4
Views
2
CrossRef citations to date
0
Altmetric
Original Article

Deregulation of the 2,5A Synthetase RNase L Antiviral Pathway by Mycoplasma spp. in Subsets of Chronic Fatigue Syndrome

, , , &
Pages 37-50 | Received 20 Feb 2002, Accepted 02 Sep 2002, Published online: 04 Dec 2011

References

  • Fukuda K, Strauss SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A, and the International Chronic Fatigue Study Group. The Chronic Fatigue Syndrome, a com-prehensive approach to its definition and study. Annals of Internal Medicine 1994; 121: 953–9.
  • Nasralla MY, Haier J, Nicolson NL, Nicolson GL. Examination of mycoplas-mas in blood of 565 chronic illness patients by polymerase chain reaction. Interna-tional Journal of Medical Biology and Environment 2000; 28: 15–23.
  • Nasralla M, Haier J, Nicolson GL. Multiple mycoplasmal infections detected in blood of patients with Chronic Fatigue Syndrome and/or Fibromyalgia. European Journal of Clinical Microbiology and Infectious Diseases 1999; 18: 859–65.
  • Nicolson GL, Nasralla MY, Franco AR, De Meirleir K, Nicolson NL, Ngwenya R, Haier J. Role of mycoplasmal infections in fatigue illnesses: Chronic Fatigue and Fibromylagia Syndromes, Gulf War Illness and Rheumatoid Arthritis. Journal of Chronic Fatigue Syndrome 2000; 6: 23–39.
  • Nicolson GL, Nicolson NL. Diagnosis and treatment of mycoplasmal infections in Persian Gulf War Illness-CFIDS patients. International Journal of Occupational Medicine, Immunology and Toxicology 1996; 5: 67–78.
  • Vojdani A, Franco AB. Multiplex PCR for the detection of Mycoplasma fermentans, M. hominis, and M. penetrans in patients with Chronic Fatigue Syndrome, Fibromyalgia, Rheumatoid Arthritis, and Gulf War Syndrome. Journal of Chronic Fa-tigue Syndrome 1999; 3/4: 187–97.
  • Nicolson GL, Nasralla M, Haier W, Nicolson NL. Diagnosis and treatment of chronic mycoplasmal infections in fibromylagia and chronic fatigue syndromes: rela-tionship to gulf war illness. Biomedical Therapy 1998; 16: 266–71.
  • Suhadolnik RJ, Reichenbach NL, Hitzges P, Sobol RW, Peterson DL, Henry H, et al. Upregulation of the 2-5A synthetase/Rnase L antiviral pathway associated with chronic fatigue syndrome. Clinical Infectious Diseases 1994; 18 Suppl 1: 96–104.
  • Suhadolnik RJ, Peterson DL, Cheney PR, Horvath SE, Reichenbach NL, O'Brien K, et al. Biochemical dysregulation of the 2-5A synthetase/RNase L antiviral defense pathway in chronic fatigue syndrome. Journal of Chronic Fatigue Syndrome 1999; 5: 223–42.
  • De Meirleir K, Bisbal C, Campine I, De Becker P, Salehzada T, Demettre E, Lebleu B. A 37 kDa 2-5A binding protein as a potential biochemical marker for Chronic Fatigue Syndrome. American Journal of Medicine 2000; 108: 99–105.
  • Suhadolnik RJ, Peterson DL, O'Brien K, Cheney PR, Herst CVT, Reichenbach NL, et al. Biochemical evidence for a novel low molecular weight 2-5A-dependent RNase L in chronic fatigue syndrome. Journal of Interferon and Cytokine Research 1997; 17: 377–85.
  • Bisbal C, Martinand C, Silhol M, Lebleu B, Salehzada T. Cloning and charac-terization of a RNase L inhibitor. Journal of Biological Chemistry 1995; 270: 13308–17.
  • Martinand C, Montavon C, Salehzada T, Silhol M, Lebleu B, Bisbal C. RNase L inhibitor is induced during human immunodeficiency virus type 1 infection and down regulates the 2-5A/RNase L pathway in human T cells. Journal of Virology 1999; 73: 290–6.
  • Baum SC. Mycoplasma diseases. In: Mandell GL, Bennett JA, Dolin R, editors. Principles and practice of infectious diseases. New York: Churchill Livingstone, 1995. pp. 1701–12.
  • Baseman J, Tully J. Mycoplasmas: sophisticated, reemerging, and burdened by their notoriety. Emerging Infectious Diseases 1997; 3: 21–32.
  • Simecka JW, Ross SE, Cassell GH, Davis JK. Interactions of mycoplasmas with B cells: antibody production and non-specific effects. Clinical Infectious Dis-eases 1993; 17 Supplement 1: 176–82.
  • Baum SC. Mycoplasma pneumoniae and atypical pneumonia. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and practice of infectious diseases. New York: Chirchill Livingstone 1995, pp. 1713–1718.
  • Englebienne P, Herst CV, Roelens S, D'Haese A, El Bakkouri K, De Smet K, et al. Ribonuclease L: overview of a multifaceted protein. In: Englebienne P, De Meirleir K, editors. Chronic Fatigue Syndrome: a biological approach. Boca Raton: CRC Press, 2002, pp. 17–54.
  • Diaz-Guerra M, Rivas C, Esteban M. Activation of the IFN-inducible RNase L causes apoptosis in animal cells. Virology 1997; 236: 354–63.
  • Castelli J, Wood KA, Youle RJ. The 2-5A system in viral infection and apoptosis. Biomedicine and Pharmacotherapy 1998; 52: 386–90.
  • Fremont M, D'Haese A, Roelens S, De Smet K, Herst CV, Englebienne P. Im-mune cell apoptosis and chronic fatigue syndrome. In: Englebienne P, De Meirleir K, editors. Chronic Fatigue Syndrome: a biological approach. Boca Raton: CRC Press, 2002, pp. 131–74.
  • Martin J, Zeng L, Ahmed K. Cytomegalovirus-related sequence in an atypical cytopathic virus repeatedly isolated from a patient with Chronic Fatigue Syndrome. American Journal of Pathology 1994; 145: 440–51.
  • Martin JW. Detection of RNA sequences in cultures of a stealth virus isolated from the cerebrospinal fluid of a health care worker with Chronic Fatigue Syndrome: case report. Pathobiology 1997; 65: 57–60.
  • Chia JKS, Chia LY. Chronic Chlamydia pneumoniae infection: a treatable cause of chronic fatigue syndrome. Clinical Infectious Diseases 1999; 29: 452–3.
  • Okano M, Thiele GM, Purtilo DT. Severe chronic Epstein-Barr virus infection syndrome and adenovirus type-2 infection. American Journal of Pediatric Hematology Oncology 1990; 12: 168–73.
  • Johnson S, Sidebottom D, Bruckner F, Collins D. Identification of Mycoplasma fermentans in synovial fluid samples from arthritis patients with inflammatory disease. Journal of Clinical Microbiology 2000; 38: 90–3.
  • Schaeverbeke T, Renaudin H, Clerc M, Lequen L, Vernhes JP, De Barbeyrac B, et al. Systemic detection of mycoplasmas by culture and polymerase chain reaction (PCR) procedures in 209 synovial fluid samples. British Journal of Rheumatology 1997; 36: 310–4.
  • Hoffman RW, O'Sullivan FX, Schafermeyer KR, Moore TL, Roussell D, Wat-son-McKown R, et al. Mycoplasma infection and rheumatoid arthritis. Arthritis and Rheumatism 1997; 40: 1219–28.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.