Manipulation of Natural Product Accumulation in Plants Through Genetic Engineering

REFERENCES

• Argôlo , A. C.C. , Charlwood , B. V. and Pletsch , M. 2000 . The regulation of solasodine production by Agrobacterium rhizogenes-transformed roots of Solanum aviculare . Planta Medica , (in press).
   PubMed Web of Science ®Google Scholar
• Bogorad , L. 2000 . Engineering chloroplasts: An alternative site for foreign genes, proteins, reactions and products. . TIBTECH , 18 : 257 – 263 .
   PubMed Web of Science ®Google Scholar
• Brown , J. T. , Hegarty , P. K. and Charlwood , B. V. 1987 . The toxicity of mono-terpenes to plant cell cultures. . Plant Science , 48 : 195 – 201 .
   Web of Science ®Google Scholar
• Dixon , R. A. , Lamb , C. J. , Masoud , S. , Sewalt , V. J.H. and Paiva , N. L. 1996 . Metabolic engineering: Prospects for crop improvement through the genetic manipulation of phenylpropanoid biosynthesis and defence responses: A review. . Gene , 179 : 61 – 71 .
   PubMed Web of Science ®Google Scholar
• Lodhi , A. H. and Charlwood , B. V. 1996 . Agrobacterium rhizogenes-mediated transformation of Rubia peregrina L.: In vitro accumulation of anthraquinones. . Plant Cell Tissue Organ Culture , 46 : 103 – 108 .
   Web of Science ®Google Scholar
• Lodhi , A. H. , Bongaerts , R. J.M. , Verpoorte , R. , Coomber , S. A. and Charlwood , B. V. 1996 . Expression of bacterial isochorismate synthase (EC 5.4.99.6) in transgenic root cultures of . Rubia peregrina. Plant Cell Reports , 16 : 54 – 57 .
   PubMed Web of Science ®Google Scholar
• Grotewold , E. , Chamberlin , M. , Snook , M. , Siame , B. , Butler , L. , Swenson , J. , Maddock , S. , Clair , G. St. and Bowen , B. 1998 . Engineering secondary metabolism in maize cells by ectopic expression of transcription factor. . Plant Cell , 10 : 721 – 740 .
   PubMed Web of Science ®Google Scholar
• Hashimoto , T. , Yun , D.-J. and Yamada , Y. 1993 . Production of tropane alkaloids in genetically engineered root cultures. . Phytochemistry , 32 : 713 – 718 .
   Web of Science ®Google Scholar
• Jouhikainen , K. , Lindgren , L. , Jokelainen , T. , Hiltunen , R. , Teeri , T. H. and Oksman-Caldentey , K.-M. 1999 . Enhancement of scopolamine production in Hyoscyamus muticus L. hairy root cultures by genetic engineering . Planta , 208 : 545 – 551 .
   Web of Science ®Google Scholar
• Lichtenthaler , H. K. , Schwender , J. , Disch , A. and Rohmer , M. 1997 . Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate-independent pathway. . FEBS Letters , 400 : 271 – 274 .
   PubMed Web of Science ®Google Scholar
• Ozenberger , B. A. , Brickmann , T. J. and McIntosh , M. A. 1989 . Nucleotide sequence of Escherichia coli isochorismate synthase gene ent C and evolutionary relationship of isochorismate synthase and other chorismate utilizing enzymes. . Journal of Bacteriology , 171 : 775 – 783 .
   PubMed Web of Science ®Google Scholar
• Poulsen , C. , Goddijn , O. J.M. , Hoge , J. H.C. and Verpoorte , R. 1994 . Anthranilate synthase and chorismate mutase activities in transgenic tobacco plants overexpressing tryptophan decarboxylase from . Catharanthus roseus. Transgenic Research , 3 : 43 – 49 .
   Web of Science ®Google Scholar
• Santos , M. C.O. and Winkel , B. S.J. 2000 . “ Modulating flavonoid biosynthesis in transgenic ” . In Arabidopsis. Abstracts of 6th International Congress of Plant Molecular Biology, June 18–24, 2000, Quebec, Canada S10 – 14 .
   Google Scholar
• Schaller , H. , Grausem , B. , Benveniste , P. , Chye , M.-L. , Tan , C.-T. , Song , Y.-H. and Chua , N.-H. 1995 . Expression of the Hevea brasiliensis (H.B.K.) Müll. Arg. 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 in tobacco results in sterol over-production. . Plant Physiology , 109 : 761 – 770 .
   PubMed Web of Science ®Google Scholar
• Siebert , M. , Sommer , S. , Li , S.-M. , Wang , Z.-X. , Severin , K. and Heide , I. 1996 . Genetic engineering of plant secondary metabolism. Accumulation of 4-hydroxy-benzoate glucosides as a result of the expression of the bacterial ubiC gene in tobacco. . Plant Physiology , 112 : 811 – 819 .
   PubMed Web of Science ®Google Scholar
• Sommer , S. , Köhle , A. , Yazaki , K. , Shimomura , K. , Bechthold , A. and Heide , L. 1999 . Genetic engineering of shikonin biosynthesis in hairy root cultures of Litho-spermum erythrorhizon transformed with the bacterial ubiC gene. . Plant Molecular Biology , 39 : 683 – 693 .
   PubMed Web of Science ®Google Scholar
• Tanaka , Y. , Tsuda , S. and Kusumi , T. 1998 . Metabolic engineering to modify flower colour. . Plant Cell Physiology , 39 : 1119 – 1126 .
   Web of Science ®Google Scholar
• Vergauwe , A. , Cammaert , R. , Vandenberghe , D. , Genetello , C. , Inze , D. , Van Montagu , M. and Van Den Eeckhout , E. 1996 . Agrobacterium tumefaciens-mediated transformation of Artemisia annua L. and regeneration of transgenic plants. . Plant Cell Reports , 15 : 929 – 933 .
   PubMed Web of Science ®Google Scholar
• Verpoorte , R. , van der Heiden , R. , ten Hoopen , H. J.G. and Memelink , J. 1999 . Metabolic engineering of plant secondary metabolite pathways for the production of fine chemicals. . Biotechnology Letters , 21 : 467 – 479 .
   Web of Science ®Google Scholar
• Yun , D.-J. , Hashimoto , T. and Yamada , Y. 1992 . Metabolic engineering of medicinal plants: Transgenic Atropa belladonna with an improved alkaloid composition. . Proceedings of the National Academy of Science USA , 89 : 11799 – 11803 .
   PubMed Web of Science ®Google Scholar