645
Views
36
CrossRef citations to date
0
Altmetric
Original Articles

The Fibrinolytic Activity of a Novel Protease Derived from a Tempeh Producing Fungus, Fusarium sp. BLB

, , , &
Pages 2184-2189 | Received 19 Mar 2007, Accepted 01 Jun 2007, Published online: 22 May 2014

  • 1) Sumi, H., Hamada, H., Tsushima, H., Mihara, H., and Muraki, H., A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet. Experientia, 43, 1110–1111 (1987).
  • 2) Steinkraus, K. H., Yap, B. H., Van Buren, J. P., Provvidenti, M. I., and Hand, D. B., Studies on tempeh - an Indonesian fermented soybean food. Food Res., 25, 777–788 (1960).
  • 3) Okada, N., Development of tempeh microbiology. Nippon Jozo Kyokaishi (in Japanese), 81, 464–469 (1986).
  • 4) Nout, M. J. R., and Rombouts, F. M., Recent developments in tempe research. J. Appl. Bacteriol., 69, 609–633 (1990).
  • 5) Denter, J., Rehm, H. J., and Bisping, B., Changes in the contents of fat-soluble vitamins and provitamins during tempe fermentation. Int. J. Food Microbiol., 45, 129–134 (1998).
  • 6) Keuth, S., and Bisping, B., Formation of vitamins by pure cultures of tempeh moulds and bacteria during the tempeh solid substrate fermentation. J. Appl. Bacteriol., 75, 427–434 (1993).
  • 7) Keuth, S., and Bisping, B., Vitamin B12 production by Citrobacter freundii or Klebsiella pneumoniae during tempeh fermentation and proof of enterotoxin absence by PCR. Appl. Environ. Microbiol., 60, 1495–1499 (1994).
  • 8) Cassidy, A., Hanley, B., and Lamuela-Raventos, R. M., Isoflavones, lignans and stilbenes – origins, metabolism and potential importance to human health. J. Sci. Food Agric., 80, 1044–1062 (2000).
  • 9) Kalavi, F. N. M., Muroki, N. M., Omwega, A. M., and Mwadime, R. K. N., Effects of tempe yellow maize porridge and milk yellow maize porridge on growth rate, diarrhoea and duration of rehabilitation of malnourished children. East Afr. Med. J., 73, 427–431 (1996).
  • 10) Karyadi, D., and Lukito, W., Beneficial effects of tempeh in disease prevention and treatment. Nutr. Rev., 54, 94–98 (1996).
  • 11) Sumi, H., and Okamoto, T., Thrombolytic activity of an aqueous extract of tempe. Nippon Kasei Gakkaishi (in Japanese), 54, 337–342 (2003).
  • 12) Sherry, S., Recombinant tissue plasminogen activator (rt-PA): is it the thrombolytic agent of choice for an evolving acute myocardial infarction? Am. J. Cardiol., 59, 984–989 (1987).
  • 13) Sasaki, K., Moriyama, S., Tanaka, Y., Sumi, H., Toki, N., and Robbins, K. C., The transport of 125I-labeled human high molecular weight urokinase across the intestinal tract in a dog model with stimulation of synthesis and/or release of plasminogen activators. Blood, 66, 69–75 (1985).
  • 14) Sumi, H., Maruyama, M., Yoneta, T., and Mihara, H., Activation of plasma fibrinolysis after intrarectal administration of high molecular weight urokinase and its derivative. Acta Haematol., 70, 289–295 (1983).
  • 15) Toki, N., Sumi, H., Sasaki, K., Boreisha, I., and Robbins, K. C., Transport of urokinase across the intestinal tract of normal human subjects with stimulation of synthesis and/or release of urokinase-type proteins. J. Clin. Invest., 75, 1212–1222 (1985).
  • 16) Ueda, M., Kubo, T., Miyatake, K., and Nakamura, T., Purification and characterization of fibrinolytic alkaline protease from Fusarium sp. BLB. Appl. Microbiol. Biotechnol., 74, 331–338 (2007).
  • 17) Ochman, H., Gerber, A. S., and Hartl, D. L., Genetic applications of an inverse polymerase chain reaction. Genetics, 120, 621–623 (1988).
  • 18) Laemmli, U. K., Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680–685 (1970).
  • 19) Astrup, T., and Mullertz, S., The fibrin plate method for estimating fibrinolytic activity. Arch. Biochem. Biophys., 40, 346–351 (1952).
  • 20) Miyata, K., Hirai, S., Yashiki, T., and Tomoda, K., Intestinal absorption of Serratia protease. J. Appl. Biochem., 2, 111–116 (1980).
  • 21) Moriya, N., Nakata, M., Nakamura, M., Takaoka, M., Iwasa, S., Kato, K., and Kakimura, A., Intestinal absorption of serrapeptase [TSP] in rats. Biotechnol. Appl. Biochem., 20, 101–108 (1994).
  • 22) Katayama, K., and Fujita, T., Studies on biotransformation of elastase. II. Intestinal absorption of 131I-labelled elastase in vivo. Biochim. Biophys. Acta, 288, 181–189 (1972).
  • 23) Papp, M., Fehár, S., Folly, G., and Horváth, E. J., Absorption of pancreatic lipase from the duodenum into lymphatics. Experientia, 33, 1191–1192 (1977).
  • 24) Avakian, S., Further studies on the absorption of chymotrypsin. Clin. Pharmacol. Ther., 5, 712–715 (1964).
  • 25) Warshaw, A. L., Walker, W. A., Cornell, R., and Isselbacher, K., Small intestinal permeability to macromolecules. Transmission of horseradish peroxidase into mesenteric lymph and portal blood. Lab. Invest., 25, 675–684 (1971).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.