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Bioscience, Biotechnology, and Biochemistry Volume 72, 2008 - Issue 9
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Original Articles

Ansaetherone, a New Radical Scavenger from Streptomyces sp.

Toshikazu KOMODASchool of Food, Agricultural and Environmental Sciences, Miyagi University
,
Kazuaki AKASAKAGraduate School of Life Sciences, Tohoku University
&
Akira HIROTALaboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka
Pages 2392-2397 | Received 24 Apr 2008, Accepted 29 May 2008, Published online: 22 May 2014

  • 1) Komoda, T., Kishi, M., Abe, N., Sugiyama, Y., and Hirota, A., Novel lipoxygenase inhibitors, tetrapetalone B, C, and D from Streptomyces sp. Biosci. Biotechnol. Biochem., 68, 903–908 (2004).
  • 2) Komoda, T., Yoshida, K., Abe, N., Sugiyama, Y., Imachi, M., Hirota, H., Koshino, H., and Hirota, A., Tetrapetalone A, a novel lipoxygenase inhibitor from Streptomyces sp. Biosci. Biotechnol. Biochem., 68, 104–111 (2004).
  • 3) Komoda, T., Sugiyama, Y., Abe, N., Imachi, M., Hirota, H., Koshino, H., and Hirota, A., Revised structure of tetrapetalone A and its absolute stereochemistry. Tetrahedron Lett., 44, 7417–7419 (2003).
  • 4) Komoda, T., Sugiyama, Y., Abe, N., Imachi, M., Hirota, H., and Hirota, A., Tetrapetalone A, a novel lipoxygenase inhibitor from Streptomyces sp. Tetrahedron Lett., 44, 1659–1661 (2003).
  • 5) Komoda, T., Sugiyama, Y., and Hirota, A., Biosynthesis of tetrapetalones. Org. Biomol. Chem., 5, 1615–1620 (2007).
  • 6) Ohtani, I., Kusumi, T., Kashman, Y., and Kakisawa, H., High-field FT NMR application of Mosher’s method. The absolute configurations of marine terpenoids. J. Am. Chem. Soc., 113, 4092–4096 (1991).
  • 7) Floss, H. G., Combinatorial biosynthesis-potential and problems. J. Biotechnol., 124, 242–257 (2006).
  • 8) Chen, S., Von Bamberg, D., Hale, V., Breuer, M., Hardt, B., Muller, R., Floss, H. G., Reynolds, K. A., and Leistner, E., Biosynthesis of ansatrienin (mycotrienin) and naphthomycin. Identification and analysis of two separate biosynthetic gene clusters in Streptomyces collinus Tü 1892. Eur. J. Biochem., 261, 98–107 (1999).
  • 9) Yu, T.-W., Muller, R., Muller, M., Zhang, X., Draeger, G., Kim, C. G., Leistner, E., and Floss, H. G., Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in Amycolatopsis mediterranei S699. J. Biol. Chem., 276, 12546–12555 (2001).
  • 10) Yu, T.-W., Bai, L., Clade, D., Hoffmann, D., Toelzer, S., Trinh, K. Q., Xu, J., Moss, S. J., Leistner, E., and Floss, H. G., The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum. Proc. Natl. Acad. Sci. USA, 99, 7968–7973 (2002).
  • 11) Abe, N., Murata, T., and Hirota, A., Novel DPPH radical scavengers, bisorbicillinol and demethyltrichodimerol, from a fungus. Biosci. Biotechnol. Biochem., 62, 661–666 (1998).
  • 12) Abe, N., Murata, T., and Hirota, A., Novel oxidized sorbicillin dimers with 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity from a fungus. Biosci. Biotechnol. Biochem., 62, 2120–2126 (1998).
  • 13) Chen, Y.-C., Sugiyama, Y., Abe, N., Kuruto-Niwa, R., Nozawa, R., and Hirota, A., DPPH radical-scavenging compounds from dou-chi, a soybean fermented food. Biosci. Biotechnol. Biochem., 69, 999–1006 (2005).
  • 14) Washida, K., Abe, N., Sugiyama, Y., and Hirota, A., Novel DPPH radical scavengers, demethylbisorbibutenolide and trichopyrone, from a fungus. Biosci. Biotechnol. Biochem., 71, 1052–1057 (2007).

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