Beta-cell Activity and Destruction in Type 1 Diabetes

References

• Agner, T. Damm, P. Binder, C. Remission in IDDM: Prospective study of basal C-peptide and insulin dose in 268 consecutive patients Diabetes Care 1987 10 164–169.
   PubMed Web of Science ®Google Scholar
• Atkinson, M.A. Maclaren, N.K. Luchetta, R. Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy Diabetes 1990 39 933–937.
   PubMed Web of Science ®Google Scholar
• Bach, J.F. Insulin-dependent diabetes mellitus as an autoimmune disease Endocr Rev 1994 15 516–542.
   PubMed Web of Science ®Google Scholar
• Baekkeskov, S. Aanstoot, J. Christgau, S. Reetz, A. Solimena, M. Cascalho, M. Folli, F. Richter-Olesen, H. DeCamilli, P. Identification of the 64K antigen in insulin-dependent diabetes as the GABA-syntesizing enzyme glutamic acid decarboxylase Nature 1990 347 151–156.
   PubMed Web of Science ®Google Scholar
• Björk, E. Berne, C. Karlsson, F.A. Induction of beta-cell rest in type 1 diabetes. Studies on the effects of octreotide and diazoxide Diabetes Care 1998 21 427–430.
   PubMed Web of Science ®Google Scholar
• Björk, E. Berne, C. Kämpe, O. Wibell, L. Oskarsson, P. Karlsson, F.A. Diazoxide treatment at onset preserves residual insulin secretion in adults with autoimmune diabetes Diabetes 1996 45 1427–1430.
   PubMed Web of Science ®Google Scholar
• Björk, E. Kämpe, O. Andersson, A. Karlsson, F.A. Expression of the 64 kDa/ GAD rat islet cell autoantigen is influenced by the rate of insulin secretion Diabetologia 1992 32 490–493.
   Web of Science ®Google Scholar
• Björk, E Kämpe, O Karlsson, F.A. Pipeleers, D.G. Anderssson, A. Hellerström, C. Eizirik, D.L. Glucose regulation of the autoantigen GAD65 in human pancreatic islets J Clin Endocrinol Metab 1992 75 1574–1576.
   PubMedGoogle Scholar
• Cai, Z Brunmark, A.B. Luxembourg, A.T. Garcia, K.C. Degano, M. Teyton, L. Wilson, I. Peterson, P.A. Sprent, J. Jackson, M.R. Probing the activation requirements for naive CD8+ T cells with Drosophila cell transfectants as antigen presenting cells Immunol Rev 1998 165 249–265.
   PubMed Web of Science ®Google Scholar
• Campbell, I.L. Harrison, L.C. Molecular pathology of type 1 diabetes Mol Biol Med 1990 7 299–309.
   PubMedGoogle Scholar
• Cole, W.C. McPherson, C.D. Sontag, D. ATP-regulated K+ channels protect the myocardium against ischemia/reperfusion damage Circ Res 1991 69 571–581.
   PubMed Web of Science ®Google Scholar
• Conget, I. Fernandez-Alvarez, J. Ferrer, J. Sarri, Y. Novials, A. Somoza, N. Pujol-Borrel, R. Casamitjana, R. Gomis, R. Human pancreatic islet function at the onset of type 1 (insulin-dependent diabetes mellitus Diabetologia 1993 36 358–360.
   PubMed Web of Science ®Google Scholar
• Czarnocka, B. Ruf, J. Ferrand, M. Carayon, P. Lissitzky, S. Purification of the human thyroid peroxidase and its identification as the microsomal antigen involved in autoimmune thyroid disease FEBS Lett 1985 190 147–151.
   PubMed Web of Science ®Google Scholar
• Effect of intensive therapy on residual beta-cell function in patients with type 1 diabetes in the diabetes control and complications trial. A randomized, controlled trial. The Diabetes Control and Complications Trial Research Group Ann Intern Med 1998 128 517–23.
   PubMed Web of Science ®Google Scholar
• Eisenbarth, G.S. Type I diabetes mellitus: A chronic autoimmune disease N Engl J Med 1986 314 1360–1368.
   PubMed Web of Science ®Google Scholar
• Eizirik, DL Strandell, E. Sandler, S. Culture of mouse pancreatic islets in different glucose concentrations modifies the B-cell sensitivity to streptozotocin Diabetologia 1988 31 168–174.
   PubMed Web of Science ®Google Scholar
• Erecinska, M. Bryla, J. Michalik, M. Meglasson, M.D. Nelson, D. Energy metabolism in islets of Langerhans Biochim Biophys Acta 1992 1101 273–295.
   PubMed Web of Science ®Google Scholar
• Fukuda, M. Tanaka, A. Tahara, Y. Ikegami, H. Yamamoto, Y. Kumahara, Y. Shima, K. Correlation between minimal secretory capacity of pancreatic beta-cells and stability of diabetic control Diabetes 1988 37 81–88.
