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Original Articles

Lignans from the Fruits of Forsythia suspensa (Thunb.) Vahl Protect High-Density Lipoprotein during Oxidative Stress

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Pages 2750-2755 | Received 11 Jun 2008, Accepted 07 Jul 2008, Published online: 22 May 2014

  • 1) Stampfer, M. J., Sacks, M. D., Salvini, S., Willett, S. C., and Hennekens, C. H., A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction. N. Engl. J. Med., 325, 373–381 (1991).
  • 2) Rubins, H. B., Robins, S. J., Iwane, M. K., Boden, W. E., Elam, M. B., Fye, C. L., Gordon, D. J., Schaefer, E. J., Schectman, G., and Wittes, J. T., Rationale and design of the department of veterans affairs high density lipoprotein cholesterol intervention trial (HIT) for secondary prevention of coronary artery disease in men with low high density lipoprotein cholesterol and desirable low density lipoprotein cholesterol. Am. J. Cardiol., 71, 45–52 (1993).
  • 3) Rubin, E. M., Krauss, R. M., Spangler, E. A., Verstuyft, J. G., and Clift, S. M., Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI. Nature, 353, 265–267 (1991).
  • 4) Francis, G. A., High density lipoprotein oxidation: in vitro susceptibility and potential in vivo consequences. Biochim. Biophys. Acta, 1483, 217–235 (2000).
  • 5) Nofer, J. R., Kehrel, B., Fobker, M., Levkau, B., Assmann, G., and von Eckardstein, A., HDL and arteriosclerosis: beyond reverse cholesterol transport. Atherosclerosis, 161, 1–16 (2002).
  • 6) Alsheikh-Ali, A. A., Kuvin, J. T., and Karas, R. H., High-density lipoprotein cholesterol in the cardiovascular equation: does the “good” still count? Atherosclerosis, 180, 217–223 (2005).
  • 7) Xinyixueyuan, “Dictionary of Traditional Chinese Medicine,” Shanghai Scientific & Technologic Press, Shanghai, pp. 1111–1113 (1977).
  • 8) Nikaido, T., Ohmoto, T., Kinoshita, T., Sankawa, U., Nishibe, S., and Hisada, S., Inhibition of cyclic AMP phosphodiesterase by lignans. Chem. Pharm. Bull., 29, 3586–3592 (1981).
  • 9) Kitagawa, S., Hisada, S., and Nishibe, S., Phenolic compounds from Forsythia leaves. Phytochemistry, 23, 1635–1636 (1984).
  • 10) Shamsur-Rouf, A. S., Ozaki, Y., Rashid, M. A., and Rui, J., Dammarane derivatives from the dried fruits of Forsythia suspensa. Phytochemistry, 56, 815–818 (2001).
  • 11) Ozaki, Y., Rui, J., and Tang, Y. T., Anti-inflammatory effect of Forsythia suspensa V(AHL) and its active principle. Biol. Pharm. Bull., 23, 365–367 (2000).
  • 12) Schinella, G. R., Tournier, H. A., Prieto, J. M., Mordujovich de Buschiazzo, P., and Ríos, J. L., Antioxidant activity of anti-inflammatory plant extracts. Life Sci., 18, 1023–1033 (2002).
  • 13) Steffan, B., Wätjen, W., Michels, G., Niering, P., Wray, V., Ebel, R., Edrada, R., Kahl, R., and Proksch, P., Polyphenols from plants used in traditional Indonesian medicine (jamu): uptake and antioxidative effects in rat H4IIE hepatoma cells. J. Pharm. Pharmacol., 57, 233–240 (2005).
  • 14) Piao, X. L., Jang, M. H., Cui, J., and Piao, X., Lignans from the fruits of Forsythia suspensa. Bioorg. Med. Chem. Lett., 18, 1980–1984 (2008).
  • 15) Qu, H., Zhang, Y., Wang, Y., Li, B., and Sun, W., Antioxidant and antibacterial activity of two compounds (forsythiaside and forsythin) isolated from Forsythia suspensa. J. Pharm. Pharmacol., 60, 261–266 (2008).
  • 16) Ferretti, G., Bacchetti, T., Menanno, F., and Curatola, G., Effect of genistein against copper-induced lipid peroxidation of human high density lipoproteins (HDL). Atherosclerosis, 172, 55–61 (2004).
  • 17) Hung, T. M., Lee, J. P., Min, B. S., Choi, J. S., Na, M., Zhang, X., Ngoc, T. M., Lee, I., and Bae, K., Magnoflorine from Coptidis Rhizoma protects high density lipoprotein during oxidant stress. Biol. Pharm. Bull., 30, 1157–1160 (2007).
  • 18) Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, P. J., Protein measurement with the folin phenol reagent. J. Biol. Chem., 193, 265–275 (1951).
  • 19) Puhl, H., Waeg, G., and Esterbauer, H., Methods to determine oxidation of low-density lipoproteins. Methods Enzymol., 233, 425–441 (1994).
  • 20) Sobal, G., and Sinzinger, H., Effect of simvastatin on the oxidation of native and modified lipoproteins. Biochem. Pharmacol., 70, 1185–1191 (2005).
  • 21) Rifici, V. A., and Khachadurian, A. K., Effects of dietary vitamin C and E supplementation on the copper mediated oxidation of HDL and on HDL mediated cholesterol efflux. Atherosclerosis, 127, 19–26 (1996).
  • 22) Garner, B., Witting, P. K., Waldeck, A. R., Christison, J. K., Raftery, M., and Stocker, R., Oxidation of high density lipoproteins. I. Formation of methionine sulfoxide in apolipoproteins AI and AII is an early event that accompanies lipid peroxidation and can be enhanced by alpha-tocopherol. J. Biol. Chem., 273, 6080–6087 (1998).
  • 23) Albertini, R., De Luca, G., Passi, A., Moratti, R., and Abuja, P. M., Chondroitin-4-sulfate protects high-density lipoprotein against copper-dependent oxidation. Arch. Biochem. Biophys., 365, 143–149 (1999).
  • 24) Nguyen, S. D., and Sok, D. E., Effect of 3,4-dihydroxyphenylalanine on Cu(2+)-induced inactivation of HDL-associated paraoxonasel and oxidation of HDL; inactivation of paraoxonasel activity independent of HDL lipid oxidation. Free Radic. Res., 38, 969–976 (2004).
  • 25) Chen, C. C., Chen, H. Y., Shiao, M. S., Lin, Y. L., Kuo, Y. H., and Ou, J. C., Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco. Planta Med., 65, 709–711 (1999).
  • 26) Eklund, P. C., Långvik, O. K., Wärnå, J. P., Salmi, T. O., Willför, S. M., and Sjöholm, R. E., Chemical studies on antioxidant mechanisms and free radical scavenging properties of lignans. Org. Biomol. Chem., 3, 3336–3347 (2005).

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