- 1) Garfinkel, L., Buring, C., and Heath, C. W., Changing trends: an overview of breast cancer incidence and mortality. Cancer Supplement, 74, 222–227 (1994).
- 2) Ravandi-Kashani, F., and Hayes, T. G., Male breast cancer: a review of literature. Eur. J. Cancer, 34, 1341–1347 (1998).
- 3) Zhang, S. M., Willett, W. C., Selhub, J., Hunter, D. J., Giovannucci, E. L., Holmes, M. D., Colditz, G. A., and Hankinson, S. E., Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer. J. Natl. Cancer Inst., 95, 373–380 (2003).
- 4) Molina, A., Oka, T., Munoz, S. M., Chikamori-Aoyama, M., Kuwahata, M., and Natori, Y., Vitamin B6 suppresses growth and expression of albumin gene in human hepatoma cell line HepG2. Nutr. Cancer, 28, 206–211 (1997).
- 5) Komatsu, S., Watanabe, H., Oka, T., Tsuge, H., Nii, H., and Kato, N., Vitamin B-6-supplemented diets compared with a low vitamin B-6 diet suppress azoxymethane-induced colon tumorigenesis in mice by reducing cell proliferation. J. Nutr., 131, 2204–2207 (2001).
- 6) Shimada, D., Fukuda, A., Kawaguch, H., Kato, N., Yoshida, H., Kanocchi, H., and Oka, T., The effect of high dose of pyridoxine on mammary tumorigenesis. Nutr. Cancer, in press.
- 7) DiSorbo, D. M., Wagner, R. Jr., and Nathanson, L., In vivo and in vitro inhibition of B16 melanoma growth by vitamin B6. Nutr. Cancer, 7, 43–52 (1985).
- 8) DiSorbo, D. M., and Litwack, G., Vitamin B6 kills hepatoma cells in culture. Nutr. Cancer, 3, 216–222 (1983).
- 9) DiSorbo, D. M., and Nathanson, L., High-dose pyridoxal supplemented culture medium inhibits the growth of a human malignant melanoma cell line. Nutr. Cancer, 5, 10–15 (1983).
- 10) Vermaak, W. J., Barnard, H. C., van Dalen, E. M., and Potgieter, G. M., Correlation between pyridoxal-5′-phosphate levels and the percentage activation of aspartate aminotransferase enzyme in haemolysate and plasma during in vitro incubation studies with different B6 vitamers. Enzyme, 35, 215–224 (1986).
- 11) Martial, L., Zardivar, J., Bull, P., Venegas, A., and Valensuela, P., Inactivation of rat liver RNA polymerase I and II and yeast RNA polymerase I by pyridoxal 5′-phosphate: evidence for the participation of lysyl residue at the active site. Biochemistry, 14, 4907–4911 (1975).
- 12) Venegas, A., Martial, J., and Valenzuela, P., Active site-directed inhibition of E. coli DNA-dependent RNA polymerase by pyridoxal 5′-phosphate. Biochem. Biophys. Res. Commun., 55, 1053–1059 (1973).
- 13) Basu, A., Tirumalai, R. S., and Modak, M. J., Substrate binding in human immunodeficiency virus reverse transcriptase. J. Biol. Chem., 264, 8746–8752 (1989).
- 14) Diffley, J. F. X., Affinity labeling the DNA polymerase a complex from Drosophila melanogaster embryos. J. Biol. Chem., 263, 14669–14677 (1988).
- 15) Modak, M. J., Observation of the pyridoxal 5′-phosphate inhibition of DNA polymerase I. Biochemistry, 15, 3620–3626 (1975).
- 16) Fischer, E. H., Kent, A. B., Snyder, E. R., and Krebs, E. G., The reaction of sodium borohydrate with muscle phosphorylase. J. Am. Chem. Soc., 80, 2906–2907 (1958).
- 17) Oka, T., Komori, N., Kuwahata, M., Suzuki, I., Okada, M., and Natori, Y., Effect of vitamin B6 deficiency on the expression of glycogen phosphorylase mRNA in rat liver and skeletal muscle. Experientia, 50, 127–129 (1994).
- 18) Oka, T., Komori, N., Kuwahata, M., Sassa, T., Suzuki, I., Okada, M., and Natori, Y., Vitamin B6 deficiency causes activation of RNA polymerase and general enhancement of gene expression in rat liver. FEBS Lett., 331, 162–164 (1993).
- 19) Oka, T., Komori, N., Kuwahata, M., Okada, M., and Natori, Y., Vitamin B6 modulates expression of albumin gene by inactivating tissue-specific DNA-binding protein in rat liver. Biochem. J., 309, 243–248 (1995).
- 20) Ehrenshaft, M., Bilski, P., Li, M. Y., Chignell, C. F., and Daub, M. E., A highly conserved sequence is a novel gene involved in de novo vitamin B6 biosynthesis. Proc. Natl. Acad. Sci. USA, 95, 9374–9378 (1999).
Full access
Vitamin B6 Suppresses Growth of the Feline Mammary Tumor Cell Line FRM
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.