   PubMed Web of Science ®Google Scholar
• Garlid, K.D. Paucek, P. Yarov-Yarovoy, V. Murray, H.N. Darbenzio, R.B. D'Alonzo, A.J. Lodge, N.J. Smith, M.A. Grover, G.J. Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels. Possible mechanism of cardioprotection Circ Res 1997 81 1072–1082.
   PubMed Web of Science ®Google Scholar
• Gotfredsen, C.F. Buschard, K. Frandsen, E.K. Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals Diabetologia 1985 28 933–935.
   PubMed Web of Science ®Google Scholar
• Grimmsmann, T. Rustenbeck, I. Direct effects of diazoxide on mitochondria in pancreatic B-cells and on isolated liver mitochondria Br J Pharmacol 1998 123 781–788.
   PubMed Web of Science ®Google Scholar
• Grimmsmann, T. Rustenbeck, I. Direct effects of diazoxide on mitochondria in pancreatic B-cells and on isolated liver mitochondria Br J Pharmacol 1998 123 781–788.
   PubMed Web of Science ®Google Scholar
• Grover, G.J. Newburger, J. Sleph, P.G. Dzwonczyk, S. Taylor, S.C. Ahmed, S.Z. Atwal, K.S. Cardioprotective effects of the potassium channel opener cromakalim: Stereoselectivity and effects on myocardial adenine nucleotides J. Pharmacol. Exp. Ther. 1991 257 156–162.
   PubMed Web of Science ®Google Scholar
• Hagopian, W.A. Karlsen, A.E. Petersen, J.S. Teague, J. Gerrassi, A. Jiang, J. Fujimoto, W. Lernmark, Å. Regulation of glutamic acid decarboxylase diabetes autoantigen expression in highly purified isolated islets from Macaca nemestrina Endocrinology 1993 132 2674–2681.
   PubMed Web of Science ®Google Scholar
• Hanninen, A. Jalkanen, S. Salmi, M. Toikkanen, S. Nikolakaros, G. Simell, O. Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus J Clin Invest 1992 90 1901–1910.
   PubMed Web of Science ®Google Scholar
• Heaton, D.A. Millward, B.A. Gray, P. Tun, Y. Hales, C.N. Pyke, D.A. Leslie, R.D. Evidence of beta-cell dysfunction which does not lead on to diabetes: A study of identical twins of insulin dependent diabetics Br Med J 1987 294 145–146.
   PubMedGoogle Scholar
• Henquin, J.C. Meissner, H.P. Opposite effects of tolbutamide and diazoxide on 86Rb+ fluxes and membrane potential in pancreatic B cells Biochem Pharmacol 1982 31 1407–1415.
   PubMed Web of Science ®Google Scholar
• Janeway, C.A. Bottomly, K. Signals and signs for lymphocyte responses Cell 1994 76 275–285.
   PubMed Web of Science ®Google Scholar
• Karlsson, F.A. Björk, E. Beta-cell rest: A strategy for the prevention of autoimmune diabetes Autoimmunity 1997 26 117–122.
   PubMed Web of Science ®Google Scholar
• Karlsson, F.A. Burman, P. Lööf, L. Mårdh, S. The major parietal cell antigen in autoimmune gastritis with pernicious anemia is the acid-producing H+, K+-ATPase of the stomach J Clin Invest 1988 81 475–9.
   PubMed Web of Science ®Google Scholar
• Kullin, M. Li, Z.C. Hansen, J.B. Björk, E. Sandler, S. Karlsson, F.A. KATP channel openers protect rat islets against the toxic effect of streptozotocin Diabetes 2000 in press.
   Google Scholar
• Kämpe, O. Andersson, A. Björk, E. Hallberg, A. Karlsson, F.A. High-glucose stimulation of 64,000-Mr islet cell autoantigen expression Diabetes 1989 38 1326–1328.
   PubMed Web of Science ®Google Scholar
• Lampeter, E.F. Homberg, M. Quabeck, K. Shaefer, U.W. Wernet, P. Bertarms, J. Grosse-Wilde, H. Gries, F.A. Kolb, H. Transfer of insulin-dependent diabetes between HLA-identical siblings by bone marrow transplantation Lancet 1993 341 1243–1244.
   PubMed Web of Science ®Google Scholar
• Li, Z. Zhao, L. Sandler, S. Karlsson, F.A. Expression of pancreatic islet MHC class I, insulin and ICA 512 tyrosine phosphatase in low-dose streptozotocin-induced diabetes in mice J Histochem Cytochem 2000 48 in press.
   Google Scholar
• Like, A.A. Rossini, A.A. Streptozotocin-induced pancreatic insulitis: New model of diabetes mellitus Science 1976 193 415–417.
   PubMed Web of Science ®Google Scholar
• Ludvigsson, J. Heding, L.G. Beta-cell function in children with diabetes Diabetes 1978 27 230–234.
