Advanced search
Publication Cover
Bioscience, Biotechnology, and Biochemistry Volume 72, 2008 - Issue 6
Journal homepage
278
Views
1
CrossRef citations to date
0
Altmetric
Original Articles

The Yeast Checkpoint Kinase Dun1 Downregulates DIN7 in the Absence of DNA Damage

Ayako YOSHITANIChemical Genetics Laboratory, RIKEN Discovery Research Institute;Graduate School of Science and Engineering, Saitama University
,
Feng LINGChemical Genetics Laboratory, RIKEN Discovery Research Institute
&
Minoru YOSHIDAChemical Genetics Laboratory, RIKEN Discovery Research Institute;Graduate School of Science and Engineering, Saitama University
Pages 1630-1634 | Received 25 Feb 2008, Accepted 27 Feb 2008, Published online: 22 May 2014

  • 1) Kang, D., and Hamasaki, N., Mitochondrial oxidative stress and mitochondrial DNA. Clin. Chem. Lab. Med., 41, 1281–1288 (2003).
  • 2) Bender, A., Krishnan, K. J., Morris, C. M., Taylor, G. A., Reeve, A. K., Perry, R. H., Jaros, E., Hersheson, J. S., Betts, J., Klopstock, T., Taylor, R. W., and Turnbull, D. M., High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat. Genet., 38, 515–517 (2006).
  • 3) Alseth, I., Eide, L., Pirovano, M., Rognes, T., Seeberg, E., and Bjoras, M., The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast. Mol. Cell. Biol., 19, 3779–3787 (1999).
  • 4) Mieczkowski, P. A., Fikus, M. U., and Ciesla, Z., Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes. Mol. Gen. Genet., 253, 655–665 (1997).
  • 5) Fikus, M. U., Mieczkowski, P. A., Koprowski, P., Rytka, J., Sledziewska-Gojska, E., and Ciesla, Z., The product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, specifically functions in mitochondria. Genetics, 154, 73–81 (2000).
  • 6) Koprowski, P., Fikus, M. U., Dzierzbicki, P., Mieczkowski, P., Lazowska, J., and Ciesla, Z., Enhanced expression of the DNA damage-inducible gene DIN7 results in increased mutagenesis of mitochondrial DNA in Saccharomyces cerevisiae. Mol. Genet. Genomics, 269, 632–639 (2003).
  • 7) Yoshitani, A., Yoshida, M., and Ling, F., A novel cis-acting element required for DNA damage-inducible expression of yeast DIN7. Biochem. Biophys. Res. Commun., 365, 183–188 (2008).
  • 8) Weinert, T., DNA damage checkpoints update: getting molecular. Curr. Opin. Genet. Dev., 8, 185–193 (1998).
  • 9) Zhou, B. B., and Elledge, S. J., The DNA damage response: putting checkpoints in perspective. Nature, 408, 433–439 (2000).
  • 10) Zhou, Z., and Elledge, S. J., DUN1 encodes a protein kinase that controls the DNA damage response in yeast. Cell, 75, 1119–1127 (1993).
  • 11) Huang, M., and Elledge, S. J., Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae. Mol. Cell. Biol., 17, 6105–6113 (1997).
  • 12) Huang, M., Zhou, Z., and Elledge, S. J., The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor. Cell, 94, 595–605 (1998).
  • 13) Ling, F., Makishima, F., Morishima, N., and Shibata, T., A nuclear mutation defective in mitochondrial recombination in yeast. EMBO J., 14, 4090–4101 (1995).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.