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Original Articles

Liver Toxicity of Initial Antiretroviral Drug Regimens Including Two Nucleoside Analogs Plus One Non-Nucleoside Analog or One Ritonavir-Boosted Protease Inhibitor in HIV/HCV-Coinfected Patients

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Pages 61-69 | Published online: 06 Jan 2015

REFERENCES

  • Thein HH, Yi Q, Dore GJ, Krahn MD. Natural history of hepatitis C virus infection in HIV-infected individuals and the impact of HIV in the era of highly active antiretroviral therapy: a meta-analysis. AIDS. 2008;22:1979–1991.
  • Macias J, Berenguer J, Japón MA, et al. Fast fibrosis progression between repeated liver biopsies in patients coinfected with human immunodeficiency virus/hepatitis C virus. Hepatology. 2009;50:1056–1063.
  • Pineda JA, Garcia-Garcia JA, Aguilar-Guisado M, et al. Clinical progression of hepatitis C virus-related chronic liver disease in human immunodeficiency virus-infected patients undergoing highly active antiretroviral therapy. Hepatology. 2007;46:622–630.
  • Dieleman JP, Jambroes M, Gyssens IC, et al. Deter-minants of recurrent toxicity-driven switches of highly active antiretroviral therapy. The ATHENA cohort. AIDS. 2002;16:737–745.
  • Jain MK. Drug-induced liver injury associated with HIV medications. Clin Liver Dis. 2007;11:615–639.
  • Soriano V, Koeppe S, Mingrone H, et al. Prospective comparison of nevirapine and atazanavir/ritonavir both combined with tenofovir DF/emtricitabine in treatment-naïve HIV-1 infected patients: ARTEN study week 48 results. Presented at: 5th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Preven-tion (IAS) 2009; July 19–22, 2009; Cape Town, South Africa. Abstract LBPEB07.
  • van Leth F, Phanuphak P, Ruxrungthan K, et al. Compari-son of first-line antiretroviral therapy with regimens includ-ing nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomized open-label trial, the 2NN study. Lancet. 2004;363:1253–1263.
  • da Silva B, King M, Cernohous P, et al. Lopinavir/ritona-vir (LPV/r) safety, tolerability and efficacy in HIV patients co-infected with hepatitis C and/or hepatitis B: review of clinical trials. In: Program and abstracts of the The XV International AIDS Conference; 2004; Bangkok. Abstract MoPeB3285.
  • Norris D, Patel L, Rizzardini G, et al. Efficacy and safety of fosamprenavir/ritonavir (FPV/r) bid or lopinavir/ritona-vir (LPV/r) bid in antiretroviral treatment-naïve subjects co-infected with hepatitis B (HBV) or C (HCV) and HIV (the KLEAN study). In: Program and abstracts of the 4th International AIDS Society (IAS) Conference on HIV Pathogenenesis, Treatment and Prevention; 2007; Sydney. Abstract MOPEB059.
  • Absalon J, Thal G, Thiry A, et al. Atazanavir is safe and effi-cacious in HBV and HCV co-infected patients: results of A1424138 (CASTLE). In: Program and abstracts of the 9th International Congress on Drug Therapy in HIV Infection; 2008; Glasgow. Abstract P136.
  • Ortiz R, Fourie J, Andrade-Villanueva J, et al. Tolerability of once-daily darunavir/r versus lopinavir/r in treatment naive patients coinfected with hepatitis B and/or C in the ARTEMIS trial. In: Program and abstracts of the HEP DART: Frontiers in Drug Development for Viral Hepatitis; 2007; Hawaü. Abstract 97.
  • Pineda JA, Santos J, Rivero A, et al. Liver toxicity of anti-retroviral combinations including atazanavir/ritonavir in patients co-infected with HIV and hepatitis viruses: impact of pre-existing liver fibrosis. J Antimicrob Chemother. 2008;61:925–932.
  • Palacios R, Vergara S, Rivero A, et al. Low incidence of severe liver events in HIV patients with and without hepati-tis C or B coinfection receiving lopinavir/ritonavir. HIV Clin Trials. 2006;7:319–323.
  • Sulkowski MS, Thomas DL, Mehta SH, Chaisson RE, Moore RD. Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: role of hepatitis C and B infections. Hepatology. 2002;35:182–189.
  • Martin-Carbonero L, Nunez M, González-Lahoz, et al. Incidence of liver injury after beginning antiretrovi-ral therapy with efavirenz or nevirapine. HIV Clin Trials. 2003;4:115–278.
  • Martinez E, Blanco J, Arnaiz J, et al. Hepatotoxicity in HIV-infected patients receiving nevirapine containing anti-retroviral therapy. AIDS. 2001;15:1261–1268.
  • Scheuer PJ. Classification of chronic viral hepatitis: a need for reassessment. J Hepatol. 1991;13:372–374.
  • Sustiva [efavirenz] capsules and tablet. Safety labeling changes approved by FDA Center for Drug Evaluation and Research (CDER). March 2010. http://www.fda.gov/Safety/MedWatch/SafetyInformation/ucm208409.htm. Accessed at May 18,2010.
  • FDA Public Health Advisory for nevirapine [Viramune]. http://www.fda.gov/Drugs/DrugSafety/PublicHealthAd-visories/ucm051674.htm. Accessed at May 18, 2010.
  • Chalasani N, Bjärnsson E. Risk factors for idiosyn-cratic drug-induced liver injury. Gastroenterology. 2010;138:2246–2259.

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