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Bioscience, Biotechnology, and Biochemistry Volume 69, 2005 - Issue 2
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Original Articles

The Necessity of Niacin in Rats Fed on a High Protein Diet

Naoko KIMURALaboratories of Food Science and Nutrition, Department of Life Style Studies, School of Human Cultures, The University of Shiga Prefecture
,
Tsutomu FUKUWATARILaboratories of Food Science and Nutrition, Department of Life Style Studies, School of Human Cultures, The University of Shiga Prefecture
,
Ryuzo SASAKILaboratories of Food Science and Nutrition, Department of Life Style Studies, School of Human Cultures, The University of Shiga Prefecture
&
Katsumi SHIBATALaboratories of Food Science and Nutrition, Department of Life Style Studies, School of Human Cultures, The University of Shiga Prefecture
Pages 273-279 | Received 29 Jun 2004, Accepted 04 Nov 2004, Published online: 22 May 2014

  • 1) Shibata, K., Mushiage, M., Kondo, T., Hayakawa, T., and Tsuge, H., Effects of vitamin B6 deficiency on the conversion ratio of tryptophan to niacin. Biosci. Biotechnol. Biochem., 59, 2060–2063 (1995).
  • 2) Pullman, M. E., and Colowick, S. P., Preparation of 2- and 6-pyridones of N 1-methylnicotinamide. J. Biol. Chem., 206, 121–127 (1954).
  • 3) Shibata, K., Kawada, T., and Iwai, K., Simultaneous micro-determination of nicotinamide and its major metabolites, N 1-methyl-2-pyridone-5-carboxamide and N 1-methyl-4-pyridone-3-carboxamide, by high-performance liquid chromatography. J. Chromatogr., 424, 23–28 (1988).
  • 4) Shibata, K., The metabolism of niacin in each organ and the biological method for assessing the nutritional status of niacin in the rat. Vitamins (in Japanese), 61, 39–56 (1987).
  • 5) Shibata, K., and Matsuo, H., Effect of dietary tryptophan levels on the urinary excretion of nicotinamide and its metabolites in rats fed a niacin-free diet or a constant total protein level. J. Nutr., 120, 1191–1197 (1990).
  • 6) Shibata, K., Ultramicro-determination of N 1-methylnicotinamide in urine by high-performance liquid chromatography. Vitamins (in Japanese), 61, 599–604 (1987).
  • 7) Shibata, K., Fluorimetric micro-determination of kynurenic acid, an endogeneous blocker of neurotoxicity, by high-performance liquid chromatography. J. Chromatogr., 430, 376–380 (1988).
  • 8) Shibata, K., and Onodera, M., Simultaneous high-performance liquid chromatographic measurement of xanthurenic acid and 3-hydroxyanthranilic acid in urine. Biosci. Biotechnol. Biochem., 56, 974 (1992).
  • 9) Shibata, K., Tryptophan–niacin metabolism in alloxane diabetic rats and partial prevention of alloxane by nicotinamide. Agric. Biol. Chem., 51, 811–816 (1987).
  • 10) Tobes, M. C., and Mason, M., L-Kynurenine aminotransferase and L-α-aminoadipate aminotransferase. I. Evidence for identity. Biochem. Biophys. Res. Commun., 62, 390–397 (1975).
  • 11) Shibata, K., and Toda, S., Effects of thyroxine on the conversion ratio of tryptophan to nicotinamide in rats. Biosci. Biotechnol. Biochem., 58, 1757–1762 (1994).
  • 12) Ichiyama, A., Nakamura, S., Kawai, H., Honjo, T., Nishizuka, Y., Hayaishi, O., and Senoh, T., Studies on the benzene ring of tryptophan in mammalian tissues. II. Enzymic formation of α-aminomuconic acid from 3-hydroxyanthranilic acid. J. Biol. Chem., 240, 740–749 (1965).
  • 13) Shibata, K., Murata, K., Hayakawa, T., and Iwai, K., Effect of dietary orotic acid on the levels of liver and blood NAD in rats. J. Nutr. Sci. Vitaminol., 31, 265–278 (1985).
  • 14) Shibata, K., The catabolism of nicotinamide in riboflavin-deficient rats. Vitamins (in Japanese), 64, 589–595 (1990).
  • 15) Sanada, H., Takahashi, T., and Miyazaki, M., Effects of dietary fat and protein on the activity of α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase and the urinary excretion of niacin metabolites in rats. J. Nutr. Sci. Vitaminol., 31, 327–337 (1985).
  • 16) Shibata, K., and Onodera, M., Changes in the conversion rate of tryptophan–nicotinamide according to dietary fat and protein levels. Biosci. Biotechnol. Biochem., 56, 1104–1108 (1992).
  • 17) Yess, N., Price, J. M., Brown, R. R., Swan, P. B., and Linkswiler, H., Vitamin B6 depletion in man: urinary excretion of tryptophan metabolites. J. Nutr., 84, 229–236 (1964).
  • 18) Yeh, J. K., and Brown, R. R., Effects of vitamin B-6 deficiency and tryptophan loading on urinary excretion of tryptophan metabolites in mammals. J. Nutr., 107, 261–271 (1977).
  • 19) “Dietary Reference Intakes: For Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline”, Standing Committee on the Scientific Evaluation of Dietary Reference Intakes and Its Panel on Folate, Other B Vitamins, and Choline and Subcommittee on Upper Reference Levels of Nutrients, Food and Nutrition Board, Institute of Medicine, National Academy Press, Washington, D.C., pp. 123–149 (1998).
  • 20) Okada, M., Shibuya, M., and Akazawa, T., Dietary protein as a factor affecting vitamin B6 requirements. J. Nutr. Sci. Vitaminol., 44, 37–45 (1998).
  • 21) Shibata, K., Fukuwatari, T., and Sugimoto, E., Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats. Biosci. Biotechnol. Biochem., 65, 1339–1346 (2001).

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