307
Views
19
CrossRef citations to date
0
Altmetric
Patenting Perspective

Small molecules for stem cells

, PhD
Pages 275-281 | Published online: 27 Mar 2009

Bibliography

  • French AJ, Adams CA, Anderson LS, et al. Development of human cloned blastocysts following somatic cell nuclear transfer with adult fibroblasts. Stem Cells 2008;26(2):485-93
  • Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-72
  • Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells. Science 2007;318:1917-20
  • Advanced Cell Tech Inc. De-differentiation and re-differentiation of somatic cells and production of cells for cell therapies. US2008076176; 2008
  • Chen S, Zhang Q, Wu X, et al. Dedifferentiation of lineage-committed cells by a small molecule. J Am Chem Soc 2004;126(2):410-1
  • Shi Y, Do JT, Desponts C, et al. A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell 2008;2(6):525-8
  • Huangfu D, Maehr R, Guo W, et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol 2008;26(7):795-7
  • Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004;20:781-810
  • Meijer L, Skaltsounis AL, Magiatis P, et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol 2003;10:1255-66
  • Sato N, Meijer L, Skaltsounis L, et al. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004;10:55-63
  • Athersys, Inc. Use of a gsk-3 inhibitor to maintain potency of cultured cells. WO2007016485; 2007
  • Ding S, Wu TY, Brinker A, et al. Synthetic small molecules that control stem cell fate. Proc Natl Acad Sci USA 2003;100(13):7632-7
  • Chen S, Do JT, Zhang Q, et al. Self-renewal of embryonic stem cells by a small molecule. Proc Natl Acad Sci USA 2006;103(46):17266-71
  • Irm Llc., Scripps Research Inst. Compounds that maintain pluripotency of embryonic stem cells. KR20080024194; 2008
  • Miyabayashi T, Yamamoto M, Sato A, et al. Indole derivatives sustain embryonic stem cell self-renewal in long-term culture. Biosci Biotechnol Biochem 2008;72(5):1242-8
  • Graichen R, Xu X, Braam SR, et al. Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK. Differentiation 2008;76(4):357-70
  • Es Cell Int Pte Ltd. Direct differentiation of cardiomyocytes from human embryonic stem cells. WO2007070964; 2007
  • Wu X, Ding S, Ding Q, et al. Small molecules that induce cardiomyogenesis in embryonic stem cells. J Am Chem Soc 2004;126(6):1590-1
  • Paling NR, Wheadon H, Bone HK, Welham MJ. Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling. J Biol Chem 2004;279:48063-70
  • Armstrong L, Hughes O, Yung S, et al. The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis. Hum Mol Genet 2006;15:1894-1913
  • Cythera Inc. Modulation of the phosphatidylinositol-3-kinase pathway in the differentiation of human embryonic stem cells. WO2008048647; 2008
  • Carpenter MK, Thies RS. Use of cyclic AMP and ascorbic acid to produce dopaminergic neurons from embryonic stem cells. US2005095707; 2005;
  • Iacovitti L, Donaldson AE, Marshall CE, et al. A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: studies in vitro and in vivo. Brain Res 2007;1127(1):19-25
  • Cheng H. Method for inducing neural differentiation. US2008175829; 2008
  • Univ Florida. Neurogenesis from hepatic stem cells. WO2004020601; 2004
  • Osiris Therapeutics Inc. Adipogenic differentiation of human mesenchymal stem cells. EP1659172; 2006

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.