Advanced search
Publication Cover
Bioscience, Biotechnology, and Biochemistry Volume 71, 2007 - Issue 10
Journal homepage
232
Views
7
CrossRef citations to date
0
Altmetric
Original Articles

Excess Leucine Intake Induces Serine Dehydratase in Rat Liver

Bo ZHONGDepartment of Biological Resource Chemistry, Kyoto Prefectural University
,
Shunsuke SAKAIDepartment of Biological Resource Chemistry, Kyoto Prefectural University
,
Tohru SAEKIDepartment of Biological Resource Chemistry, Kyoto Prefectural University
&
Ryuhei KANAMOTODepartment of Biological Resource Chemistry, Kyoto Prefectural University
Pages 2614-2617 | Received 10 Aug 2007, Accepted 06 Sep 2007, Published online: 22 May 2014

  • 1) Ogawa, H., Fujioka, M., Su, Y., Kanamoto, R., and Pitot, H. C., Nutritional regulation and tissue-specific expression of the serine dehydratase gene in rat. J. Biol. Chem., 266, 20412–20417 (1991).
  • 2) Noda, C., Yakiyama, M., Nakamura, T., and Ichihara, A., Requirements of both glucocorticoids and glucagons as co-inducers for activation of transcription of the serine dehydratase gene in cultured rat hepatocytes. J. Biol. Chem., 263, 14764–14768 (1988).
  • 3) Su, Y., Kanamoto, R., Miller, D. A., Ogawa, H., and Pitot, H. C., Regulation of the expression of the serine dehydratase gene in the kidney and liver of the rat. Biochem. Biophys. Res. Commun., 170, 892–899 (1990).
  • 4) Kanamoto, R., Su, Y., and Pitot, H. C., Hormonal regulation of serine dehydratase gene expression in liver and kidney of the adrenalectomized rat. Mol. Endocrinol., 5, 1661–1668 (1991).
  • 5) Imai, S., Kanamoto, R., Yagi, I., Kotaru, M., Saeki, T., and Iwami, K., Response of the inducion of rat liver serine dehydratase to changes in the dietary protein requirement. Biosci. Biotechnol. Biochem., 67, 383–387 (2003).
  • 6) Kanamoto, R., Fujita, K., Kumasaki, M., Imai, S., Kotaru, M., Saeki, T., and Iwami, K., Inverse correlation between the nitrogen balance and induction of rat liver serine dehydratase (SDH) by dietary protein. Biosci. Biotechnol. Biochem., 68, 888–893 (2004).
  • 7) Lynch, C. J., Huston, S. M., Paston, B. J., Vaval, A., and Vary, T. C., Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats. Am. J. Physiol. Endocrinol. Metab., 283, E824–835 (2002).
  • 8) Yoshizawa, F., Kimball, S. R., and Vary, T. C., Effect of dietary protein on translation initiation in rat skeletal muscle and liver. Am. J. Physiol., 273, E814–820 (1998).
  • 9) Azuma, N., Machida, K., Saeki, T., Kanamoto, R., and Iwami, K., Preventive effect of soybean resistant protein against experimental tumorigenesis in rat colon. J. Nutr. Sci. Vitaminol. (Tokyo), 46, 23–29 (2000).
  • 10) Chomczynski, P., and Sacchi, N., Single-step method of RNA isolation by acid guanidinium thiocyanate–phenol–chloroform extraction. Anal. Biochem., 162, 156–159 (1987).
  • 11) Shimomura, Y., Hawes, J. W., Murakami, T., and Harris, R. A., Regulation of branched-chain amino acid catabolism: nutritional and hormonal regulation of activity and expression of the branch-chain α-keto acid dehydrogenase kinase. Curr. Opin. Clin. Nutr. Metab. Care, 4, 419–423 (2001).
  • 12) Gietzen, D. W., and Magrum, L. J., molecular mechanisms in the brain involved in the anorexia of branched-chain amino acid deficiency. J. Nutr., 131, 851S–855S (2001).
  • 13) Marchesini, G., Bianchi, G., Merli, M., Amodio, P., Panella, C., Loquercio, C., Rossi Fanelli, F., and Abbiati, R., Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial. Gastroenterology, 124, 1792–1801 (2003).
  • 14) Hiroshige, K., Sonta, T., Suda, T., Kanegae, K., and Ohtani, A., Oral supplementation of branched-chain amino acid improves nutritional status in elderly patients on chronic haemodialysis. Nephrol. Dial. Transplant., 16, 1856–1862 (2001).
  • 15) Nitsch, D., Boshart, M., and Schutz, G., Activation of the tyrosine aminotransferase gene is dependent on synergy between liver-specific and hormone-responsive elements. Proc. Natl. Acad. Sci. USA, 90, 5479–5483 (1993).
  • 16) Faber, S., O’Brien, R. M., Imai, E., Granner, D. K., and Chalkley, R., Dynamic aspects of DNA/protein interactions in the transcriptional initiation complex and the hormone-responsive domains of the phosphoenolpyruvate carboxykinase promoter in vivo. J. Biol. Chem., 268, 24976–24985 (1993).
  • 17) Jost, J. P., Khairallah, E. A., and Pitot, H. C., Studies on the induction and repression of enzymes in rat liver. V. Regulation of the rate of synthesis and degradation of serine dehydratase by dietary amino acids and glucose. J. Biol. Chem., 243, 3057–3066 (1968).
  • 18) Nakagawa, H., Miura, S., Kimura, H., and Kanatsuna, T., Studies on substrate induction of serine dehydratase of rat liver. J. Biochem. (Tokyo), 66, 549–564 (1969).
  • 19) Anthony, J. C., Yoshizawa, F., Anthony, T. G., Vary, T. C., Jefferson, L. S., and Kimball, S. R., Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway. J. Nutr., 130, 2413–2419 (2000).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.