- 1) DeLuca, H. F., Overview of general physiologic features and functions of vitamin D. Am. J. Clin. Nutr., 80, 1689S–1696S (2004).
- 2) Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schutz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P., and Evans, R. M., The nuclear receptor superfamily: the second decade. Cell, 83, 835–839 (1995).
- 3) Nemere, I., and Farach-Carson, M. C., Membrane receptors for steroid hormones: a case for specific cell surface binding sites for vitamin D metabolites and estrogens. Biochem. Biophys. Res. Commun., 248, 443–449 (1998).
- 4) Civitelli, R., Kim, Y. S., Gunsten, S. L., Fujimori, A., Huskey, M., Avioli, L. V., and Hruska, K. A., Nongenomic activation of the calcium message system by vitamin D metabolites in osteoblast-like cells. Endocrinology, 127, 2253–2262 (1990).
- 5) Buitrago, C. G., Pardo, V. G., de Boland, A. R., and Boland, R., Activation of RAF-1 through Ras and protein kinase Cα mediates 1α, 25(OH)2-vitamin D3 regulation of the mitogen-activated protein kinase pathway in muscle cells. J. Biol. Chem., 278, 2199–2205 (2003).
- 6) Yamauchi, J., The establishment of a HeLa cell demonstrating rapid mitogen-activated protein kinase phosphorylation in response to 1α, 25-dihydroxyvitamin D3 by stable transfection of a chick skeletal muscle cDNA library. Biosci. Biotechnol. Biochem., 70, 312–315 (2006).
- 7) Huhtakangas, J. A., Olivera, C. J., Bishop, J. E., Zanello, L. P., and Norman, A. W., The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1α, 25(OH)2-vitamin D3 in vivo and in vitro. Mol. Endocrinol., 18, 2660–2671 (2004).
- 8) Erben, R. G., Soegiarto, D. W., Weber, K., Zeitz, U., Lieberherr, M., Gniadecki, R., Moller, G., Adamski, J., and Balling, R., Deletion of deoxyribonucleic acid binding domain of the vitamin D receptor abrogates genomic and nongenomic functions of vitamin D. Mol. Endocrinol., 16, 1524–1537 (2002).
- 9) Zanello, L. P., and Norman, A. W., Rapid modulation of osteoblast ion channel responses by 1α, 25(OH)2-vitamin D3 requires the presence of a functional vitamin D nuclear receptor. Proc. Natl. Acad. Sci. USA, 101, 1589–1594 (2004).
- 10) Nguyen, T. M., Lieberherr, M., Fritsch, J., Guillozo, H., Alvarez, M. L., Fitouri, Z., Jehan, F., and Garabedian, M., The rapid effects of 1,25-dihydroxyvitamin D3 require the vitamin D receptor and influence 24-hydroxylase activity: studies in human skin fibroblasts bearing vitamin D receptor mutations. J. Biol. Chem., 279, 7591–7597 (2004).
- 11) Dokoh, S., Donaldson, C. A., Marion, S. L., Pike, J. W., and Haussler, M. R., The ovary: a target organ for 1,25-dihydroxyvitamin D3. Endocrinology, 112, 200–206 (1983).
- 12) Schwartz, Z., Ehland, H., Sylvia, V. L., Larsson, D., Hardin, R. R., Bingham, V., Lopez, D., Dean, D. D., and Boyan, B. D., 1α,25-dihydroxyvitamin D3 and 24R,25-dihydroxyvitamin D3 modulate growth plate chondrocyte physiology via protein kinase C-dependent phosphorylation of extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase. Endocrinology, 143, 2775–2786 (2002).
- 13) Yamamoto, K., Sun, W. Y., Ohta, M., Hamada, K., DeLuca, H. F., and Yamada, S., Conformationally restricted analogs of 1α,25-dihydroxyvitamin D3 and its 20-epimer: compounds for study of the three-dimensional structure of vitamin D responsible for binding to the receptor. J. Med. Chem., 39, 2727–2737 (1996).
- 14) Halloran, B. P., and DeLuca, H. F., Vitamin D deficiency and reproduction in rats. Science, 204, 73–74 (1979).
- 15) Kinuta, K., Tanaka, H., Moriwake, T., Aya, K., Kato, S., and Seino, Y., Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads. Endocrinology, 141, 1317–1324 (2000).
- 16) Johnson, L. E., and DeLuca, H. F., Vitamin D receptor null mutant mice fed high levels of calcium are fertile. J. Nutr., 131, 1787–1791 (2001).
Full access
Differential Regulation of Extracellular Signal-Related Kinase Phosphorylation by Vitamin D3 Analogs
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.