–12 (2004).

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