- 1) Staessen, J., Gasowski, J., Wang, J. G., Thijs, L., Hond, E. D., Boissel, J. P., Coope, J., Ekbom, T., Gueyffier, F., Liu, L., Kelikowske, K., Pocock, S., and Fagard, R. H., Risks of untreated and treated systolic hypertension in the elderly: meta-analysis of outcome trials. Lancet, 355, 865–872 (2000).
- 2) Staessen, J. A., Wang, J., Bianchi, G., and Birkenhager, W. H., Essential hypertension. Lancet, 361, 1629–1641 (2003).
- 3) Hansen, K., Nyman, U., Smitt, U. W., Adersen, A., Gudiksen, L., Rajasekharan, S., and Pushpangadan, P., In vitro screening of traditional medicines for anti-hypertensive effect based on inhibition of angiotensin converting enzyme (ACE). J. Ethnopharmacol., 48, 43–51 (1995).
- 4) Somanadhan, B., Varughese, G., Palpu, P., Sreedharan, R., Gudiksen, L., Smitt, U. W., and Nyman, U., An ethnopharmacological survey for potential angiotensin converting enzyme inhibitors from Indian medicinal plants. J. Ethnopharmacol., 65, 103–112 (1999).
- 5) Actis-Goretta, L., Ottaviani, J. I., and Fraga, C. G., Inhibition of angiotensin converting enzyme activity by flavonol-rich foods. J. Agric. Food Chem., 54, 229–234 (2006).
- 6) Ottaviani, J. I., Actis-Goretta, L., Villordo, J. J., and Fraga, C. G., Procyanidin structure defines the extent and specificity of angiotensin I converting enzyme inhibition. Biochimie, 88, 359–365 (2006).
- 7) Cignarella, A., Nastasi, M., Cavalli, E., and Puglisi, L., Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb. Res., 84, 311–322 (1996).
- 8) Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai-Le, P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S., Anti-diabetic properties of the Canadian lowbush blueberry Vaccinium angustifolium Ait. Phytomedicine, 13, 612–623 (2006).
- 9) Cushman, D. W., and Cheung, H. S., Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung. Biochem. Pharmacol., 20, 1637–1648 (1971).
- 10) Suzuki, T., Ishikawa, N., and Meguro, H., Angiotensin I-converting enzyme inhibiting activity in foods. Nippon Nogeikagaku Kaishi (in Japanese), 57, 1143–1146 (1983).
- 11) Matsui, T., Li, C. H., Tanaka, T., Maki, T., Osajima, Y., and Matsumoto, K., Depressor effect of wheat germ hydrolysate and its novel angiotensin I-converting enzyme inhibitory peptide, Ile-Val-Tyr, and the metabolism in rat and human plasma. Biol. Pharm. Bull., 23, 427–431 (2001).
- 12) Frenoux, J. M., Prost, E. D., Belleville, J. L., and Prost, J. L., A polyunsaturated fatty acid diet lowers blood pressure and improves antioxidant status in spontaneously hypertensive rats. J. Nutr., 131, 39–45 (2001).
- 13) Inoue, N., Nagao, K., Hirata, J., Wang, Y. M., and Yanagita, T., Conjugated linoleic acid prevents the development of essential hypertension in spontaneously hypertensive rats. Biochem. Biophys. Res. Commun., 323, 679–684 (2004).
- 14) Bolterman, R. J., Manriquez, M. C., Ortiz-Ruiz, M. C., Juncos, L. A., and Romero, J. C., Effects of captopril on the renin angiotensin system, oxidative stress, and endothelin in normal and hypertensive rats. Hypertension, 46, 943–947 (2005).
- 15) Han, P., Chu, Z. X., Shen, F. M., Xie, H. H., and Su, D. F., Synergism of hydrochlorothiazide and nitrendipine on reduction of blood pressure and blood pressure variability in spontaneously hypertensive rats. Acta Pharmacol. Sin., 27, 1575–1579 (2006).
- 16) Fujii, M., Matsumura, N., Mito, K., Shimizu, T., Kuwahara, M., Sugano, S., and Karaki, H., Antihypertensive effects of peptides in autolysate of bonito bowels on spontaneously hypertensive rats. Biosci. Biotechnol. Biochem., 57, 2186–2188 (1993).
- 17) Shin, Z. I., Yu, R., Park, S. A., Chung, D. K., Ahn, C. W., Nam, H. S., Kim, K. S., and Lee, H. J., His-His-Leu, an angiotensin I converting enzyme inhibitory peptide derived from Korean soybean paste, exerts antihypertensive activity in vivo. J. Agric. Food Chem., 49, 3004–3009 (2001).
- 18) Li, G. H., Qu, M. R., Wan, J. Z., and You, J. M., Antihypertensive effect of rice protein hydrolysate with in vitro angiotensin I-converting enzyme inhibitory activity in spontaneously hypertensive rats. Asia Pac. J. Clin. Nutr., 16, 275–280 (2007).
- 19) Terencio, M. C., Sanz, M. J., and Paya, M., Antihypertensive action of a procyanidin glycoside from Rhamnus lycioides. J. Ethnopharmacol., 31, 109–114 (1991).
- 20) Cheng, J. T., Hsu, F. L., and Chen, H. F., Antihypertensive principles from the leaves of Melastoma candidum. Planta Med., 59, 405–407 (1993).
- 21) Liu, J. C., Hsu, F. L., Tsai, J. C., Chan, P., Liu, J. Y., Thomas, G. N., Tomlinson, B., Lo, M. Y., and Lin, J. Y., Antihypertensive effects of tannins isolated from traditional Chinese herbs as non-specific inhibitors of angiontensin converting enzyme. Life Sci., 73, 1543–1555 (2003).
Full access
Effect of Vaccinium ashei reade Leaves on Angiotensin Converting Enzyme Activity in Vitro and on Systolic Blood Pressure of Spontaneously Hypertensive Rats in Vivo
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.