   PubMed Web of Science ®Google Scholar
• Matis, L.A. Glimcher, L.H. Paul, W.E. Schwartz, R.H. Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules Proc Natl Acad Sci U S A 1983 80 19 6019–6023.
   PubMed Web of Science ®Google Scholar
• McCulloch, D.K. Barmeier, H. Neifing, J.L. Palmer, J.P. Metabolic state of the pancreas affects end-point titre in the islet cell antibody assay Diabetologia 1991 34 622–625.
   PubMed Web of Science ®Google Scholar
• McCulloch, D.K. Klaff, L.J. Kahn, S.E. Schoenfeld, S.L. Groenbaum, C.J. Mauseth, R.S. Benson, E.A. Nepom, G.T. Shewey, L. Palmer, J.P. Nonprogression of subclinical beta-cell dysfunction among first-degree relatives of IDDM patients. 5-year follow-up of the Seattle Family Study Diabetes 1990 39 549–556.
   PubMed Web of Science ®Google Scholar
• McCulloch, D.K. Koerker, D.J. Kahn, S.E. Bonner-Weir, S. Palmer, J.P. Correlations of in vivo beta-cell function tests and beta-cell mass and pancreatic insulin content in streptozotocin-administered baboons Diabetes 1991 40 673–679.
   PubMed Web of Science ®Google Scholar
• Nakanishi, K. Kobayashi, T. Inoko, H. Tsuji, K. Murase, T. Kosaka, K. Residual beta-cell function and HLA-A24 in IDDM. Markers of glycemic control and subsequent development of diabetic retinopathy Diabetes 1995 44 1334–1339.
   PubMed Web of Science ®Google Scholar
• Palmer, J.P. McCulloch, D.K. Prediction and prevention of IDDM — 1991 Diabetes 1991 40 943–947.
   PubMed Web of Science ®Google Scholar
• Palmer, J.P. Helqvist, SpinasG. A. Molvig, J. Mandrup-Poulsen, T. Andersen, H.U. Nerup, J. Interaction of beta-cell activity and IL-1 concentration and exposure time in isolated rat islets of Langerhans Diabetes 1989 38 1211–1216.
   PubMed Web of Science ®Google Scholar
• Rouslin, W. Broge, C.W. Mechanisms of ATP conservation during ischemia in slow and fast heart rate hearts Am J Physiol 1993 264 C209–C216.
   Google Scholar
• Solimena, M. Dirkx, R. Jr. Hermel, J.M. Pleasic-Williams, S. Shapiro, J.A. Caron, L. Rabin, D.U. ICA 512, an autoantigen of type 1 diabetes, is an intrinsic membrane protein of neurosecretory granules EMBO J 1996 15 2102–2114.
   PubMed Web of Science ®Google Scholar
• Strandell, E. Eizirik, D.L. Sandler, S. Reversal of beta-cell suppression in pancreatic islets isolated from nonobese diabetic mice during the phase preceding insulin-dependent diabetes mellitus J Clin Invest 1990 85 1944–1950.
   PubMed Web of Science ®Google Scholar
• Sutherland, D.E. Goetz, F.C. Sibley, R.K. Recurrence of disease in pancreas transplants Diabetes 1989 38 85–87.
   PubMed Web of Science ®Google Scholar
• The Diabetes Control and Complication Trial Research Group The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus N Engl J Med 1993 329 977–986.
   PubMed Web of Science ®Google Scholar
• Thivolet, C.H. Goillot, E. Bedossa, P. Durand, A. Bonnard, M. Orgiazzi, J. Insulin prevents adoptive cell transfer of diabetes in autoimmune non-obese diabetic mouse Diabetologia 1991 34 314–319.
   PubMed Web of Science ®Google Scholar
• Verge, C.F. Stenger, D. Bonifacio, E. Colman, P.G. Pilcher, C. Bingley, P.J. Eisenbarth, G.S. Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop Diabetes 1998 47 1857–1866.
   PubMed Web of Science ®Google Scholar
• Vialettes, B. Maraninchi, D. San Marco, M.P. Birg, F. Stoppa, A.M. Mattei-Zevaco, C. Thivolet, C. Hermitte, L. Vague, P. Mercier, P. Autoimmune polyendocrine failure — type 1 (insulin-dependent) diabetes mellitus and hypothyroidism — after allogeneic bone marrow transplantation in a patient with lymphoblastic leukemia Diabetologia 1993 36 541–546.
   PubMed Web of Science ®Google Scholar
• Winqvist, O. Karlsson, F.A. Kämpe, O. 21-hydroxylase, a major autoantigen in idiopathic Addison's disease Lancet 1992 339 1559–1562.
   PubMed Web of Science ®Google Scholar
• Yamamoto, H. Uchigata, Y. Okamoto, H. Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthase in pancreatic islets Nature 1981 294 5838 284–286.
   PubMed Web of Science ®Google Scholar